Jamie Vandenberg
Jamie Vandenberg
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hERG K+ channels: structure, function, and clinical significance
JI Vandenberg, MD Perry, MJ Perrin, SA Mann, Y Ke, AP Hill
Physiological reviews, 2012
Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a
GA Papadatos, PMR Wallerstein, CEG Head, R Ratcliff, PA Brady, ...
Proceedings of the National Academy of Sciences 99 (9), 6210-6215, 2002
HERG K+ channels: friend and foe
JI Vandenberg, BD Walker, TJ Campbell
Trends in Pharmacological Sciences 22 (5), 240-246, 2001
A new perspective in the field of cardiac safety testing through the comprehensive in vitro proarrhythmia assay paradigm
B Fermini, JC Hancox, N Abi-Gerges, M Bridgland-Taylor, KW Chaudhary, ...
Journal of biomolecular screening 21 (1), 1-11, 2016
Mechanisms of pHi recovery after global ischemia in the perfused heart.
JI Vandenberg, JC Metcalfe, AA Grace
Circulation research 72 (5), 993-1003, 1993
Stretch-Sensitive KCNQ1Mutation: A Link Between Genetic and Environmental Factors in the Pathogenesis of Atrial Fibrillation?
R Otway, JI Vandenberg, G Guo, A Varghese, ML Castro, J Liu, JT Zhao, ...
Journal of the American College of Cardiology 49 (5), 578-586, 2007
Domain reorientation and rotation of an intracellular assembly regulate conduction in Kir potassium channels
OB Clarke, AT Caputo, AP Hill, JI Vandenberg, BJ Smith, JM Gulbis
Cell 141 (6), 1018-1029, 2010
Swelling-activated and isoprenaline-activated chloride currents in guinea pig cardiac myocytes have distinct electrophysiology and pharmacology.
JI Vandenberg, A Yoshida, K Kirk, T Powell
The Journal of general physiology 104 (6), 997-1017, 1994
The sodium channel β-subunit SCN3b modulates the kinetics of SCN5a and is expressed heterogeneously in sheep heart
AI Fahmi, M Patel, EB Stevens, AL Fowden, JE John III, K Lee, R Pinnock, ...
The Journal of physiology 537 (Pt 3), 693, 2001
Cell swelling and ion transport pathways in cardiac myocytes
JI Vandenberg, SA Rees, AR Wright, T Powell
Cardiovascular research 32 (1), 85-97, 1996
Sinus node dysfunction following targeted disruption of the murine cardiac sodium channel gene Scn5a
M Lei, C Goddard, J Liu, AL Léoni, A Royer, SSM Fung, G Xiao, A Ma, ...
The Journal of physiology 567 (2), 387-400, 2005
Drug binding to the inactivated state is necessary but not sufficient for high-affinity binding to human ether-a-go-go-related gene channels
MJ Perrin, PW Kuchel, TJ Campbell, JI Vandenberg
Molecular Pharmacology 74 (5), 1443-1452, 2008
Human ether-a-go-go related gene (hERG) K+ channels: function and dysfunction
MJ Perrin, RN Subbiah, JI Vandenberg, AP Hill
Progress in biophysics and molecular biology 98 (2-3), 137-148, 2008
Effects of premature stimulation on HERG K+ channels
YL Martyn, P Mahaut‐Smith, A Varghese, CLH Huang, PR Kemp, ...
The Journal of physiology 537 (3), 843-851, 2001
R222Q SCN5A Mutation Is Associated With Reversible Ventricular Ectopy and Dilated Cardiomyopathy
SA Mann, ML Castro, M Ohanian, G Guo, P Zodgekar, A Sheu, ...
Journal of the American College of Cardiology 60 (16), 1566-1573, 2012
Temperature dependence of human ether-à-go-go-related gene K+ currents
JI Vandenberg, A Varghese, Y Lu, JA Bursill, MP Mahaut-Smith, ...
American Journal of Physiology-Cell Physiology 291 (1), C165-C175, 2006
A universal and robust integrated platform for the scalable production of human cardiomyocytes from pluripotent stem cells
H Fonoudi, H Ansari, S Abbasalizadeh, MR Larijani, S Kiani, ...
Stem cells translational medicine 4 (12), 1482-1494, 2015
Lentiviral vectors for delivery of genes into neonatal and adult ventricular cardiac myocytes in vitro and in vivo
J Zhao, GJ Pettigrew, J Thomas, JI Vandenberg, L Delriviere, EM Bolton, ...
Basic research in cardiology 97, 348-358, 2002
Potassium channels in the heart: structure, function and regulation
E Grandi, MC Sanguinetti, DC Bartos, DM Bers, Y Chen‐Izu, ...
The Journal of physiology 595 (7), 2209-2228, 2017
The N–terminal tail of hERG contains an amphipathic α–helix that regulates channel deactivation
CA Ng, MJ Hunter, MD Perry, M Mobli, Y Ke, PW Kuchel, GF King, D Stock, ...
PloS one 6 (1), e16191, 2011
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