Mohamed Helal
Mohamed Helal
Verified email at zewailcity.edu.eg
Title
Cited by
Cited by
Year
Design, synthesis, and biological evaluation of novel thiazolidinediones as PPARγ/FFAR1 dual agonists
KM Darwish, I Salama, S Mostafa, MS Gomaa, MA Helal
European journal of medicinal chemistry 109, 157-172, 2016
482016
Molecular basis of the potential interaction of SARS-CoV-2 spike protein to CD147 in COVID-19 associated-lymphopenia
MA Helal, S Shouman, A Abdelwaly, AO Elmehrath, M Essawy, SM Sayed, ...
Journal of Biomolecular Structure and Dynamics, 1-11, 2020
332020
Design, synthesis, and development of novel guaianolide-endoperoxides as potential antimalarial agents
L Sun, F Shah, MA Helal, Y Wu, Y Pedduri, AG Chittiboyina, J Gut, ...
Journal of medicinal chemistry 53 (21), 7864-7868, 2010
302010
Selective kappa opioid antagonists for treatment of addiction, are we there yet?
MA Helal, ES Habib, AG Chittiboyina
European journal of medicinal chemistry 141, 632-647, 2017
272017
VALIDATED RP-HPLC METHOD FOR SIMULTANEOUS DETERMINATION OF CANAGLIFLOZIN, DAPAGLIFLOZIN, EMPAGLIFLOZIN AND METFORMIN.
GA Khalil, I Salama, MS Gomaa, MA Helal
International Journal of Pharmaceutical, Chemical & Biological Sciences 8 (1), 2018
262018
Design, synthesis, and enzyme kinetics of novel benzimidazole and quinoxaline derivatives as methionine synthase inhibitors
H Elshihawy, MA Helal, M Said, MA Hammad
Bioorganic & medicinal chemistry 22 (1), 550-558, 2014
172014
Novel pyrazoles and pyrazolo [1, 2-a] pyridazines as selective COX-2 inhibitors; ultrasound-assisted synthesis, biological evaluation, and DFT calculations
N Ghareb, HA Elshihawy, MM Abdel-Daim, MA Helal
Bioorganic & medicinal chemistry letters 27 (11), 2377-2383, 2017
152017
Synthesis, biological evaluation, and molecular docking investigation of benzhydrol-and indole-based dual PPAR-γ/FFAR1 agonists
KM Darwish, I Salama, S Mostafa, MS Gomaa, ES Khafagy, MA Helal
Bioorganic & medicinal chemistry letters 28 (9), 1595-1602, 2018
142018
Homology modeling and explicit membrane molecular dynamics simulation to delineate the mode of binding of thiazolidinediones into FFAR1 and the mechanism of receptor activation
MA Helal, KM Darwish, MA Hammad
Bioorganic & medicinal chemistry letters 24 (22), 5330-5336, 2014
142014
Design and synthesis of imidazole and triazole pyrazoles as mycobacterium tuberculosis CYP121A1 inhibitors
SM Kishk, KJ McLean, S Sood, D Smith, JWD Evans, MA Helal, ...
ChemistryOpen 8 (7), 995, 2019
122019
Molecular modeling and spectroscopic study of quinone–protein adducts: insight into toxicity, selectivity, and reversibility
MS Elgawish, N Kishikawa, MA Helal, K Ohyama, N Kuroda
Toxicology Research, 843-847, 2015
122015
Combined receptor-based and ligand-based approach to delineate the mode of binding of guaianolide–endoperoxides to PfATP6
MA Helal, MA Avery
Bioorganic & medicinal chemistry letters 22 (17), 5410-5414, 2012
112012
Differential binding of latrunculins to G-actin: a molecular dynamics study
MA Helal, S Khalifa, S Ahmed
Journal of chemical information and modeling 53 (9), 2369-2375, 2013
102013
New insights into the binding mode of melanin concentrating hormone receptor-1 antagonists: Homology modeling and explicit membrane molecular dynamics simulation study
MA Helal, AG Chittiboyina, MA Avery
Journal of chemical information and modeling 51 (3), 635-646, 2011
102011
Development and validation of an HPLC-UV method for simultaneous determination of sildenafil and tramadol in biological fluids: Application to drug-drug interaction study
HE Dahshan, MA Helal, SM Mostafa, MS Elgawish
Journal of pharmaceutical and biomedical analysis 168, 201-208, 2019
92019
Cytotoxic activity evaluation and molecular docking study of phenolic derivatives from Achillea fragrantissima (Forssk.) growing in Egypt
BM Awad, ES Habib, AK Ibrahim, AS Wanas, MM Radwan, MA Helal, ...
Medicinal Chemistry Research 26 (9), 2065-2073, 2017
92017
Synthesis and biological evaluation of novel cYY analogues targeting Mycobacterium tuberculosis CYP121A1
SM Kishk, KJ McLean, S Sood, MA Helal, MS Gomaa, I Salama, ...
Bioorganic & medicinal chemistry 27 (8), 1546-1561, 2019
82019
Discovery of tetrahydro--carboline derivatives as a new class of phosphodiesterase 4 inhibitors
A Abdelwaly, I Salama, MS Gomaa, MA Helal
Medicinal Chemistry Research 26 (12), 3173-3187, 2017
72017
Interaction of nanoparticles with biological macromolecules: A review of molecular docking studies
AS Abdelsattar, A Dawoud, MA Helal
Nanotoxicology 15 (1), 66-95, 2021
42021
Deciphering the molecular basis of the kappa opioid receptor selectivity: A Molecular Dynamics study
AH Saleh, A Abdelwaly, KM Darwish, AAHM Eissa, A Chittiboyina, ...
Journal of Molecular Graphics and Modelling 106, 107940, 2021
22021
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