Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation HMHG Albers, A Dong, LA van Meeteren, DA Egan, M Sunkara, ... Proceedings of the National Academy of Sciences 107 (16), 7257-7262, 2010 | 239 | 2010 |
Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer YY Zaytseva, PG Rychahou, P Gulhati, VA Elliott, WC Mustain, ... Cancer research 72 (6), 1504-1517, 2012 | 191 | 2012 |
The transporter Spns2 is required for secretion of lymph but not plasma sphingosine-1-phosphate A Mendoza, B Bréart, WD Ramos-Perez, LA Pitt, M Gobert, M Sunkara, ... Cell reports 2 (5), 1104-1110, 2012 | 174 | 2012 |
Binding of autotaxin to integrins localizes lysophosphatidic acid production to platelets and mammalian cells Z Fulkerson, T Wu, M Sunkara, C Vander Kooi, AJ Morris, SS Smyth Journal of Biological Chemistry 286 (40), 34654-34663, 2011 | 167 | 2011 |
Conditioning for hematopoietic transplantation activates the complement cascade and induces a proteolytic environment in bone marrow: a novel role for bioactive lipids and … CH Kim, W Wu, M Wysoczynski, A Abdel-Latif, M Sunkara, A Morris, ... Leukemia 26 (1), 106-116, 2012 | 150 | 2012 |
Facile Chemoenzymatic Strategies for the Synthesis and Utilization of S‐Adenosyl‐L‐Methionine Analogues S Singh, J Zhang, TD Huber, M Sunkara, K Hurley, RD Goff, G Wang, ... Angewandte Chemie International Edition 53 (15), 3965-3969, 2014 | 146 | 2014 |
Coplanar polychlorinated biphenyls impair glucose homeostasis in lean C57BL/6 mice and mitigate beneficial effects of weight loss on glucose homeostasis in obese mice NA Baker, M Karounos, V English, J Fang, Y Wei, A Stromberg, ... Environmental health perspectives 121 (1), 105-110, 2013 | 133 | 2013 |
Ceramide-1-phosphate regulates migration of multipotent stromal cells and endothelial progenitor cells—implications for tissue regeneration C Kim, G Schneider, A Abdel-Latif, K Mierzejewska, M Sunkara, ... Stem Cells 31 (3), 500-510, 2013 | 107 | 2013 |
Sphingosine 1-phosphate (S1P) regulates glucose-stimulated insulin secretion in pancreatic beta cells JC Stanford, AJ Morris, M Sunkara, GJ Popa, KL Larson, S Özcan Journal of Biological Chemistry 287 (16), 13457-13464, 2012 | 97 | 2012 |
Green tea diet decreases PCB 126-induced oxidative stress in mice by up-regulating antioxidant enzymes BJ Newsome, MC Petriello, SG Han, MO Murphy, KE Eske, M Sunkara, ... The Journal of nutritional biochemistry 25 (2), 126-135, 2014 | 92 | 2014 |
Mechanism of rapid elimination of lysophosphatidic acid and related lipids from the circulation of mice AK Salous, M Panchatcharam, M Sunkara, P Mueller, A Dong, Y Wang, ... Journal of lipid research 54 (10), 2775-2784, 2013 | 90 | 2013 |
Autotaxin and its product lysophosphatidic acid suppress brown adipose differentiation and promote diet-induced obesity in mice L Federico, H Ren, PA Mueller, T Wu, S Liu, J Popovic, EM Blalock, ... Molecular endocrinology 26 (5), 786-797, 2012 | 90 | 2012 |
A phosphatidic acid binding/nuclear localization motif determines lipin1 function in lipid metabolism and adipogenesis H Ren, L Federico, H Huang, M Sunkara, T Drennan, MA Frohman, ... Molecular biology of the cell 21 (18), 3171-3181, 2010 | 89 | 2010 |
Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling WJ Keune, J Hausmann, R Bolier, D Tolenaars, A Kremer, T Heidebrecht, ... Nature communications 7 (1), 11248, 2016 | 86 | 2016 |
Mice With Targeted Inactivation of Ppap2b in Endothelial and Hematopoietic Cells Display Enhanced Vascular Inflammation and Permeability M Panchatcharam, AK Salous, J Brandon, S Miriyala, J Wheeler, P Patil, ... Arteriosclerosis, thrombosis, and vascular biology 34 (4), 837-845, 2014 | 85 | 2014 |
Omega-3 fatty acid oxidation products prevent vascular endothelial cell activation by coplanar polychlorinated biphenyls Z Majkova, J Layne, M Sunkara, AJ Morris, M Toborek, B Hennig Toxicology and applied pharmacology 251 (1), 41-49, 2011 | 82 | 2011 |
Autophagy and oxidative stress in gliomas with IDH1 mutations MR Gilbert, Y Liu, J Neltner, H Pu, A Morris, M Sunkara, T Pittman, ... Acta neuropathologica 127, 221-233, 2014 | 81 | 2014 |
Bisphenol A increases atherosclerosis in pregnane X receptor‐humanized ApoE deficient mice Y Sui, SH Park, RN Helsley, M Sunkara, FJ Gonzalez, AJ Morris, C Zhou Journal of the American Heart Association 3 (2), e000492, 2014 | 77 | 2014 |
Epigallocatechin-gallate stimulates NF-E2-related factor and heme oxygenase-1 via caveolin-1 displacement Y Zheng, A Morris, M Sunkara, J Layne, M Toborek, B Hennig The Journal of nutritional biochemistry 23 (2), 163-168, 2012 | 76 | 2012 |
Discovery, biological evaluation, and structure− activity relationship of amidine based sphingosine kinase inhibitors TP Mathews, AJ Kennedy, Y Kharel, PC Kennedy, O Nicoara, M Sunkara, ... Journal of medicinal chemistry 53 (7), 2766-2778, 2010 | 75 | 2010 |