متابعة
Rab Prinjha
Rab Prinjha
GlaxoSmithkline
بريد إلكتروني تم التحقق منه على gsk.com
عنوان
عدد مرات الاقتباسات
عدد مرات الاقتباسات
السنة
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia‏
MA Dawson, RK Prinjha, A Dittmann, G Giotopoulos, M Bantscheff, ...‏
Nature 478 (7370), 529-533, 2011‏
16972011
Suppression of inflammation by a synthetic histone mimic‏
E Nicodeme, KL Jeffrey, U Schaefer, S Beinke, S Dewell, C Chung, ...‏
Nature 468 (7327), 1119-1123, 2010‏
16762010
Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways‏
JP Cogswell, J Ward, IA Taylor, M Waters, Y Shi, B Cannon, K Kelnar, ...‏
Journal of Alzheimer's disease 14 (1), 27-41, 2008‏
10932008
Inhibitor of neurite outgrowth in humans‏
WFS Prinjha R, Moore SE, Vinson M, Blake S, Morrow R, Christie G ...‏
Nature 403, 383-4, 2000‏
8772000
Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription‏
MU Kaikkonen, NJ Spann, S Heinz, CE Romanoski, KA Allison, ...‏
Molecular cell 51 (3), 310-325, 2013‏
7062013
Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation‏
HD Lewis, J Liddle, JE Coote, SJ Atkinson, MD Barker, BD Bax, KL Bicker, ...‏
Nature chemical biology 11 (3), 189-191, 2015‏
6352015
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease‏
H Li, S Wetten, L Li, PLS Jean, R Upmanyu, L Surh, D Hosford, ...‏
Archives of neurology 65 (1), 45-53, 2008‏
5942008
Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis‏
SE Baranzini, J Wang, RA Gibson, N Galwey, Y Naegelin, F Barkhof, ...‏
Human molecular genetics 18 (4), 767-778, 2009‏
5732009
BET inhibitor resistance emerges from leukaemia stem cells‏
CY Fong, O Gilan, EYN Lam, AF Rubin, S Ftouni, D Tyler, K Stanley, ...‏
Nature 525 (7570), 538-542, 2015‏
5142015
Neuropilin-2 is required in vivo for selective axon guidance responses to secreted semaphorins‏
RJ Giger, JF Cloutier, A Sahay, RK Prinjha, DV Levengood, SE Moore, ...‏
Neuron 25 (1), 29-41, 2000‏
5102000
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer‏
ML Burr, CE Sparbier, KL Chan, YC Chan, A Kersbergen, EYN Lam, ...‏
Cancer cell 36 (4), 385-401. e8, 2019‏
4312019
Discovery and characterization of small molecule inhibitors of the BET family bromodomains‏
C Chung, H Coste, JH White, O Mirguet, J Wilde, RL Gosmini, C Delves, ...‏
Journal of medicinal chemistry 54 (11), 3827-3838, 2011‏
4252011
Broadly neutralizing antibodies and viral inducers decrease rebound from HIV-1 latent reservoirs in humanized mice‏
A Halper-Stromberg, CL Lu, F Klein, JA Horwitz, S Bournazos, L Nogueira, ...‏
Cell 158 (5), 989-999, 2014‏
4152014
Cloning and functional expression of a human orthologue of rat vanilloid receptor-1‏
P Hayes, HJ Meadows, MJ Gunthorpe, MH Harries, MD Duckworth, ...‏
Pain 88 (2), 205-215, 2000‏
3872000
Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia‏
P Ntziachristos, A Tsirigos, GG Welstead, T Trimarchi, S Bakogianni, L Xu, ...‏
Nature 514 (7523), 513-517, 2014‏
3772014
Discovery of epigenetic regulator I-BET762: lead optimization to afford a clinical candidate inhibitor of the BET bromodomains‏
O Mirguet, R Gosmini, J Toum, CA Clément, M Barnathan, JM Brusq, ...‏
Journal of medicinal chemistry 56 (19), 7501-7515, 2013‏
3452013
Suppression of the antiviral response by an influenza histone mimic‏
I Marazzi, JSY Ho, J Kim, B Manicassamy, S Dewell, RA Albrecht, ...‏
Nature 483 (7390), 428-433, 2012‏
3282012
Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation‏
O Gilan, I Rioja, K Knezevic, MJ Bell, MM Yeung, NR Harker, EYN Lam, ...‏
Science 368 (6489), 387-394, 2020‏
3012020
Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling‏
D Levy, AJ Kuo, Y Chang, U Schaefer, C Kitson, P Cheung, A Espejo, ...‏
Nature immunology 12 (1), 29, 2011‏
2852011
Place your BETs: the therapeutic potential of bromodomains‏
RK Prinjha, J Witherington, K Lee‏
Trends in pharmacological sciences 33 (3), 146-153, 2012‏
2782012
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مقالات 1–20