| Minimum information about a biosynthetic gene cluster MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ... Nature chemical biology 11 (9), 625-631, 2015 | 842 | 2015 |
| Strain prioritization and genome mining for enediyne natural products X Yan, H Ge, T Huang, Hindra, D Yang, Q Teng, I Crnovčić, X Li, ... MBio 7 (6), 10.1128/mbio. 02104-16, 2016 | 95 | 2016 |
| Genome neighborhood network reveals insights into enediyne biosynthesis and facilitates prediction and prioritization for discovery JD Rudolf, X Yan, B Shen Journal of Industrial Microbiology and Biotechnology 43 (2-3), 261-276, 2016 | 72 | 2016 |
| Stilbenes: Source plants, chemistry, biosynthesis, pharmacology, application and problems related to their clinical Application-A comprehensive review T Teka, L Zhang, X Ge, Y Li, L Han, X Yan Phytochemistry 197, 113128, 2022 | 71 | 2022 |
| Enediynes: exploration of microbial genomics to discover new anticancer drug leads B Shen, X Yan, T Huang, H Ge, D Yang, Q Teng, JD Rudolf, JR Lohman Bioorganic & medicinal chemistry letters 25 (1), 9-15, 2015 | 69 | 2015 |
| Genome Mining of Micromonospora yangpuensis DSM 45577 as a Producer of an Anthraquinone-Fused Enediyne X Yan, JJ Chen, A Adhikari, D Yang, I Crnovcic, N Wang, CY Chang, ... Organic Letters 19 (22), 6192-6195, 2017 | 61 | 2017 |
| Cloning and Heterologous Expression of Three Type II PKS Gene Clusters from Streptomyces bottropensis X Yan, K Probst, A Linnenbrink, M Arnold, T Paululat, A Zeeck, ... ChemBioChem 13 (2), 224-230, 2012 | 57 | 2012 |
| Signal enhancing strategies in aptasensors for the detection of small molecular contaminants by nanomaterials and nucleic acid amplification N Zhang, J Li, B Liu, D Zhang, C Zhang, Y Guo, X Chu, W Wang, H Wang, ... Talanta 236, 122866, 2022 | 45 | 2022 |
| Eucommia ulmoides leaf extract alters gut microbiota composition, enhances short‐chain fatty acids production, and ameliorates osteoporosis in the senescence … X Zhao, Y Wang, Z Nie, L Han, X Zhong, X Yan, X Gao Food science & nutrition 8 (9), 4897-4906, 2020 | 39 | 2020 |
| Comparative studies of the biosynthetic gene clusters for anthraquinone-fused enediynes shedding light into the tailoring steps of tiancimycin biosynthesis X Yan, JJ Chen, A Adhikari, CN Teijaro, H Ge, I Crnovcic, CY Chang, ... Organic Letters 20 (18), 5918-5921, 2018 | 39 | 2018 |
| Ribosome engineering and fermentation optimization leads to overproduction of tiancimycin A, a new enediyne natural product from Streptomyces sp. CB03234 L Liu, J Pan, Z Wang, X Yan, D Yang, X Zhu, B Shen, Y Duan, Y Huang Journal of Industrial Microbiology and Biotechnology 45 (3), 141-151, 2018 | 37 | 2018 |
| Streptomycin‐induced ribosome engineering complemented with fermentation optimization for enhanced production of 10‐membered enediynes tiancimycin‐A and tiancimycin‐D Z Zhuang, C Jiang, F Zhang, R Huang, L Yi, Y Huang, X Yan, Y Duan, ... Biotechnology and Bioengineering 116 (6), 1304-1314, 2019 | 31 | 2019 |
| Huanglongmycin A-C, Cytotoxic Polyketides Biosynthesized by a Putative Type II Polyketide Synthase From Streptomyces sp. CB09001 L Jiang, H Pu, J Xiang, M Su, X Yan, D Yang, X Zhu, B Shen, Y Duan, ... Frontiers in Chemistry 6, 254, 2018 | 27 | 2018 |
| Yangpumicins F and G, Enediyne Congeners from Micromonospora yangpuensis DSM 45577 Z Wang, Z Wen, L Liu, X Zhu, B Shen, X Yan, Y Duan, Y Huang Journal of natural products 82 (9), 2483-2488, 2019 | 25 | 2019 |
| Discovery of the tiancilactone antibiotics by genome mining of atypical bacterial type II diterpene synthases LB Dong, JD Rudolf, MR Deng, X Yan, B Shen ChemBioChem 19 (16), 1727-1733, 2018 | 25 | 2018 |
| The discovery and development of microbial bleomycin analogues J Kong, L Yi, Y Xiong, Y Huang, D Yang, X Yan, B Shen, Y Duan, X Zhu Applied microbiology and biotechnology 102, 6791-6798, 2018 | 24 | 2018 |
| Resistance to enediyne antitumor antibiotics by sequestration CY Chang, X Yan, I Crnovcic, T Annaval, C Chang, B Nocek, JD Rudolf, ... Cell chemical biology 25 (9), 1075-1085. e4, 2018 | 23 | 2018 |
| Anthraquinone-fused enediynes: discovery, biosynthesis and development X Yan Natural Product Reports 39 (3), 703-728, 2022 | 21 | 2022 |
| Characterization of TnmH as an O-Methyltransferase Revealing Insights into Tiancimycin Biosynthesis and Enabling a Biocatalytic Strategy To Prepare Antibody … A Adhikari, CN Teijaro, X Yan, CY Chang, C Gui, YC Liu, I Crnovcic, ... Journal of medicinal chemistry 63 (15), 8432-8441, 2020 | 19 | 2020 |
| Crystal structures of SgcE6 and SgcC, the two-component monooxygenase that catalyzes hydroxylation of a carrier protein-tethered substrate during the biosynthesis of the … CY Chang, JR Lohman, H Cao, K Tan, JD Rudolf, M Ma, W Xu, ... Biochemistry 55 (36), 5142-5154, 2016 | 18 | 2016 |
Ben ShenThe Scripps Research InstituteVerified email at scripps.edu
