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Amberley D Stephens
Amberley D Stephens
Verified email at astrazeneca.com
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Cited by
Cited by
Year
C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction
J Lautenschläger, AD Stephens, G Fusco, F Ströhl, N Curry, ...
Nature communications 9 (1), 712, 2018
2772018
Structural basis of synaptic vesicle assembly promoted by α-synuclein
G Fusco, T Pape, AD Stephens, P Mahou, AR Costa, CF Kaminski, ...
Nature communications 7 (1), 12563, 2016
2432016
Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity
AD Stephens, M Zacharopoulou, R Moons, G Fusco, N Seetaloo, A Chiki, ...
Nature communications 11 (1), 2820, 2020
1112020
The cellular environment affects monomeric α-synuclein structure
AD Stephens, M Zacharopoulou, GSK Schierle
Trends in biochemical sciences 44 (5), 453-466, 2019
732019
Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in Caenorhabditis elegans
C Huang, S Wagner-Valladolid, AD Stephens, R Jung, C Poudel, ...
Elife 8, e43059, 2019
572019
Different structural conformers of monomeric alpha-synuclein identified after lyophilising and freezing
AD Stephens, N Nespovitaya, M Zacharopoulou, CF Kaminski, JJ Phillips, ...
Analytical chemistry, 2018
392018
Intramitochondrial proteostasis is directly coupled to α-synuclein and amyloid β1-42 pathologies
J Lautenschläger, S Wagner-Valladolid, AD Stephens, ...
Journal of Biological Chemistry 295 (30), 10138-10152, 2020
292020
Short hydrogen bonds enhance nonaromatic protein-related fluorescence
AD Stephens, MN Qaisrani, MT Ruggiero, G Díaz Mirón, UN Morzan, ...
Proceedings of the National Academy of Sciences 118 (21), e2020389118, 2021
272021
The role of water in amyloid aggregation kinetics
AD Stephens, GSK Schierle
Current opinion in structural biology 58, 115-123, 2019
272019
Observation of high-temperature macromolecular confinement in lyophilised protein formulations using terahertz spectroscopy
TA Shmool, PJ Woodhams, M Leutzsch, AD Stephens, MU Gaimann, ...
International journal of pharmaceutics: X 1, 100022, 2019
242019
Phylogeographic diversity and mosaicism of the Helicobacter pylori tfs integrative and conjugative elements
RM Delahay, NJ Croxall, AD Stephens
Mobile DNA 9, 1-20, 2018
212018
Intracellular Aβ42 aggregation leads to cellular thermogenesis
CW Chung, AD Stephens, T Konno, E Ward, E Avezov, CF Kaminski, ...
Journal of the American Chemical Society 144 (22), 10034-10041, 2022
172022
Purification of recombinant α-Synuclein: a comparison of commonly used protocols
A Stephens, D Matak-Vinkovic, A Fernandez-Villegas, ...
Biochemistry 59 (48), 4563-4572, 2020
172020
Low energy optical excitations as an indicator of structural changes initiated at the termini of amyloid proteins
KH Jong, YT Azar, L Grisanti, AD Stephens, STE Jones, D Credgington, ...
Physical Chemistry Chemical Physics 21 (43), 23931-23942, 2019
162019
Millisecond hydrogen/deuterium-exchange mass spectrometry approach to correlate local structure and aggregation in α-synuclein
N Seetaloo, M Zacharopoulou, AD Stephens, GS Kaminski Schierle, ...
Analytical Chemistry 94 (48), 16711-16719, 2022
112022
Decreased water mobility contributes to increased α‐synuclein aggregation
AD Stephens, J Kölbel, R Moons, CW Chung, MT Ruggiero, N Mahmoudi, ...
Angewandte Chemie International Edition 62 (7), e202212063, 2023
102023
Label-free characterisation of amyloids and alpha-Synuclein polymorphs by exploiting their intrinsic fluorescence property
CW Chung, AD Stephens, E Ward, Y Feng, MJ Davis, CF Kaminski, ...
Analytical Chemistry 94 (13), 5367–5374, 2022
102022
Fast Purification of Recombinant Monomeric Amyloid‑β from E. coli and Amyloid-β-mCherry Aggregates from Mammalian Cells
A Stephens, M Lu, A Fernandez-Villegas, G Kaminski Schierle
ACS Chemical Neuroscience 11, 3204-3213, 2020
82020
TE; Credgington, D.; Kaminski Schierle, GS; Hassanali, A. Low energy optical excitations as an indicator of structural changes initiated at the termini of amyloid proteins
KH Jong, YT Azar, L Grisanti, AD Stephens, S Jones
Phys. Chem. Chem. Phys 21 (43), 23931-23942, 2019
62019
The role of water mobility in protein misfolding
AD Stephens, J Kölbel, R Moons, MT Ruggerio, N Mahmoudi, TA Shmool, ...
bioRxiv, 2021.01. 06.425575, 2021
52021
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Articles 1–20