Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas M Sanson, Y Marie, S Paris, A Idbaih, J Laffaire, F Ducray, S El Hallani, ... J Clin Oncol 27 (25), 4150-4154, 2009 | 1175 | 2009 |
IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas C Houillier, X Wang, G Kaloshi, K Mokhtari, R Guillevin, J Laffaire, S Paris, ... Neurology 75 (17), 1560-1566, 2010 | 583 | 2010 |
Ectopic activation of germline and placental genes identifies aggressive metastasis-prone lung cancers S Rousseaux, A Debernardi, B Jacquiau, AL Vitte, A Vesin, ... Science translational medicine 5 (186), 186ra66-186ra66, 2013 | 465 | 2013 |
All the 1p19q codeleted gliomas are mutated on IDH1 or IDH2 M Labussiere, A Idbaih, XW Wang, Y Marie, B Boisselier, C Falet, S Paris, ... Neurology 74 (23), 1886-1890, 2010 | 319 | 2010 |
Methylation profiling identifies 2 groups of gliomas according to their tumorigenesis J Laffaire, S Everhard, A Idbaih, E Criniere, Y Marie, A de Reynies, ... Neuro-oncology 13 (1), 84-98, 2010 | 159 | 2010 |
Polytherapy with a combination of three repurposed drugs (PXT3003) down-regulates Pmp22 over-expression and improves myelination, axonal and functional … I Chumakov, A Milet, N Cholet, G Primas, A Boucard, Y Pereira, ... Orphanet journal of rare diseases 9, 1-16, 2014 | 105 | 2014 |
Genomic aberrations in lung adenocarcinoma in never smokers B Job, A Bernheim, M Beau-Faller, S Camilleri-Broët, P Girard, P Hofman, ... PloS one 5 (12), e15145, 2010 | 79 | 2010 |
A Comparative and Integrative Approach Identifies ATPase Family, AAA Domain Containing 2 as a Likely Driver of Cell Proliferation in Lung Adenocarcinoma R Fouret, J Laffaire, P Hofman, M Beau-Faller, J Mazieres, P Validire, ... Clinical cancer Research 18 (20), 5606-5616, 2012 | 75 | 2012 |
Transcriptional disruptions in Down syndrome: a case study in the Ts1Cje mouse cerebellum during post‐natal development MC Potier, I Rivals, G Mercier, L Ettwiller, RX Moldrich, J Laffaire, ... Journal of neurochemistry 97, 104-109, 2006 | 68 | 2006 |
Down syndrome gene dosage imbalance on cerebellum development RX Moldrich, L Dauphinot, J Laffaire, J Rossier, MC Potier Progress in neurobiology 82 (2), 87-94, 2007 | 65 | 2007 |
Gene expression signature of cerebellar hypoplasia in a mouse model of Down syndrome during postnatal development J Laffaire, I Rivals, L Dauphinot, F Pasteau, R Wehrle, B Larrat, T Vitalis, ... Bmc Genomics 10, 1-15, 2009 | 64 | 2009 |
Lung squamous cell carcinomas with basaloid histology represent a specific molecular entity C Brambilla, J Laffaire, S Lantuejoul, D Moro-Sibilot, H Mignotte, F Arbib, ... Clinical cancer research 20 (22), 5777-5786, 2014 | 58 | 2014 |
A novel TMEM127 mutation in a patient with familial bilateral pheochromocytoma N Burnichon, C Lepoutre-Lussey, J Laffaire, N Gadessaud, V Molinié, ... European Journal of Endocrinology 164 (1), 141-145, 2011 | 57 | 2011 |
Proliferation deficits and gene expression dysregulation in Down's syndrome (Ts1Cje) neural progenitor cells cultured from neurospheres RX Moldrich, L Dauphinot, J Laffaire, T Vitalis, Y Hérault, PM Beart, ... Journal of neuroscience research 87 (14), 3143-3152, 2009 | 56 | 2009 |
Increased NR2A expression and prolonged decay of NMDA-induced calcium transient in cerebellum of TgDyrk1A mice, a mouse model of Down syndrome X Altafaj, J Ortiz-Abalia, M Fernandez, MC Potier, J Laffaire, N Andreu, ... Neurobiology of Disease 32 (3), 377-384, 2008 | 38 | 2008 |
Combination of acamprosate and baclofen as a promising therapeutic approach for Parkinson’s disease R Hajj, A Milet, D Toulorge, N Cholet, J Laffaire, J Foucquier, S Robelet, ... Scientific Reports 5 (1), 16084, 2015 | 36 | 2015 |
Chromosome 9p and 10q losses predict unfavorable outcome in low-grade gliomas C Houillier, K Mokhtari, C Carpentier, E Criniere, Y Marie, A Rousseau, ... Neuro-oncology 12 (1), 2-6, 2010 | 33 | 2010 |
Transmembrane protein 50b (C21orf4), a candidate for Down syndrome neurophenotypes, encodes an intracellular membrane protein expressed in the rodent brain RX Moldrich, J Laine, A Visel, PM Beart, J Laffaire, J Rossier, MC Potier Neuroscience 154 (4), 1255-1266, 2008 | 21 | 2008 |
Synergistic PXT3003 therapy uncouples neuromuscular function from dysmyelination in male Charcot–Marie–Tooth disease type 1A (CMT1A) rats T Prukop, S Wernick, L Boussicault, D Ewers, K Jäger, J Adam, L Winter, ... Journal of neuroscience research 98 (10), 1933-1952, 2020 | 19 | 2020 |
Combination of acamprosate and baclofen (PXT864) as a potential new therapy for amyotrophic lateral sclerosis L Boussicault, J Laffaire, P Schmitt, P Rinaudo, N Callizot, S Nabirotchkin, ... Journal of neuroscience research 98 (12), 2435-2450, 2020 | 16 | 2020 |