| The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues. G Giannini, A Conti, S Mammarella, M Scrobogna, V Sorrentino The Journal of cell biology 128 (5), 893-904, 1995 | 674 | 1995 |
| Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer SE Bojesen, KA Pooley, SE Johnatty, J Beesley, K Michailidou, JP Tyrer, ... Nature genetics 45 (4), 371-384, 2013 | 646 | 2013 |
| Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer TR Rebbeck, N Mitra, F Wan, OM Sinilnikova, S Healey, L McGuffog, ... Jama 313 (13), 1347-1361, 2015 | 547 | 2015 |
| Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination LD Marcotullio, E Ferretti, A Greco, E De Smaele, A Po, MA Sico, ... Nature cell biology 8 (12), 1415-1423, 2006 | 346 | 2006 |
| Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers KB Kuchenbaecker, L McGuffog, D Barrowdale, A Lee, P Soucy, J Dennis, ... JNCI: Journal of the National Cancer Institute 109 (7), djw302, 2017 | 316 | 2017 |
| Modulation of the heparanase-inhibiting activity of heparin through selective desulfation, graded N-acetylation, and glycol splitting A Naggi, B Casu, M Perez, G Torri, G Cassinelli, S Penco, C Pisano, ... Journal of Biological Chemistry 280 (13), 12103-12113, 2005 | 294 | 2005 |
| Expression of a Ryanodine Receptor-Ca2+ Channel that is Regulated by TGF-β G Giannini, E Clementi, R Ceci, G Marziali, V Sorrentino Science 257 (5066), 91-94, 1992 | 292 | 1992 |
| Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations TR Rebbeck, TM Friebel, E Friedman, U Hamann, D Huo, A Kwong, ... Human mutation 39 (5), 593-620, 2018 | 289 | 2018 |
| Human MRE11 is inactivated in mismatch repair‐deficient cancers G Giannini, E Ristori, F Cerignoli, C Rinaldi, M Zani, A Viel, L Ottini, ... EMBO reports, 2002 | 212 | 2002 |
| A specific mutational signature associated with DNA 8-oxoguanine persistence in MUTYH-defective colorectal cancer A Viel, A Bruselles, E Meccia, M Fornasarig, M Quaia, V Canzonieri, ... EBioMedicine 20, 39-49, 2017 | 203 | 2017 |
| Histone deacetylase inhibitors in the treatment of cancer: overview and perspectives G Giannini, W Cabri, C Fattorusso, M Rodriquez Future medicinal chemistry 4 (11), 1439-1460, 2012 | 203 | 2012 |
| Heterocyclic and phenyl double-bond-locked combretastatin analogues possessing potent apoptosis-inducing activity in HL60 and in MDR cell lines D Simoni, G Grisolia, G Giannini, M Roberti, R Rondanin, L Piccagli, ... Journal of medicinal chemistry 48 (3), 723-736, 2005 | 195 | 2005 |
| The role of peroxiredoxins in cancer A Nicolussi, S D'inzeo, C Capalbo, G Giannini, A Coppa Molecular and clinical oncology 6 (2), 139-153, 2017 | 182 | 2017 |
| Heparanase: a rainbow pharmacological target associated to multiple pathologies including rare diseases S Rivara, FM Milazzo, G Giannini Future medicinal chemistry 8 (6), 647-680, 2016 | 176 | 2016 |
| MiR-128 up-regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness C Evangelisti, M Florian, I Massimi, C Dominici, G Giannini, S Galardi, ... The FASEB Journal 23 (12), 4276-4287, 2009 | 176 | 2009 |
| Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2 V Silvestri, D Barrowdale, AM Mulligan, SL Neuhausen, S Fox, BY Karlan, ... Breast Cancer Research 18, 1-13, 2016 | 145 | 2016 |
| The Early Growth Response Gene EGR-1 Behaves as a Suppressor Gene That Is Down-Regulated Independent of ARF/Mdm2 but not p53 Alterations in Fresh … A Calogero, A Arcella, G De Gregorio, A Porcellini, D Mercola, C Liu, ... Clinical Cancer Research 7 (9), 2788-2796, 2001 | 145 | 2001 |
| Relative increase of T cells expressing the gamma/delta rather than the alpha/beta receptor in ataxia-telangiectasia M Carbonari, M Cherchi, R Paganelli, G Giannini, E Galli, C Gaetano, ... New England Journal of Medicine 322 (2), 73-76, 1990 | 139 | 1990 |
| Mutations of an intronic repeat induce impaired MRE11 expression in primary human cancer with microsatellite instability G Giannini, C Rinaldi, E Ristori, MI Ambrosini, F Cerignoli, A Viel, E Bidoli, ... Oncogene 23 (15), 2640-2647, 2004 | 135 | 2004 |
| Novel combretastatin analogues endowed with antitumor activity D Simoni, R Romagnoli, R Baruchello, R Rondanin, M Rizzi, MG Pavani, ... Journal of medicinal chemistry 49 (11), 3143-3152, 2006 | 134 | 2006 |
