| The ontogeny of human drug-metabolizing enzymes: phase I oxidative enzymes RN Hines, DG McCarver Journal of Pharmacology and Experimental Therapeutics 300 (2), 355-360, 2002 | 450 | 2002 |
| The ontogeny of human drug-metabolizing enzymes: phase II conjugation enzymes and regulatory mechanisms DG McCarver, RN Hines Journal of Pharmacology and Experimental Therapeutics 300 (2), 361-366, 2002 | 444 | 2002 |
| Developmental expression of the major human hepatic CYP3A enzymes JC Stevens, RN Hines, C Gu, SB Koukouritaki, JR Manro, PJ Tandler, ... Journal of Pharmacology and Experimental Therapeutics 307 (2), 573-582, 2003 | 416 | 2003 |
| Expression of CYP1A1 gene in patients with lung cancer: evidence for cigarette smoke-induced gene expression in normal lung tissue and for altered gene regulation in primary … TL McLemore, S Adelberg, MC Liu, NA McMahon, SJ Yu, WC Hubbard, ... JNCI: Journal of the National Cancer Institute 82 (16), 1333-1339, 1990 | 411 | 1990 |
| The ontogeny of drug metabolism enzymes and implications for adverse drug events RN Hines Pharmacology & Therapeutics 118 (2), 250-267, 2008 | 400 | 2008 |
| Developmental expression of human hepatic CYP2C9 and CYP2C19 SB Koukouritaki, JR Manro, SA Marsh, JC Stevens, AE Rettie, ... Journal of Pharmacology and Experimental Therapeutics 308 (3), 965-974, 2004 | 356 | 2004 |
| Human hepatic flavin-containing monooxygenases 1 (FMO1) and 3 (FMO3) developmental expression SB Koukouritaki, P Simpson, CK Yeung, AE Rettie, RN Hines Pediatric research 51 (2), 236-243, 2002 | 295 | 2002 |
| A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities MP Lawton, JR Cashman, T Cresteil, CT Dolphin, AA Elfarra, RN Hines, ... Archives of Biochemistry and Biophysics 308 (1), 254-257, 1994 | 264 | 1994 |
| Ontogeny of human hepatic cytochromes P450 RN Hines Journal of biochemical and molecular toxicology 21 (4), 169-175, 2007 | 263 | 2007 |
| Identification of multiple regulatory elements on the human cytochrome P450IA1 gene RN Hines, JM Mathis, CS Jacob Carcinogenesis 9 (9), 1599-1605, 1988 | 194 | 1988 |
| A Genetic Polymorphism in the Regulatory Sequences of Human CYP2E1: Association with Increased Chlorzoxazone Hydroxylation in the Presence of Obesity and Ethanol Intake DG McCarver, R Byun, RN Hines, M Hichme, W Wegenek Toxicology and applied pharmacology 152 (1), 276-281, 1998 | 193 | 1998 |
| Human hepatic CYP2E1 expression during development EK Johnsrud, SB Koukouritaki, K Divakaran, LL Brunengraber, RN Hines, ... Journal of Pharmacology and Experimental Therapeutics 307 (1), 402-407, 2003 | 191 | 2003 |
| Hepatic differentiation of amniotic epithelial cells F Marongiu, R Gramignoli, K Dorko, T Miki, AR Ranade, M Paola Serra, ... Hepatology 53 (5), 1719-1729, 2011 | 188 | 2011 |
| Developmental expression of drug metabolizing enzymes: impact on disposition in neonates and young children RN Hines International journal of pharmaceutics 452 (1-2), 3-7, 2013 | 171 | 2013 |
| The mammalian flavin-containing monooxygenases: molecular characterization and regulation of expression RN Hines, JR Cashman, RM Philpot, DE Williams, DM Ziegler Toxicology and applied pharmacology 125 (1), 1-6, 1994 | 160 | 1994 |
| Developmental changes in human liver CYP2D6 expression JC Stevens, SA Marsh, MJ Zaya, KJ Regina, K Divakaran, M Le, ... Drug metabolism and disposition 36 (8), 1587-1593, 2008 | 157 | 2008 |
| A tiered approach to life stages testing for agricultural chemical safety assessment RL Cooper, JC Lamb IV, SM Barlow, K Bentley, AM Brady, NG Doerrer, ... Critical Reviews in Toxicology 36 (1), 69-98, 2006 | 148 | 2006 |
| Developmental expression of aryl, estrogen, and hydroxysteroid sulfotransferases in pre-and postnatal human liver Z Duanmu, A Weckle, SB Koukouritaki, RN Hines, JL Falany, CN Falany, ... Journal of Pharmacology and Experimental Therapeutics 316 (3), 1310-1317, 2006 | 131 | 2006 |
| Restoration of aryl hydrocarbon (Ah) responsiveness in MDA-MB-231 human breast cancer cells by transient expression of the estrogen receptor JS Thomsen, X Wang, RN Hines, S Safe Carcinogenesis 15 (5), 933-937, 1994 | 126 | 1994 |
| Risk assessment in the 21st century: roadmap and matrix MR Embry, AN Bachman, DR Bell, AR Boobis, SM Cohen, M Dellarco, ... Critical reviews in toxicology 44 (sup3), 6-16, 2014 | 122 | 2014 |
David WilliamsProfessor of Environmental and Molecular Toxicology, Oregon State UniversityVerified email at oregonstate.edu
