Emanuela Marina Bruscia, PhD
Emanuela Marina Bruscia, PhD
Associate Professor of Pediatrics, Yale University
Verified email at
Cited by
Cited by
Plasticity of bone marrow–derived stem cells
JE Grove, E Bruscia, DS Krause
Stem cells 22 (4), 487-500, 2004
Lack of a fusion requirement for development of bone marrow-derived epithelia
RG Harris, EL Herzog, EM Bruscia, JE Grove, JS Van Arnam, DS Krause
Science 305 (5680), 90-93, 2004
Cellular innate immunity: an old game with new players
G Gasteiger, A D'osualdo, DA Schubert, A Weber, EM Bruscia, D Hartl
Journal of innate immunity 9 (2), 111-125, 2017
Innate immunity in cystic fibrosis lung disease
D Hartl, A Gaggar, E Bruscia, A Hector, V Marcos, A Jung, C Greene, ...
Journal of Cystic Fibrosis 11 (5), 363-382, 2012
Macrophages directly contribute to the exaggerated inflammatory response in cystic fibrosis transmembrane conductance regulator−/− mice
EM Bruscia, PX Zhang, E Ferreira, C Caputo, JW Emerson, D Tuck, ...
American journal of respiratory cell and molecular biology 40 (3), 295-304, 2009
Isolation of CF cell lines corrected at ΔF508-CFTR locus by SFHR-mediated targeting
E Bruscia, F Sangiuolo, P Sinibaldi, KK Goncz, G Novelli, DC Gruenert
Gene therapy 9 (11), 683-685, 2002
Cystic fibrosis lung immunity: the role of the macrophage
EM Bruscia, TL Bonfield
Journal of innate immunity 8 (6), 550-563, 2016
Abnormal trafficking and degradation of TLR4 underlie the elevated inflammatory response in cystic fibrosis
EM Bruscia, PX Zhang, A Satoh, C Caputo, R Medzhitov, A Shenoy, ...
The Journal of Immunology 186 (12), 6990-6998, 2011
Sequence-specific modification of genomic DNA by small DNA fragments
DC Gruenert, E Bruscia, G Novelli, A Colosimo, B Dallapiccola, ...
The Journal of clinical investigation 112 (5), 637-641, 2003
Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammation
P Zhang, J Cheng, S Zou, AD D'Souza, JL Koff, J Lu, PJ Lee, DS Krause, ...
Nature communications 6 (1), 6221, 2015
Innate and adaptive immunity in cystic fibrosis
EM Bruscia, TL Bonfield
Clinics in chest medicine 37 (1), 17-29, 2016
Assessment of cystic fibrosis transmembrane conductance regulator (CFTR) activity in CFTR-null mice after bone marrow transplantation
EM Bruscia, JE Price, EC Cheng, S Weiner, C Caputo, EC Ferreira, ...
Proceedings of the National Academy of Sciences 103 (8), 2965-2970, 2006
Role for MKL1 in megakaryocytic maturation
E Cheng, Q Luo, EM Bruscia, MJ Renda, JA Troy, SA Massaro, D Tuck, ...
Blood, The Journal of the American Society of Hematology 113 (12), 2826-2834, 2009
Very small embryonic-like stem cells from the murine bone marrow differentiate into epithelial cells of the lung
SH Kassmer, H Jin, PX Zhang, EM Bruscia, K Heydari, JH Lee, CF Kim, ...
Stem Cells 31 (12), 2759-2766, 2013
A highly efficient and faithful MDS patient-derived xenotransplantation model for pre-clinical studies
Y Song, A Rongvaux, A Taylor, T Jiang, T Tebaldi, K Balasubramanian, ...
Nature communications 10 (1), 366, 2019
The carbon monoxide releasing molecule CORM-2 attenuates Pseudomonas aeruginosa biofilm formation
TS Murray, C Okegbe, Y Gao, BI Kazmierczak, R Motterlini, LEP Dietrich, ...
PLoS One 7 (4), e35499, 2012
Engraftment of donor‐derived epithelial cells in multiple organs following bone marrow transplantation into newborn mice
EM Bruscia, EC Ziegler, JE Price, S Weiner, ME Egan, DS Krause
Stem cells 24 (10), 2299-2308, 2006
Single-cell transcriptional archetypes of airway inflammation in cystic fibrosis
JC Schupp, S Khanal, JL Gomez, M Sauler, TS Adams, GL Chupp, X Yan, ...
American journal of respiratory and critical care medicine 202 (10), 1419-1429, 2020
Reduced caveolin-1 promotes hyperinflammation due to abnormal heme oxygenase-1 localization in lipopolysaccharide-challenged macrophages with dysfunctional cystic fibrosis …
PX Zhang, TS Murray, VR Villella, E Ferrari, S Esposito, A D'Souza, ...
The Journal of Immunology 190 (10), 5196-5206, 2013
SRF is required for neutrophil migration in response to inflammation
A Taylor, W Tang, EM Bruscia, PX Zhang, A Lin, P Gaines, D Wu, ...
Blood, The Journal of the American Society of Hematology 123 (19), 3027-3036, 2014
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