متابعة
John F. Engelhardt, Ph.D.
John F. Engelhardt, Ph.D.
Professor and Chair, Department of Anatomy and Cell Biology
بريد إلكتروني تم التحقق منه على uiowa.edu
عنوان
عدد مرات الاقتباسات
عدد مرات الاقتباسات
السنة
A revised airway epithelial hierarchy includes CFTR-expressing ionocytes
DT Montoro, AL Haber, M Biton, V Vinarsky, B Lin, SE Birket, F Yuan, ...
Nature 560 (7718), 319-324, 2018
10802018
Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver.
JF Engelhardt, X Ye, B Doranz, JM Wilson
Proceedings of the National Academy of Sciences 91 (13), 6196-6200, 1994
8281994
Submucosal glands are the predominant site of CFTR expression in the human bronchus
JF Engelhardt, JR Yankaskas, SA Ernst, Y Yang, CR Marino, RC Boucher, ...
Nature genetics 2 (3), 240-248, 1992
8131992
Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia
M Grossman, SE Raper, K Kozarsky, EA Stein, JF Engelhardt, D Muller, ...
Nature genetics 6 (4), 335-341, 1994
7371994
A controlled study of adenoviral-vector–mediated gene transfer in the nasal epithelium of patients with cystic fibrosis
MR Knowles, KW Hohneker, Z Zhou, JC Olsen, TL Noah, PC Hu, ...
New England Journal of Medicine 333 (13), 823-831, 1995
7151995
Modular flexibility of dystrophin: implications for gene therapy of Duchenne muscular dystrophy
SQ Harper, MA Hauser, C DelloRusso, D Duan, RW Crawford, SF Phelps, ...
Nature medicine 8 (3), 253-261, 2002
6782002
Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue
D Duan, P Sharma, J Yang, Y Yue, L Dudus, Y Zhang, KJ Fisher, ...
Journal of virology 72 (11), 8568-8577, 1998
6481998
Inactivation of E2a in recombinant adenoviruses improves the prospect for gene therapy in cystic fibrosis
Y Yang, FA Nunes, K Berencsi, E Gönczöl, JF Engelhardt, JM Wilson
Nature genetics 7 (3), 362-369, 1994
5961994
Production of CFTR-null and CFTR-ΔF508 heterozygous pigs by adeno-associated virus–mediated gene targeting and somatic cell nuclear transfer
CS Rogers, Y Hao, T Rokhlina, M Samuel, DA Stoltz, Y Li, E Petroff, ...
The Journal of clinical investigation 118 (4), 1571-1577, 2008
5052008
Targeted injury of type II alveolar epithelial cells induces pulmonary fibrosis
TH Sisson, M Mendez, K Choi, N Subbotina, A Courey, A Cunningham, ...
American journal of respiratory and critical care medicine 181 (3), 254-263, 2010
5012010
Airway epithelial cells: current concepts and challenges
RG Crystal, SH Randell, JF Engelhardt, J Voynow, ME Sunday
Proceedings of the American Thoracic Society 5 (7), 772-777, 2008
4972008
Lipopolysaccharide induces Rac1-dependent reactive oxygen species formation and coordinates tumor necrosis factor-α secretion through IKK regulation of NF-κB
S Sanlioglu, CM Williams, L Samavati, NS Butler, G Wang, PB McCray, ...
Journal of Biological Chemistry 276 (32), 30188-30198, 2001
4962001
Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus
D Duan, Y Yue, Z Yan, J Yang, JF Engelhardt
The Journal of clinical investigation 105 (11), 1573-1587, 2000
4812000
CD4 (+) T-lymphocytes mediate ischemia/reperfusion-induced inflammatory responses in mouse liver.
RM Zwacka, Y Zhang, J Halldorson, H Schlossberg, L Dudus, ...
The Journal of clinical investigation 100 (2), 279-289, 1997
4501997
SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model
MM Harraz, JJ Marden, W Zhou, Y Zhang, A Williams, VS Sharov, ...
The Journal of clinical investigation 118 (2), 659-670, 2008
4282008
Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis
X Sun, H Sui, JT Fisher, Z Yan, X Liu, HJ Cho, NS Joo, Y Zhang, W Zhou, ...
The Journal of clinical investigation 120 (9), 3149-3160, 2010
4112010
Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: toxicity study
RH Simon, JF Engelhardt, Y Yang, M Zepeda, S Weber-Pendleton, ...
Human Gene Therapy 4 (6), 771-780, 1993
4091993
Endocytosis and nuclear trafficking of adeno-associated virus type 2 are controlled by rac1 and phosphatidylinositol-3 kinase activation
S Sanlioglu, PK Benson, J Yang, EM Atkinson, T Reynolds, JF Engelhardt
Journal of virology 74 (19), 9184-9196, 2000
4072000
Inefficient gene transfer by adenovirus vector to cystic fibrosis airway epithelia of mice and humans
BR Grubb, RJ Pickles, H Ye, JR Yankaskas, RN Vick, JF Engelhardt, ...
Nature 371 (6500), 802-806, 1994
4061994
Direct gene transfer of human CFTR into human bronchial epithelia of xenografts with E1–deleted adenoviruses
JF Engelhardt, Y Yang, LD Stratford-Perricaudet, ED Allen, K Kozarsky, ...
Nature Genetics 4 (1), 27-34, 1993
3921993
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مقالات 1–20