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Steven D Cappell
Steven D Cappell
National Cancer Institute
Verified email at nih.gov - Homepage
Title
Cited by
Cited by
Year
The proliferation-quiescence decision is controlled by a bifurcation in CDK2 activity at mitotic exit
SL Spencer, SD Cappell, FC Tsai, KW Overton, CL Wang, T Meyer
Cell 155 (2), 369-383, 2013
6862013
Irreversible APCCdh1 inactivation underlies the point of no return for cell-cycle entry
SD Cappell, M Chung, A Jaimovich, SL Spencer, T Meyer
Cell 166 (1), 167-180, 2016
2482016
EMI1 switches from being a substrate to an inhibitor of APC/CCDH1 to start the cell cycle
SD Cappell, KG Mark, D Garbett, LR Pack, M Rape, T Meyer
Nature 558 (7709), 313-317, 2018
1352018
Regulators of G-protein signaling accelerate GPCR signaling kinetics and govern sensitivity solely by accelerating GTPase activity
NA Lambert, CA Johnston, SD Cappell, S Kuravi, AJ Kimple, FS Willard, ...
Proceedings of the National Academy of Sciences 107 (15), 7066-7071, 2010
1052010
Selective role for RGS12 as a Ras/Raf/MEK scaffold in nerve growth factor‐mediated differentiation
MD Willard, FS Willard, X Li, SD Cappell, WD Snider, DP Siderovski
The EMBO journal 26 (8), 2029-2040, 2007
972007
Transient hysteresis in CDK4/6 activity underlies passage of the restriction point in G1
M Chung, C Liu, HW Yang, MS Köberlin, SD Cappell, T Meyer
Molecular cell 76 (4), 562-573. e4, 2019
922019
Stress-mediated exit to quiescence restricted by increasing persistence in CDK4/6 activation
HW Yang, SD Cappell, A Jaimovich, C Liu, M Chung, LH Daigh, LR Pack, ...
Elife 9, e44571, 2020
682020
Systematic analysis of essential genes reveals important regulators of G protein signaling
SD Cappell, R Baker, D Skowyra, HG Dohlman
Molecular cell 38 (5), 746-757, 2010
452010
Loss of CDK4/6 activity in S/G2 phase leads to cell cycle reversal
JA Cornwell, A Crncec, MM Afifi, K Tang, R Amin, SD Cappell
Nature 619 (7969), 363-370, 2023
362023
Nuclear pore protein NUP210 depletion suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response
R Amin, A Shukla, JJ Zhu, S Kim, P Wang, SZ Tian, AD Tran, D Paul, ...
Nature Communications 12 (1), 7216, 2021
342021
Cell cycle-dependent phosphorylation and ubiquitination of a G protein α subunit
MP Torres, ST Clement, SD Cappell, HG Dohlman
Journal of Biological Chemistry 286 (23), 20208-20216, 2011
332011
Cell cycle inertia underlies a bifurcation in cell fates after DNA damage
JF Nathans, JA Cornwell, MM Afifi, D Paul, SD Cappell
Science advances 7 (3), eabe3882, 2021
252021
Selective regulation of MAP kinase signaling by an endomembrane phosphatidylinositol 4-kinase
SD Cappell, HG Dohlman
Journal of Biological Chemistry 286 (17), 14852-14860, 2011
252011
Apoptosis-induced nuclear expulsion in tumor cells drives S100a4-mediated metastatic outgrowth through the RAGE pathway
WY Park, JM Gray, RJ Holewinski, T Andresson, JY So, ...
Nature Cancer 4 (3), 419-435, 2023
242023
The RepID–CRL4 ubiquitin ligase complex regulates metaphase to anaphase transition via BUB3 degradation
SM Jang, JF Nathans, H Fu, CE Redon, LM Jenkins, BL Thakur, ...
Nature Communications 11 (1), 24, 2020
242020
Estrogen and progesterone lower cyclin B1 AND D1 expression, block cell cycle in G2/M, and trigger apoptosis in human adrenal carcinoma cell cultures
JW Brown, LM Prieto, C Perez-Stable, M Montoya, S Cappell, ...
Hormone and metabolic research 40 (05), 306-310, 2008
222008
Ribosome biogenesis is a downstream effector of the oncogenic U2AF1-S34F mutation
A Akef, K McGraw, SD Cappell, DR Larson
PLoS biology 18 (11), e3000920, 2020
212020
Revealing β-TrCP activity dynamics in live cells with a genetically encoded biosensor
D Paul, SC Kales, JA Cornwell, MM Afifi, G Rai, A Zakharov, A Simeonov, ...
Nature Communications 13 (1), 6364, 2022
142022
Extracts from two marine sponges lower cyclin B1 levels, cause a G2/M cell cycle block and trigger apoptosis in SW-13 human adrenal carcinoma cells
JW Brown, S Cappell, C Perez-Stable, LM Fishman
Toxicon 43 (7), 841-846, 2004
112004
Irreversible cell cycle exit associated with senescence is mediated by constitutive MYC degradation
MM Afifi, A Crncec, JA Cornwell, C Cataisson, D Paul, LM Ghorab, ...
Cell reports 42 (9), 2023
92023
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