Jon S. Thorson
Jon S. Thorson
Professor of Pharmaceutical Sciences, University of Kentucky College of Pharmacy
Verified email at uky.edu - Homepage
Title
Cited by
Cited by
Year
Antitumor antibiotics: Bleomycin, enediynes, and mitomycin
U Galm, MH Hager, SG Van Lanen, J Ju, JS Thorson, B Shen
Chemical Reviews 105 (2), 739-758, 2005
5092005
Nicotinic receptor binding site probed with unnatural amino acid incorporation in intact cells
MW Nowak, PC Kearney, JR Sampson, ME Saks, CG Labarca, ...
Science 268 (5209), 439-439, 1995
3941995
A genomics-guided approach for discovering and expressing cryptic metabolic pathways
E Zazopoulos, K Huang, A Staffa, W Liu, BO Bachmann, K Nonaka, ...
Nature Biotechnology 21 (2), 187-190, 2003
3632003
Pathways and mechanisms in the biogenesis of novel deoxysugars by bacteria
H Liu, JS Thorson
Annual Reviews in Microbiology 48 (1), 223-256, 1994
3211994
The calicheamicin gene cluster and its iterative type I enediyne PKS
J Ahlert, E Shepard, N Lomovskaya, E Zazopoulos, A Staffa, ...
Science 297 (5584), 1173-1176, 2002
3202002
Exploiting the reversibility of natural product glycosyltransferase-catalyzed reactions
C Zhang, BR Griffith, Q Fu, C Albermann, X Fu, IK Lee, L Li, JS Thorson
Science 313 (5791), 1291-1294, 2006
2822006
Structure, activity, synthesis and biosynthesis of aryl-C-glycosides
T Bililign, BR Griffith, JS Thorson
Natural Product Reports 22 (6), 742-760, 2005
2742005
Enhancing the anticancer properties of cardiac glycosides by neoglycorandomization
JM Langenhan, NR Peters, IA Guzei, FM Hoffmann, JS Thorson
Proceedings of the National Academy of Sciences 102 (35), 12305-12310, 2005
2522005
Expanding the promiscuity of a natural-product glycosyltransferase by directed evolution
GJ Williams, C Zhang, JS Thorson
Nature Chemical Biology 3 (10), 657-662, 2007
2482007
Antibiotic optimization via in vitro glycorandomization
X Fu, C Albermann, J Jiang, J Liao, C Zhang, JS Thorson
Nature Biotechnology 21 (12), 1467-1469, 2003
2402003
Enzymatic methods for glyco (diversification/randomization) of drugs and small molecules
RW Gantt, P Peltier-Pain, JS Thorson
Natural Product Reports 28 (11), 1811-1853, 2011
2022011
Understanding and exploiting nature's chemical arsenal: The past, present and future of calicheamicin research
JS Thorson, EL Sievers, J Ahlert, E Shepard, RE Whitwam, KC Onwueme, ...
Current Pharmaceutical Design 6 (18), 1841-1879, 2000
1952000
Nature's carbohydrate chemists: The enzymatic glycosylation of bioactive bacterial metabolites
JS Thorson, TJ Hosted Jr, J Jiang, JB Biggins, J Ahlert
Current Organic Chemistry 5 (2), 139-167, 2001
1922001
A comprehensive review of glycosylated bacterial natural products
SI Elshahawi, KA Shaaban, MK Kharel, JS Thorson
Chemical Society Reviews 44 (21), 7591-7697, 2015
1832015
‘Sweetening’natural products via glycorandomization
BR Griffith, JM Langenhan, JS Thorson
Current Opinion in Biotechnology 16 (6), 622-630, 2005
1732005
Enzymatic tools for engineering natural product glycosylation
S Blanchard, JS Thorson
Current Opinion in Chemical Biology 10 (3), 263-271, 2006
1662006
Incorporation of glucose analogs by GtfE and GtfD from the vancomycin biosynthetic pathway to generate variant glycopeptides
HC Losey, J Jiang, JB Biggins, M Oberthür, XY Ye, SD Dong, D Kahne, ...
Chemistry & Biology 9 (12), 1305-1314, 2002
1652002
Neoglycorandomization and chemoenzymatic glycorandomization: Two complementary tools for natural product diversification
JM Langenhan, BR Griffith, JS Thorson
Journal of Natural Products 68 (11), 1696-1711, 2005
1522005
Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization
WA Barton, J Lesniak, JB Biggins, PD Jeffrey, J Jiang, KR Rajashankar, ...
Nature structural biology 8 (6), 545-551, 2001
1442001
Probing the aglycon promiscuity of an engineered glycosyltransferase
RW Gantt, RD Goff, GJ Williams, JS Thorson
Angewandte Chemie International Edition 47 (46), 8889-8892, 2008
1332008
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