Construction and analysis of two genome-scale deletion libraries for Bacillus subtilis BM Koo, G Kritikos, JD Farelli, H Todor, K Tong, H Kimsey, I Wapinski, ... Cell systems 4 (3), 291-305. e7, 2017 | 549 | 2017 |
Enzyme promiscuity: engine of evolutionary innovation C Pandya, JD Farelli, D Dunaway-Mariano, KN Allen Journal of Biological Chemistry 289 (44), 30229-30236, 2014 | 160 | 2014 |
Panoramic view of a superfamily of phosphatases through substrate profiling H Huang, C Pandya, C Liu, NF Al-Obaidi, M Wang, L Zheng, ... Proceedings of the National Academy of Sciences 112 (16), E1974-E1983, 2015 | 159 | 2015 |
Optimization of mRNA untranslated regions for improved expression of therapeutic mRNA KH Asrani, JD Farelli, MR Stahley, RL Miller, CJ Cheng, RR Subramanian, ... RNA biology 15 (6), 756-762, 2018 | 111 | 2018 |
G6PC mRNA therapy positively regulates fasting blood glucose and decreases liver abnormalities in a mouse model of glycogen storage disease 1a DS Roseman, T Khan, F Rajas, LS Jun, KH Asrani, C Isaacs, JD Farelli, ... Molecular Therapy 26 (3), 814-821, 2018 | 70 | 2018 |
Divergence of Structure and Function in the Haloacid Dehalogenase Enzyme Superfamily: Bacteroides thetaiotaomicron BT2127 Is an Inorganic Pyrophosphatase H Huang, Y Patskovsky, R Toro, JD Farelli, C Pandya, SC Almo, KN Allen, ... Biochemistry 50 (41), 8937-8949, 2011 | 47 | 2011 |
Structure of the Trehalose-6-phosphate Phosphatase from Brugia malayi Reveals Key Design Principles for Anthelmintic Drugs JD Farelli, BD Galvin, Z Li, C Liu, M Aono, M Garland, OE Hallett, ... PLoS pathogens 10 (7), e1004245, 2014 | 45 | 2014 |
Covalent docking predicts substrates for haloalkanoate dehalogenase superfamily phosphatases N London, JD Farelli, SD Brown, C Liu, H Huang, M Korczynska, ... Biochemistry 54 (2), 528-537, 2015 | 31 | 2015 |
Substrate deconstruction and the nonadditivity of enzyme recognition S Barelier, JA Cummings, AM Rauwerdink, DS Hitchcock, JD Farelli, ... Journal of the American Chemical Society 136 (20), 7374-7382, 2014 | 25 | 2014 |
Structure and function of interacting IcmR-IcmQ domains from a type IVb secretion system in Legionella pneumophila S Raychaudhury, JD Farelli, TP Montminy, M Matthews, JF Ménétret, ... Structure 17 (4), 590-601, 2009 | 24 | 2009 |
Human brown fat inducible thioesterase variant 2 cellular localization and catalytic function D Chen, J Latham, H Zhao, M Bisoffi, J Farelli, D Dunaway-Mariano Biochemistry 51 (35), 6990-6999, 2012 | 23 | 2012 |
Structure and Catalysis in the Escherichia coli Hotdog-fold Thioesterase Paralogs YdiI and YbdB R Wu, JA Latham, D Chen, J Farelli, H Zhao, K Matthews, KN Allen, ... Biochemistry 53 (29), 4788-4805, 2014 | 17 | 2014 |
Construction and Analysis of Two Genome-Scale Deletion Libraries for Bacillus subtilis. Cell Syst. 2017; 4 (3): 291–305 e7 BM Koo, G Kritikos, JD Farelli, H Todor, K Tong, H Kimsey, I Wapinski, ... Epub 2017/02/13. https://doi. org/10.1016/j. cels. 2016.12. 013 PMID: 28189581, 0 | 14 | |
Construction and analysis of two genome-scale deletion libraries for Bacillus subtilis. Cell Syst. 2017; 4: 291–305. e7 BM Koo, G Kritikos, JD Farelli, H Todor, K Tong, H Kimsey, I Wapinski, ... | 12 | |
Leveraging rational protein engineering to improve mRNA therapeutics JD Farelli, KH Asrani, C Isaacs, JS deBear, MR Stahley, A Shah, ... nucleic acid therapeutics 28 (2), 74-85, 2018 | 10 | 2018 |
IcmQ in the Type 4b secretion system contains an NAD+ binding domain JD Farelli, JC Gumbart, IV Akey, A Hempstead, W Amyot, JF Head, ... Structure 21 (8), 1361-1373, 2013 | 9 | 2013 |
Dissociation between serotonin neurotoxicity and brain-derived neurotrophic factor induction following neonatal MDMA exposure in rats BJ Piper, JD Farelli, JS Meyer Developmental Neuroscience 31 (1-2), 90-94, 2009 | 7 | 2009 |
On the unyielding hydrophobic core of villin headpiece JW Brown, JD Farelli, CJ McKnight Protein Science 21 (5), 647-654, 2012 | 6 | 2012 |
On unsatisfied hydrogen bonds in the N-terminal subdomain of villin headpiece JW Brown, JD Farelli, CJ McKnight Journal of molecular biology 413 (3), 543-547, 2011 | 6 | 2011 |
811 Peters JM, Hachmann AB, Rudner DZ, Allen KN, Typas A, Gross CA. 2017 BM Koo, G Kritikos, JD Farelli, H Todor, K Tong, H Kimsey, I Wapinski, ... Construction and 812, 291-305, 0 | 6 | |