| Towards the sustainable discovery and development of new antibiotics M Miethke, M Pieroni, T Weber, M Brönstrup, P Hammann, L Halby, ... Nature Reviews Chemistry 5 (10), 726-749, 2021 | 572 | 2021 |
| Indoleamides are active against drug-resistant Mycobacterium tuberculosis S Lun, H Guo, OK Onajole, M Pieroni, H Gunosewoyo, G Chen, ... Nature communications 4 (1), 2907, 2013 | 152 | 2013 |
| Preliminary structure–activity relationships and biological evaluation of novel antitubercular indolecarboxamide derivatives against drug-susceptible and drug-resistant … OK Onajole, M Pieroni, SK Tipparaju, S Lun, J Stec, G Chen, ... Journal of medicinal chemistry 56 (10), 4093-4103, 2013 | 146 | 2013 |
| From serendipity to rational antituberculosis drug discovery of mefloquine-isoxazole carboxylic acid esters J Mao, H Yuan, Y Wang, B Wan, M Pieroni, Q Huang, RB Van Breemen, ... Journal of medicinal chemistry 52 (22), 6966-6978, 2009 | 121 | 2009 |
| Challenging the drug-likeness dogma for new drug discovery in tuberculosis D Machado, M Girardini, M Viveiros, M Pieroni Frontiers in microbiology 9, 383242, 2018 | 99 | 2018 |
| In Pursuit of Natural Product Leads: Synthesis and Biological Evaluation of 2-[3-hydroxy-2-[(3-hydroxypyridine-2-carbonyl) amino] phenyl] benzoxazole-4-carboxylic acid (A-33853 … SK Tipparaju, S Joyasawal, M Pieroni, M Kaiser, R Brun, AP Kozikowski Journal of medicinal chemistry 51 (23), 7344-7347, 2008 | 96 | 2008 |
| Pyrido[1,2‐a]benzimidazole‐Based Agents Active Against Tuberculosis (TB), Multidrug‐Resistant (MDR) TB and Extensively Drug‐Resistant (XDR) TB M Pieroni, SK Tipparaju, S Lun, Y Song, AW Sturm, WR Bishai, ... ChemMedChem 6 (2), 334-342, 2011 | 79 | 2011 |
| Design, synthesis and investigation on the structure–activity relationships of N-substituted 2-aminothiazole derivatives as antitubercular agents M Pieroni, B Wan, S Cho, SG Franzblau, G Costantino European journal of medicinal chemistry 72, 26-34, 2014 | 77 | 2014 |
| Rational Design of 5-Phenyl-3-isoxazolecarboxylic Acid Ethyl Esters as Growth Inhibitors of Mycobacterium tuberculosis. A Potent and Selective Series for Further … A Lilienkampf, M Pieroni, B Wan, Y Wang, SG Franzblau, AP Kozikowski Journal of medicinal chemistry 53 (2), 678-688, 2010 | 76 | 2010 |
| Substituted N-Phenyl-5-(2-(phenylamino)thiazol-4-yl)isoxazole-3-carboxamides Are Valuable Antitubercular Candidates that Evade Innate Efflux Machinery E Azzali, D Machado, A Kaushik, F Vacondio, S Flisi, CS Cabassi, ... Journal of medicinal chemistry 60 (16), 7108-7122, 2017 | 72 | 2017 |
| Modulation of bacterial metabolism by the microenvironment controls MAIT cell stimulation M Schmaler, A Colone, J Spagnuolo, M Zimmermann, M Lepore, ... Mucosal immunology 11 (4), 1060-1070, 2018 | 67 | 2018 |
| Inhibitors of the sulfur assimilation pathway in bacterial pathogens as enhancers of antibiotic therapy B Campanini, M Pieroni, S Raboni, S Bettati, R Benoni, C Pecchini, ... Current medicinal chemistry 22 (2), 187-213, 2015 | 65 | 2015 |
| Rational design and synthesis of thioridazine analogues as enhancers of the antituberculosis therapy M Pieroni, D Machado, E Azzali, S Santos Costa, I Couto, G Costantino, ... Journal of medicinal chemistry 58 (15), 5842-5853, 2015 | 58 | 2015 |
| Synthesis, Biological Evaluation, and Structure−Activity Relationships for 5-[(E)-2-Arylethenyl]-3-isoxazolecarboxylic Acid Alkyl Ester Derivatives as Valuable … M Pieroni, A Lilienkampf, B Wan, Y Wang, SG Franzblau, AP Kozikowski Journal of medicinal chemistry 52 (20), 6287-6296, 2009 | 55 | 2009 |
| Discovery of New Potential Anti‐Infective Compounds Based on Carbonic Anhydrase Inhibitors by Rational Target‐Focused Repurposing Approaches G Annunziato, A Angeli, F D'Alba, A Bruno, M Pieroni, D Vullo, V De Luca, ... ChemMedChem 11 (17), 1904-1914, 2016 | 54 | 2016 |
| Accepting the invitation to open innovation in malaria drug discovery: synthesis, biological evaluation, and investigation on the structure–activity relationships of benzo [b … M Pieroni, E Azzali, N Basilico, S Parapini, M Zolkiewski, C Beato, ... Journal of medicinal chemistry 60 (5), 1959-1970, 2017 | 48 | 2017 |
| Further insights into the SAR of α-substituted cyclopropylamine derivatives as inhibitors of histone demethylase KDM1A M Pieroni, G Annunziato, E Azzali, P Dessanti, C Mercurio, G Meroni, ... European journal of medicinal chemistry 92, 377-386, 2015 | 46 | 2015 |
| Synthesis, Biological Evaluation, and Structure–Activity Relationships of N-Benzoyl-2-hydroxybenzamides as Agents Active against P. falciparum (K1 strain … J Stec, Q Huang, M Pieroni, M Kaiser, A Fomovska, E Mui, WH Witola, ... Journal of medicinal chemistry 55 (7), 3088-3100, 2012 | 46 | 2012 |
| From 6-Aminoquinolone Antibacterials to 6-Amino-7-thiopyranopyridinylquinolone Ethyl Esters as Inhibitors of Staphylococcus aureus Multidrug Efflux Pumps M Pieroni, M Dimovska, JP Brincat, S Sabatini, E Carosati, S Massari, ... Journal of medicinal chemistry 53 (11), 4466-4480, 2010 | 43 | 2010 |
| ‘Heteroaromatic Rings of the Future’: Exploration of Unconquered Chemical Space K Passador, S Thorimbert, C Botuha Synthesis 51 (02), 384-398, 2019 | 40 | 2019 |
