| Histone deacetylase inhibition decreases cholesterol levels in neuronal cells by modulating key genes in cholesterol synthesis, uptake and efflux MJ Nunes, M Moutinho, MJ Gama, CMP Rodrigues, E Rodrigues PloS one 8 (1), e53394, 2013 | 65 | 2013 |
| Sp proteins play a critical role in histone deacetylase inhibitor‐mediated derepression of CYP46A1 gene transcription MJ Nunes, I Milagre, M Schnekenburger, MJ Gama, M Diederich, ... Journal of neurochemistry 113 (2), 418-431, 2010 | 50 | 2010 |
| Transcriptional regulation of the human CYP46A1 brain‐specific expression by Sp transcription factors I Milagre, MJ Nunes, MJ Gama, RF Silva, JM Pascussi, MC Lechner, ... Journal of neurochemistry 106 (2), 835-849, 2008 | 49 | 2008 |
| Neuronal differentiation alters the ratio of Sp transcription factors recruited to the CYP46A1 promoter I Milagre, MJ Nunes, M Castro‐Caldas, M Moutinho, MJ Gama, ... Journal of neurochemistry, 2012 | 21 | 2012 |
| Demethylation of the Coding Region Triggers the Activation of the Human Testis-Specific PDHA2 Gene in Somatic Tissues A Pinheiro, MJ Nunes, I Milagre, E Rodrigues, MJ Silva, IT de Almeida, ... PloS one 7 (6), e38076, 2012 | 20 | 2012 |
| Chromatin-modifying agents increase transcription of CYP46A1, a key player in brain cholesterol elimination I Milagre, MJ Nunes, M Moutinho, I Rivera, A Fuso, S Scarpa, MJ Gama, ... Journal of Alzheimer's Disease 22 (4), 1209-1221, 2010 | 19 | 2010 |
| Marked change in the balance between CYP27A1 and CYP46A1 mediated elimination of cholesterol during differentiation of human neuronal cells I Milagre, M Olin, MJ Nunes, M Moutinho, A Lövgren-Sandblom, MJ Gama, ... Neurochemistry international, 2011 | 17 | 2011 |
| Okadaic acid inhibits the trichostatin A-mediated increase of human CYP46A1 neuronal expression in a ERK1/2-Sp3-dependent pathway MJ Nunes, M Moutinho, I Milagre, MJ Gama, E Rodrigues Journal of Lipid Research 53 (9), 1910-1919, 2012 | 13 | 2012 |
| Transcriptional regulatory mechanisms involved in CYP46A1 up-regulation by histone deacetylase inhibitors: from chromatin structure to transcription factors MJ Nunes | | 2012 |
| P3‐257: Derepression of the CYP46A1 gene transcription by histone deacetylase inhibition E Rodrigues, MJ Nunes, I Milagre, MJ Gama Alzheimer's & Dementia 4, T597-T597, 2008 | | 2008 |
| P3‐242: Role of Sp proteins in the transcriptional regulation of the brain‐specific CYP46A1 gene I Milagre, MJ Nunes, MJ Gama, RF Silva, JM Pascussi, MC Lechner, ... Alzheimer's & Dementia 4, T591-T592, 2008 | | 2008 |
Miguel MoutinhoStark Neurosciences Research InstituteVerified email at iu.edu
