Alaa A.-M. Abdel-Aziz
Alaa A.-M. Abdel-Aziz
Mansoura University
Verified email at ksu.edu.sa
TitleCited byYear
Design, synthesis and biological evaluation of novel quinazoline derivatives as potential antitumor agents: molecular docking study
AS El-Azab, MA Al-Omar, AM Alaa, NI Abdel-Aziz, AA Magda, AM Aleisa, ...
European journal of medicinal chemistry 45 (9), 4188-4198, 2010
1942010
Synthesis, dihydrofolate reductase inhibition, antitumor testing, and molecular modeling study of some new 4 (3H)-quinazolinone analogs
ST Al-Rashood, IA Aboldahab, MN Nagi, LA Abouzeid, AAM Abdel-Aziz, ...
Bioorganic & medicinal chemistry 14 (24), 8608-8621, 2006
1752006
Substituted quinazolines, part 3. Synthesis, in vitro antitumor activity and molecular modeling study of certain 2-thieno-4 (3H)-quinazolinone analogs
AM Al-Obaid, SG Abdel-Hamide, HA El-Kashef, AM Alaa, AS El-Azab, ...
European journal of medicinal chemistry 44 (6), 2379-2391, 2009
1652009
Novel and versatile methodology for synthesis of cyclic imides and evaluation of their cytotoxic, DNA binding, apoptotic inducing activities and molecular modeling study
AM Alaa
European journal of medicinal chemistry 42 (5), 614-626, 2007
1482007
Non-classical antifolates. Part 2: synthesis, biological evaluation, and molecular modeling study of some new 2, 6-substituted-quinazolin-4-ones
FAM Al-Omary, LA Abou-Zeid, MN Nagi, ESE Habib, AM Alaa, AS El-Azab, ...
Bioorganic & medicinal chemistry 18 (8), 2849-2863, 2010
1352010
Design, synthesis, and biological evaluation of substituted hydrazone and pyrazole derivatives as selective COX-2 inhibitors: Molecular docking study
AA Magda, NI Abdel-Aziz, AM Alaa, AS El-Azab, YA Asiri, KEH ElTahir
Bioorganic & medicinal chemistry 19 (11), 3416-3424, 2011
1232011
Synthesis, antimicrobial activity and conformational analysis of novel substituted pyridines: BF3-promoted reaction of hydrazine with 2-alkoxy pyridines
FE Goda, AM Alaa, OA Attef
Bioorganic & medicinal chemistry 12 (8), 1845-1852, 2004
1162004
Synthesis, biological evaluation and molecular modeling study of pyrazole and pyrazoline derivatives as selective COX-2 inhibitors and anti-inflammatory agents. Part 2
AA Magda, NI Abdel-Aziz, AM Alaa, AS El-Azab, KEH ElTahir
Bioorganic & medicinal chemistry 20 (10), 3306-3316, 2012
952012
Synthesis, anti-inflammatory activity and COX-1/COX-2 inhibition of novel substituted cyclic imides. Part 1: Molecular docking study
AM Alaa, KEH ElTahir, YA Asiri
European journal of medicinal chemistry 46 (5), 1648-1655, 2011
822011
Oral colon targeted delivery systems for treatment of inflammatory bowel diseases: synthesis, in vitro and in vivo assessment
AH El-Kamel, AM Alaa, AJ Fatani, HI El-Subbagh
International journal of pharmaceutics 358 (1-2), 248-255, 2008
682008
Lewis acid-promoted transformation of 2-alkoxypyridines into 2-aminopyridines and their antibacterial activity. Part 2: Remarkably facile C–N bond formation
AM Alaa, HI El-Subbagh, T Kunieda
Bioorganic & medicinal chemistry 13 (16), 4929-4935, 2005
622005
Synthesis, antimicrobial activity and molecular modeling of cobalt and nickel complexes containing the bulky ligand: bis [N-(2, 6-diisopropylphenyl) imino] acenaphthene
U El-Ayaan, AM Alaa
European journal of medicinal chemistry 40 (12), 1214-1221, 2005
612005
Structure-based design of phthalimide derivatives as potential cyclooxygenase-2 (COX-2) inhibitors: anti-inflammatory and analgesic activities
AM Alanazi, AS El-Azab, IA Al-Suwaidan, KEH ElTahir, YA Asiri, ...
European journal of medicinal chemistry 92, 115-123, 2015
512015
Design, synthesis and antibacterial activity of fluoroquinolones containing bulky arenesulfonyl fragment: 2D-QSAR and docking study
AM Alaa, YA Asiri, MHM Al-Agamy
European journal of medicinal chemistry 46 (11), 5487-5497, 2011
462011
Synthesis and antitumor evaluation of novel cyclic arylsulfonylureas: ADME-T and pharmacophore prediction
IM El-Deeb, SM Bayoumi, MA El-Sherbeny, AM Alaa
European journal of medicinal chemistry 45 (6), 2516-2530, 2010
412010
Synthesis and biological evaluation of novel 6-nitro-5-substituted aminoquinolines as local anesthetic and anti-arrhythmic agents: molecular modeling study
FE Goda, AM Alaa, HA Ghoneim
Bioorganic & medicinal chemistry 13 (9), 3175-3183, 2005
412005
Design, synthesis and biological evaluation of some novel substituted quinazolines as antitumor agents
AM Alanazi, AM Alaa, IA Al-Suwaidan, SG Abdel-Hamide, TZ Shawer, ...
European journal of medicinal chemistry 79, 446-454, 2014
392014
Molecular design, synthesis and biological evaluation of cyclic imides bearing benzenesulfonamide fragment as potential COX-2 inhibitors. Part 2
IA Al-Suwaidan, AM Alanazi, AS El-Azab, AM Al-Obaid, KEH ElTahir, ...
Bioorganic & medicinal chemistry letters 23 (9), 2601-2605, 2013
382013
Synthesis and biological evaluation of some novel cyclic-imides as hypoglycaemic, anti-hyperlipidemic agents
AM Alaa, AS El-Azab, SM Attia, AM Al-Obaid, MA Al-Omar, HI El-Subbagh
European journal of medicinal chemistry 46 (9), 4324-4329, 2011
382011
Design, synthesis and biological evaluation of 2-mercapto-3-phenethylquinazoline bearing anilide fragments as potential antitumor agents: molecular docking study
IA Al-Suwaidan, AM Alanazi, AM Alaa, MA Mohamed, AS El-Azab
Bioorganic & medicinal chemistry letters 23 (13), 3935-3941, 2013
352013
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