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Mohamed Helal
Mohamed Helal
Verified email at zewailcity.edu.eg
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Cited by
Cited by
Year
Molecular basis of the potential interaction of SARS-CoV-2 spike protein to CD147 in COVID-19 associated-lymphopenia
MA Helal, S Shouman, A Abdelwaly, AO Elmehrath, M Essawy, SM Sayed, ...
Journal of Biomolecular Structure and Dynamics 40 (3), 1109-1119, 2022
822022
Design, synthesis, and biological evaluation of novel thiazolidinediones as PPARγ/FFAR1 dual agonists
KM Darwish, I Salama, S Mostafa, MS Gomaa, MA Helal
European Journal of Medicinal Chemistry 109, 157-172, 2016
642016
Interaction of nanoparticles with biological macromolecules: A review of molecular docking studies
AS Abdelsattar, A Dawoud, MA Helal
Nanotoxicology 15 (1), 66-95, 2021
632021
VALIDATED RP-HPLC METHOD FOR SIMULTANEOUS DETERMINATION OF CANAGLIFLOZIN, DAPAGLIFLOZIN, EMPAGLIFLOZIN AND METFORMIN.
GA Khalil, I Salama, MS Gomaa, MA Helal
International Journal of Pharmaceutical, Chemical & Biological Sciences 8 (1), 2018
482018
Recent advances in the development of sigma receptor ligands as cytotoxic agents: A medicinal chemistry perspective
AN Fallica, V Pittalà, MN Modica, L Salerno, G Romeo, A Marrazzo, ...
Journal of Medicinal Chemistry 64 (12), 7926-7962, 2021
402021
Selective kappa opioid antagonists for treatment of addiction, are we there yet?
MA Helal, ES Habib, AG Chittiboyina
European Journal of Medicinal Chemistry 141, 632-647, 2017
362017
Design, synthesis, and development of novel guaianolide-endoperoxides as potential antimalarial agents
L Sun, F Shah, MA Helal, Y Wu, Y Pedduri, AG Chittiboyina, J Gut, ...
Journal of medicinal chemistry 53 (21), 7864-7868, 2010
342010
Development and validation of an HPLC-UV method for simultaneous determination of sildenafil and tramadol in biological fluids: Application to drug-drug interaction study
HE Dahshan, MA Helal, SM Mostafa, MS Elgawish
Journal of pharmaceutical and biomedical analysis 168, 201-208, 2019
302019
Synthesis, biological evaluation, and molecular docking investigation of benzhydrol-and indole-based dual PPAR-γ/FFAR1 agonists
KM Darwish, I Salama, S Mostafa, MS Gomaa, ES Khafagy, MA Helal
Bioorganic & Medicinal Chemistry Letters 28 (9), 1595-1602, 2018
272018
Novel pyrazoles and pyrazolo [1, 2-a] pyridazines as selective COX-2 inhibitors; Ultrasound-assisted synthesis, biological evaluation, and DFT calculations
N Ghareb, HA Elshihawy, MM Abdel-Daim, MA Helal
Bioorganic & Medicinal Chemistry Letters 27 (11), 2377-2383, 2017
272017
Cytotoxic activity evaluation and molecular docking study of phenolic derivatives from Achillea fragrantissima (Forssk.) growing in Egypt
BM Awad, ES Habib, AK Ibrahim, AS Wanas, MM Radwan, MA Helal, ...
Medicinal Chemistry Research 26, 2065-2073, 2017
252017
Design and Synthesis of Imidazole and Triazole Pyrazoles as Mycobacterium Tuberculosis CYP121A1 Inhibitors
SM Kishk, KJ McLean, S Sood, D Smith, JWD Evans, MA Helal, ...
ChemistryOpen 8 (7), 995-1011, 2019
232019
Design, synthesis, and enzyme kinetics of novel benzimidazole and quinoxaline derivatives as methionine synthase inhibitors
H Elshihawy, MA Helal, M Said, MA Hammad
Bioorganic & Medicinal Chemistry 22 (1), 550-558, 2014
192014
Differential binding of latrunculins to G-actin: a molecular dynamics study
MA Helal, S Khalifa, S Ahmed
Journal of chemical information and modeling 53 (9), 2369-2375, 2013
192013
Deciphering the molecular basis of the kappa opioid receptor selectivity: A Molecular Dynamics study
AH Saleh, A Abdelwaly, KM Darwish, AAHM Eissa, A Chittiboyina, ...
Journal of Molecular Graphics and Modelling 106, 107940, 2021
172021
Homology modeling and explicit membrane molecular dynamics simulation to delineate the mode of binding of thiazolidinediones into FFAR1 and the mechanism of receptor activation
MA Helal, KM Darwish, MA Hammad
Bioorganic & Medicinal Chemistry Letters 24 (22), 5330-5336, 2014
172014
Anti-inflammatory effect of methoxyflavonoids from Chiliadenus montanus (Jasonia Montana) growing in Egypt
ES Habib, E El-Bsoumy, AK Ibrahim, MA Helal, MA El-Magd, SA Ahmed
Natural Product Research 35 (24), 5909-5913, 2021
162021
Molecular modeling and spectroscopic study of quinone–protein adducts: insight into toxicity, selectivity, and reversibility
MS Elgawish, N Kishikawa, MA Helal, K Ohyama, N Kuroda
Toxicology Research, 843-847, 2015
162015
Synthesis and biological evaluation of novel cYY analogues targeting Mycobacterium tuberculosis CYP121A1
SM Kishk, KJ McLean, S Sood, MA Helal, MS Gomaa, I Salama, ...
Bioorganic & Medicinal Chemistry 27 (8), 1546-1561, 2019
152019
Anticancer Effects of New Ceramides Isolated from the Red Sea Red Algae Hypnea musciformis in a Model of Ehrlich Ascites Carcinoma: LC-HRMS Analysis …
SS Elhady, ES Habib, RFA Abdelhameed, MS Goda, RM Hazem, ...
Marine Drugs 20 (1), 63, 2022
142022
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