Design and synthesis of methoxyphenyl-and coumarin-based chalcone derivatives as anti-inflammatory agents by inhibition of NO production and down-regulation of NF-κB in LPS … SH Emam, A Sonousi, EO Osman, D Hwang, GD Kim, RA Hassan Bioorganic Chemistry 107, 104630, 2021 | 64 | 2021 |
Apralogs: Apramycin 5-O-Glycosides and Ethers with Improved Antibacterial Activity and Ribosomal Selectivity and Reduced Susceptibility to the … JCK Quirke, P Rajasekaran, VA Sarpe, A Sonousi, I Osinnii, M Gysin, ... Journal of the American Chemical Society 142 (1), 530-544, 2019 | 28 | 2019 |
Effects of the 1-N-(4-Amino-2S-hydroxybutyryl) and 6′-N-(2-Hydroxyethyl) Substituents on Ribosomal Selectivity, Cochleotoxicity, and Antibacterial Activity in the … A Sonousi, VA Sarpe, M Brilkova, J Schacht, A Vasella, EC Böttger, ... ACS infectious diseases 4 (7), 1114-1120, 2018 | 26 | 2018 |
Design, synthesis and evaluation of anticancer activity of new pyrazoline derivatives by down-regulation of VEGF: Molecular docking and apoptosis inducing activity RA Hassan, SH Emam, D Hwang, GD Kim, SO Hassanin, MG Khalil, ... Bioorganic chemistry 118, 105487, 2022 | 23 | 2022 |
Design, synthesis and antiproliferative evaluation of new tricyclic fused thiazolopyrimidines targeting topoisomerase II: Molecular docking and apoptosis inducing activity MTM Nemr, A Sonousi, AA Marzouk Bioorganic Chemistry 105, 104446, 2020 | 20 | 2020 |
An Advanced Apralog with Increased in vitro and in vivo Activity toward Gram‐negative Pathogens and Reduced ex vivo Cochleotoxicity A Sonousi, JCK Quirke, P Waduge, T Janusic, M Gysin, K Haldimann, ... ChemMedChem 16 (2), 335-339, 2021 | 19 | 2021 |
Design, synthesis and in vitro PDE4 inhibition activity of certain quinazolinone derivatives for treatment of asthma AK Elansary, HH Kadry, EM Ahmed, ASM Sonousi Medicinal Chemistry Research 21, 3327-3335, 2012 | 19 | 2012 |
Antimicrobial activity of Vitex agnus-castus Essential Oil and Molecular Docking Study of Its Major Constituents RO Bakr, SS Zaghloul, RA Hassan, A Sonousi, R Wasfi, MAA Fayed Journal of Essential Oil Bearing Plants 23 (1), 184-193, 2020 | 18 | 2020 |
Design, synthesis, and biological activity of certain quinazolinedione derivatives as potent phosphodiestrase4 inhibitors AK Elansary, HH Kadry, EM Ahmed, ASM Sonousi Medicinal Chemistry Research 21, 3557-3567, 2012 | 13 | 2012 |
Novel adenosine derivatives against SARS-CoV-2 RNA-dependent RNA polymerase: an in silico perspective A Sonousi, HA Mahran, IM Ibrahim, MN Ibrahim, AA Elfiky, WM Elshemey Pharmacological Reports 73 (6), 1754-1764, 2021 | 12 | 2021 |
Synthesis of a pseudodisaccharide suitable for synthesis of ring I modified 4, 5-2-deoxystreptamine type aminoglycoside antibiotics A Sonousi, A Vasella, D Crich The Journal of organic chemistry 85 (11), 7583-7587, 2020 | 11 | 2020 |
Structure‐Activity Relationships for 5′′ Modifications of 4, 5‐Aminoglycoside Antibiotics JCK Quirke, GC Sati, A Sonousi, M Gysin, K Haldimann, EC Böttger, ... ChemMedChem 17 (13), e202200120, 2022 | 10 | 2022 |
Selective Protection of Secondary Amines as the N-Phenyltriazenes. Application to Aminoglycoside Antibiotics A Sonousi, D Crich Organic letters 17 (16), 4006-4009, 2015 | 10 | 2015 |
Design and synthesis of novel quinazolinone-based derivatives as EGFR inhibitors with antitumor activity A Sonousi, RA Hassan, EO Osman, AM Abdou, SH Emam Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 2644-2659, 2022 | 8 | 2022 |
New trends in synthetic drugs and natural products targeting 20S proteasomes in cancers H Atta, N Alzahaby, NM Hamdy, SH Emam, A Sonousi, L Ziko Bioorganic chemistry 133, 106427, 2023 | 7 | 2023 |
Design, synthesis, anticancer, and antibacterial evaluation of some quinazolinone‐based derivatives as DHFR inhibitors EO Osman, SH Emam, A Sonousi, MM Kandil, AM Abdou, RA Hassan Drug Development Research 84 (5), 888-906, 2023 | 6 | 2023 |
Synthesis, ribosomal selectivity, and antibacterial activity of netilmicin 4′-derivatives A Sonousi, D Shcherbakov, A Vasella, EC Böttger, D Crich MedChemComm 10 (6), 946-950, 2019 | 3 | 2019 |
Synthesis Of Netilmicin And Apramycin Derivatives For The Treatment Of Multidrug-Resistant Infectious Diseases ASM Sonousi | 2 | 2017 |
Design, synthesis, and biological evaluation of 1, 2, 4-oxadiazole-based derivatives as multitarget anti-Alzheimer agents MS Ayoup, MR Barakat, H Abdel-Hamid, E Emam, YS Al-Faiyz, ... RSC Medicinal Chemistry, 2024 | | 2024 |
Novel sulfonamide derivatives as multitarget antidiabetic agents: design, synthesis, and biological evaluation MS Ayoup, N Khaled, H Abdel-Hamid, DA Ghareeb, SA Nasr, A Omer, ... RSC advances 14 (11), 7664-7675, 2024 | | 2024 |