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Ewoud Ewing
Ewoud Ewing
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Competitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells
H Lund, M Pieber, R Parsa, J Han, D Grommisch, E Ewing, L Kular, ...
Nature communications 9 (1), 1-13, 2018
1832018
DNA methylation as a mediator of HLA-DRB1* 15: 01 and a protective variant in multiple sclerosis
L Kular, Y Liu, S Ruhrmann, G Zheleznyakova, F Marabita, ...
Nature communications 9 (1), 1-15, 2018
1802018
Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis associates with ROS pathway in monocytes
KE Carlström, E Ewing, M Granqvist, A Gyllenberg, S Aeinehband, ...
Nature communications 10 (1), 1-13, 2019
1202019
Microglial autophagy–associated phagocytosis is essential for recovery from neuroinflammation
R Berglund, AO Guerreiro-Cacais, MZ Adzemovic, M Zeitelhofer, H Lund, ...
Science immunology 5 (52), eabb5077, 2020
1022020
Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-β signaling
H Lund, M Pieber, R Parsa, D Grommisch, E Ewing, L Kular, J Han, K Zhu, ...
Nature immunology 19 (5), 1-7, 2018
672018
Combining evidence from four immune cell types identifies DNA methylation patterns that implicate functionally distinct pathways during Multiple Sclerosis progression
E Ewing, L Kular, SJ Fernandes, N Karathanasis, V Lagani, S Ruhrmann, ...
EBioMedicine 43, 411-423, 2019
552019
Epigenetic research in multiple sclerosis: progress, challenges, and opportunities
GY Zheleznyakova, E Piket, F Marabita, M Pahlevan Kakhki, E Ewing, ...
Physiological genomics 49 (9), 447-461, 2017
472017
Hypermethylation of MIR21 in CD4+ T cells from patients with relapsing-remitting multiple sclerosis associates with lower miRNA-21 levels and concomitant up …
S Ruhrmann, E Ewing, E Piket, L Kular, JC Cetrulo Lorenzi, SJ Fernandes, ...
Multiple Sclerosis Journal 24 (10), 1288-1300, 2018
452018
Gsta4 controls apoptosis of differentiating adult oligodendrocytes during homeostasis and remyelination via the mitochondria-associated Fas-Casp8-Bid-axis
KE Carlström, K Zhu, E Ewing, IE Krabbendam, RA Harris, AM Falcão, ...
Nature communications 11 (1), 1-13, 2020
392020
Epigenetic alterations associated with early prenatal dexamethasone treatment
L Karlsson, M Barbaro, E Ewing, D Gomez-Cabrero, S Lajic
Journal of the Endocrine Society 3 (1), 250-263, 2019
382019
STATegra: multi-omics data integration–a conceptual scheme with a bioinformatics pipeline
N Planell, V Lagani, P Sebastian-Leon, F van der Kloet, E Ewing, ...
Frontiers in genetics 12, 620453, 2021
302021
Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis
L Kular, M Needhamsen, MZ Adzemovic, T Kramarova, D Gomez-Cabrero, ...
Clinical epigenetics 11 (1), 1-20, 2019
302019
Usability of human Infinium MethylationEPIC BeadChip for mouse DNA methylation studies
M Needhamsen, E Ewing, H Lund, D Gomez-Cabrero, RA Harris, L Kular, ...
BMC bioinformatics 18 (1), 1-9, 2017
282017
DNA methylation changes in glial cells of the normal-appearing white matter in Multiple Sclerosis patients
L Kular, E Ewing, M Needhamsen, M Pahlevan Kakhki, R Covacu, ...
Epigenetics, 1-20, 2022
172022
Non-parametric combination analysis of multiple data types enables detection of novel regulatory mechanisms in T cells of multiple sclerosis patients
SJ Fernandes, H Morikawa, E Ewing, S Ruhrmann, RN Joshi, V Lagani, ...
Scientific reports 9 (1), 1-12, 2019
162019
Epigenetic clock indicates accelerated ageing in glial cells of progressive Multiple Sclerosis patients
L Kular, D Klose, A Urdánoz-Casado, E Ewing, N Planell, ...
Frontiers in Aging Neuroscience, 880, 0
12
GeneSetCluster: a tool for summarizing and integrating gene-set analysis results
E Ewing, N Planell-Picola, M Jagodic, D Gomez-Cabrero
BMC bioinformatics 21 (1), 1-7, 2020
112020
DNA methylation as a mediator of HLA-DRB1415: 01 and a protective variant in multiple sclerosis. Nat Commun. 2018; 9 (1): 2397
L Kular, Y Liu, S Ruhrmann, G Zheleznyakova, F Marabita, ...
5
Transcriptomic Profiling Reveals That HMGB1 Induces Macrophage Polarization Different from Classical M1
H Qu, R Heinbäck, H Salo, E Ewing, A Espinosa, C Aulin, ...
Biomolecules 12 (6), 779, 2022
42022
Neurofilament light chain as a marker for cortical atrophy in multiple sclerosis without radiological signs of disease activity
BV Ineichen, T Moridi, E Ewing, R Ouellette, A Manouchehrinia, ...
Journal of internal medicine 290 (2), 473-476, 2021
42021
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