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Helgi Schiöth
Helgi Schiöth
Professor at Department of Neuroscience, Functional Pharmacology, Uppsala University
Verified email at neuro.uu.se
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Year
The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints
R Fredriksson, MC Lagerström, LG Lundin, HB Schiöth
Molecular pharmacology 63 (6), 1256-1272, 2003
39962003
Trends in GPCR drug discovery: new agents, targets and indications
AS Hauser, MM Attwood, M Rask-Andersen, HB Schiöth, DE Gloriam
Nature reviews Drug discovery 16 (12), 829-842, 2017
24852017
Structural diversity of G protein-coupled receptors and significance for drug discovery
MC Lagerström, HB Schiöth
Nature reviews Drug discovery 7 (4), 339-357, 2008
18852008
HMDB 5.0: the human metabolome database for 2022
DS Wishart, AC Guo, E Oler, F Wang, A Anjum, H Peters, R Dizon, ...
Nucleic acids research 50 (D1), D622-D631, 2022
12342022
Trends in the exploitation of novel drug targets
M Rask-Andersen, MS Almén, HB Schiöth
Nature reviews Drug discovery 10 (8), 579-590, 2011
10522011
Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin
MS Almén, KJV Nordström, R Fredriksson, HB Schiöth
BMC biology 7, 1-14, 2009
7822009
The repertoire of G-protein–coupled receptors in fully sequenced genomes
R Fredriksson, HB Schiöth
Molecular pharmacology 67 (5), 1414-1425, 2005
7692005
Comprehensive repertoire and phylogenetic analysis of the G protein-coupled receptors in human and mouse
TK Bjarnadóttir, DE Gloriam, SH Hellstrand, H Kristiansson, R Fredriksson, ...
Genomics 88 (3), 263-273, 2006
5722006
Trends in kinase drug discovery: targets, indications and inhibitor design
MM Attwood, D Fabbro, AV Sokolov, S Knapp, HB Schiöth
Nature Reviews Drug Discovery 20 (11), 839-861, 2021
5082021
The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain
R Fredriksson, M Hägglund, PK Olszewski, O Stephansson, ...
Endocrinology 149 (5), 2062-2071, 2008
4872008
International union of basic and clinical pharmacology. xciv. adhesion g protein–coupled receptors
J Hamann, G Aust, D Araç, FB Engel, C Formstone, R Fredriksson, ...
Pharmacological reviews 67 (2), 338-367, 2015
4782015
The GRAFS classification system of G-protein coupled receptors in comparative perspective
HB Schiöth, R Fredriksson
General and comparative endocrinology 142 (1-2), 94-101, 2005
4782005
Ghrelin increases anxiety-like behavior and memory retention in rats
VP Carlini, ME Monzón, MM Varas, AB Cragnolini, HB Schiöth, ...
Biochemical and biophysical research communications 299 (5), 739-743, 2002
4762002
Differential role of the hippocampus, amygdala, and dorsal raphe nucleus in regulating feeding, memory, and anxiety-like behavioral responses to ghrelin
VP Carlini, MM Varas, AB Cragnolini, HB Schiöth, TN Scimonelli, ...
Biochemical and biophysical research communications 313 (3), 635-641, 2004
4192004
Seven evolutionarily conserved human rhodopsin G protein‐coupled receptors lacking close relatives
R Fredriksson, PJ Höglund, DEI Gloriam, MC Lagerström, HB Schiöth
FEBS letters 554 (3), 381-388, 2003
3772003
The druggable genome: evaluation of drug targets in clinical trials suggests major shifts in molecular class and indication
M Rask-Andersen, S Masuram, HB Schiöth
Annual review of pharmacology and toxicology 54 (1), 9-26, 2014
3572014
Acute sleep deprivation enhances the brain's response to hedonic food stimuli: an fMRI study
C Benedict, SJ Brooks, OG O'Daly, MS Almen, A Morell, K Åberg, ...
The Journal of Clinical Endocrinology & Metabolism 97 (3), E443-E447, 2012
3522012
Intranasal treatment of central nervous system dysfunction in humans
CD Chapman, WH Frey, S Craft, L Danielyan, M Hallschmid, HB Schiöth, ...
Pharmaceutical research 30, 2475-2484, 2013
3432013
Acute sleep deprivation reduces energy expenditure in healthy men
C Benedict, M Hallschmid, A Lassen, C Mahnke, B Schultes, HB Schiöth, ...
The American journal of clinical nutrition 93 (6), 1229-1236, 2011
3382011
The human and mouse repertoire of the adhesion family of G-protein-coupled receptors
TK Bjarnadóttir, R Fredriksson, PJ Höglund, DE Gloriam, MC Lagerström, ...
Genomics 84 (1), 23-33, 2004
3172004
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