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James Varani
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Mechanisms of photoaging and chronological skin aging
GJ Fisher, S Kang, J Varani, Z Bata-Csorgo, Y Wan, S Datta, JJ Voorhees
Archives of dermatology 138 (11), 1462-1470, 2002
21982002
Pathophysiology of premature skin aging induced by ultraviolet light
GJ Fisher, ZQ Wang, SC Datta, J Varani, S Kang, JJ Voorhees
New England Journal of Medicine 337 (20), 1419-1429, 1997
18391997
Molecular basis of sun-induced premature skin ageing and retinoid antagonism
GJ Fisher, SC Datta, HS Talwar, ZQ Wang, J Varani, S Kang, JJ Voorhees
Nature 379 (6563), 335-339, 1996
18171996
Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulation
J Varani, MK Dame, L Rittie, SEG Fligiel, S Kang, GJ Fisher, JJ Voorhees
The American journal of pathology 168 (6), 1861-1868, 2006
10432006
Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin1
J Varani, RL Warner, M Gharaee-Kermani, SH Phan, S Kang, JH Chung, ...
Journal of investigative dermatology 114 (3), 480-486, 2000
8132000
Looking older: fibroblast collapse and therapeutic implications
GJ Fisher, J Varani, JJ Voorhees
Archives of dermatology 144 (5), 666-672, 2008
6672008
In vivo stimulation of de novo collagen production caused by cross-linked hyaluronic acid dermal filler injections in photodamaged human skin
F Wang, LA Garza, S Kang, J Varani, JS Orringer, GJ Fisher, JJ Voorhees
Archives of dermatology 143 (2), 155-163, 2007
6282007
Collagen fragmentation promotes oxidative stress and elevates matrix metalloproteinase-1 in fibroblasts in aged human skin
GJ Fisher, T Quan, T Purohit, Y Shao, MK Cho, T He, J Varani, S Kang, ...
The American journal of pathology 174 (1), 101-114, 2009
5202009
Role of endothelial-leukocyte adhesion molecule 1 (ELAM-1) in neutrophil-mediated lung injury in rats.
MS Mulligan, J Varani, MK Dame, CL Lane, CW Smith, DC Anderson, ...
The Journal of clinical investigation 88 (4), 1396-1406, 1991
4901991
Matrix Metalloproteinase‐1 is the Major Collagenolytic Enzyme Responsible for Collagen Damage in UV‐irradiated Human Skin
M Brennan, H Bhatti, KC Nerusu, N Bhagavathula, S Kang, GJ Fisher, ...
Photochemistry and photobiology 78 (1), 43-48, 2003
4312003
Effects of 5-fluorouracil and mitomycin C on cultured rabbit subconjunctival fibroblasts
T Yamamoto, J Varani, HK Soong, PR Lighter
Ophthalmology 97 (9), 1204-1210, 1990
4201990
Inhibition of type I procollagen synthesis by damaged collagen in photoaged skin and by collagenase-degraded collagen in vitro
J Varani, D Spearman, P Perone, SEG Fligiel, SC Datta, ZQ Wang, ...
The American journal of pathology 158 (3), 931-942, 2001
4142001
Improvement of naturally aged skin with vitamin A (retinol)
R Kafi, HSR Kwak, WE Schumacher, S Cho, VN Hanft, TA Hamilton, ...
Archives of dermatology 143 (5), 606-612, 2007
3512007
Pomegranate as a cosmeceutical source: Pomegranate fractions promote proliferation and procollagen synthesis and inhibit matrix metalloproteinase-1 production in human skin cells
MN Aslam, EP Lansky, J Varani
Journal of ethnopharmacology 103 (3), 311-318, 2006
3302006
Pulmonary endothelial cell killing by human neutrophils. Possible involvement of hydroxyl radical.
J Varani, SE Fligiel, GO Till, RG Kunkel, US Ryan, PA Ward
Laboratory investigation; a journal of technical methods and pathology 53 (6 …, 1985
3281985
Collagen degradation in aged/photodamaged skin in vivo and after exposure to matrix metalloproteinase-1 in vitro
SEG Fligiel, J Varani, SC Datta, S Kang, GJ Fisher, JJ Voorhees
Journal of Investigative Dermatology 120 (5), 842-848, 2003
3182003
Troglitazone improves psoriasis and normalizes models of proliferative skin disease: ligands for peroxisome proliferator-activated receptor-γ inhibit keratinocyte proliferation
CN Ellis, J Varani, GJ Fisher, ME Zeigler, HA Pershadsingh, SC Benson, ...
Archives of Dermatology 136 (5), 609-616, 2000
2832000
Aberrant production of interleukin-8 and thrombospondin-1 by psoriatic keratinocytes mediates angiogenesis.
BJ Nickoloff, RS Mitra, J Varani, VM Dixit, PJ Polverini
The American journal of pathology 144 (4), 820, 1994
2801994
Role of ERK and JNK pathways in regulating cell motility and matrix metalloproteinase 9 production in growth factor‐stimulated human epidermal keratinocytes
ME Zeigler, Y Chi, T Schmidt, J Varani
Journal of cellular physiology 180 (2), 271-284, 1999
2721999
Extracellular calcium and calcium sensing receptor function in human colon carcinomas: promotion of E-cadherin expression and suppression of β-catenin/TCF activation
S Chakrabarty, V Radjendirane, H Appelman, J Varani
Cancer research 63 (1), 67-71, 2003
2672003
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Articles 1–20