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Amr Sonousi
Amr Sonousi
Assistant Professor of Pharmaceutical Organic Chemistry, Cairo University
Verified email at pharma.cu.edu.eg
Title
Cited by
Cited by
Year
Design and synthesis of methoxyphenyl-and coumarin-based chalcone derivatives as anti-inflammatory agents by inhibition of NO production and down-regulation of NF-κB in LPS …
SH Emam, A Sonousi, EO Osman, D Hwang, GD Kim, RA Hassan
Bioorganic Chemistry 107, 104630, 2021
642021
Apralogs: Apramycin 5-O-Glycosides and Ethers with Improved Antibacterial Activity and Ribosomal Selectivity and Reduced Susceptibility to the …
JCK Quirke, P Rajasekaran, VA Sarpe, A Sonousi, I Osinnii, M Gysin, ...
Journal of the American Chemical Society 142 (1), 530-544, 2019
282019
Effects of the 1-N-(4-Amino-2S-hydroxybutyryl) and 6′-N-(2-Hydroxyethyl) Substituents on Ribosomal Selectivity, Cochleotoxicity, and Antibacterial Activity in the …
A Sonousi, VA Sarpe, M Brilkova, J Schacht, A Vasella, EC Böttger, ...
ACS infectious diseases 4 (7), 1114-1120, 2018
262018
Design, synthesis and evaluation of anticancer activity of new pyrazoline derivatives by down-regulation of VEGF: Molecular docking and apoptosis inducing activity
RA Hassan, SH Emam, D Hwang, GD Kim, SO Hassanin, MG Khalil, ...
Bioorganic chemistry 118, 105487, 2022
232022
Design, synthesis and antiproliferative evaluation of new tricyclic fused thiazolopyrimidines targeting topoisomerase II: Molecular docking and apoptosis inducing activity
MTM Nemr, A Sonousi, AA Marzouk
Bioorganic Chemistry 105, 104446, 2020
202020
An Advanced Apralog with Increased in vitro and in vivo Activity toward Gram‐negative Pathogens and Reduced ex vivo Cochleotoxicity
A Sonousi, JCK Quirke, P Waduge, T Janusic, M Gysin, K Haldimann, ...
ChemMedChem 16 (2), 335-339, 2021
192021
Design, synthesis and in vitro PDE4 inhibition activity of certain quinazolinone derivatives for treatment of asthma
AK Elansary, HH Kadry, EM Ahmed, ASM Sonousi
Medicinal Chemistry Research 21, 3327-3335, 2012
192012
Antimicrobial activity of Vitex agnus-castus Essential Oil and Molecular Docking Study of Its Major Constituents
RO Bakr, SS Zaghloul, RA Hassan, A Sonousi, R Wasfi, MAA Fayed
Journal of Essential Oil Bearing Plants 23 (1), 184-193, 2020
182020
Design, synthesis, and biological activity of certain quinazolinedione derivatives as potent phosphodiestrase4 inhibitors
AK Elansary, HH Kadry, EM Ahmed, ASM Sonousi
Medicinal Chemistry Research 21, 3557-3567, 2012
132012
Novel adenosine derivatives against SARS-CoV-2 RNA-dependent RNA polymerase: an in silico perspective
A Sonousi, HA Mahran, IM Ibrahim, MN Ibrahim, AA Elfiky, WM Elshemey
Pharmacological Reports 73 (6), 1754-1764, 2021
122021
Synthesis of a pseudodisaccharide suitable for synthesis of ring I modified 4, 5-2-deoxystreptamine type aminoglycoside antibiotics
A Sonousi, A Vasella, D Crich
The Journal of organic chemistry 85 (11), 7583-7587, 2020
112020
Structure‐Activity Relationships for 5′′ Modifications of 4, 5‐Aminoglycoside Antibiotics
JCK Quirke, GC Sati, A Sonousi, M Gysin, K Haldimann, EC Böttger, ...
ChemMedChem 17 (13), e202200120, 2022
102022
Selective Protection of Secondary Amines as the N-Phenyltriazenes. Application to Aminoglycoside Antibiotics
A Sonousi, D Crich
Organic letters 17 (16), 4006-4009, 2015
102015
Design and synthesis of novel quinazolinone-based derivatives as EGFR inhibitors with antitumor activity
A Sonousi, RA Hassan, EO Osman, AM Abdou, SH Emam
Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 2644-2659, 2022
82022
New trends in synthetic drugs and natural products targeting 20S proteasomes in cancers
H Atta, N Alzahaby, NM Hamdy, SH Emam, A Sonousi, L Ziko
Bioorganic chemistry 133, 106427, 2023
72023
Design, synthesis, anticancer, and antibacterial evaluation of some quinazolinone‐based derivatives as DHFR inhibitors
EO Osman, SH Emam, A Sonousi, MM Kandil, AM Abdou, RA Hassan
Drug Development Research 84 (5), 888-906, 2023
62023
Synthesis, ribosomal selectivity, and antibacterial activity of netilmicin 4′-derivatives
A Sonousi, D Shcherbakov, A Vasella, EC Böttger, D Crich
MedChemComm 10 (6), 946-950, 2019
32019
Synthesis Of Netilmicin And Apramycin Derivatives For The Treatment Of Multidrug-Resistant Infectious Diseases
ASM Sonousi
22017
Design, synthesis, and biological evaluation of 1, 2, 4-oxadiazole-based derivatives as multitarget anti-Alzheimer agents
MS Ayoup, MR Barakat, H Abdel-Hamid, E Emam, YS Al-Faiyz, ...
RSC Medicinal Chemistry, 2024
2024
Novel sulfonamide derivatives as multitarget antidiabetic agents: design, synthesis, and biological evaluation
MS Ayoup, N Khaled, H Abdel-Hamid, DA Ghareeb, SA Nasr, A Omer, ...
RSC advances 14 (11), 7664-7675, 2024
2024
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