Joanna Holbrook
Joanna Holbrook
CSO, Cambridge Epigenetix
Verified email at - Homepage
Cited by
Cited by
Resistin is expressed in human macrophages and directly regulated by PPARγ activators
L Patel, AC Buckels, IJ Kinghorn, PR Murdock, JD Holbrook, C Plumpton, ...
Biochemical and biophysical research communications 300 (2), 472-476, 2003
Cohort profile: Growing Up in Singapore Towards healthy Outcomes (GUSTO) birth cohort study
SE Soh, MT Tint, PD Gluckman, KM Godfrey, A Rifkin-Graboi, YH Chan, ...
International journal of epidemiology 43 (5), 1401-1409, 2014
Applications of machine learning to diagnosis and treatment of neurodegenerative diseases
MA Myszczynska, PN Ojamies, AMB Lacoste, D Neil, A Saffari, R Mead, ...
Nature Reviews Neurology 16 (8), 440-456, 2020
The effect of genotype and in utero environment on interindividual variation in neonate DNA methylomes
AL Teh, H Pan, L Chen, ML Ong, S Dogra, J Wong, JL MacIsaac, SM Mah, ...
Genome research 24 (7), 1064-1074, 2014
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
N Kato, M Loh, F Takeuchi, N Verweij, X Wang, W Zhang, TN Kelly, ...
Nature genetics 47 (11), 1282-1293, 2015
Dynamics of infant gut microbiota are influenced by delivery mode and gestational duration and are associated with subsequent adiposity
S Dogra, O Sakwinska, SE Soh, C Ngom-Bru, WM Brück, B Berger, ...
MBio 6 (1), 10.1128/mbio. 02419-14, 2015
Human lymphocytes interact directly with CD47 through a novel member of the signal regulatory protein (SIRP) family
G Brooke, JD Holbrook, MH Brown, AN Barclay
The Journal of Immunology 173 (4), 2562-2570, 2004
Developmental pathways to adiposity begin before birth and are influenced by genotype, prenatal environment and epigenome
X Lin, IY Lim, Y Wu, AL Teh, L Chen, IM Aris, SE Soh, MT Tint, ...
BMC medicine 15, 1-18, 2017
Comprehensive predictive biomarker analysis for MEK inhibitor GSK1120212
J Jing, J Greshock, JD Holbrook, A Gilmartin, X Zhang, E McNeil, ...
Molecular cancer therapeutics 11 (3), 720-729, 2012
The translational value of rodent gastrointestinal functions: a cautionary tale
GJ Sanger, JD Holbrook, PLR Andrews
Trends in pharmacological sciences 32 (7), 402-409, 2011
Rate of establishing the gut microbiota in infancy has consequences for future health
S Dogra, O Sakwinska, SE Soh, C Ngom-Bru, WM Brück, B Berger, ...
Gut microbes 6 (5), 321-325, 2015
Deep sequencing of gastric carcinoma reveals somatic mutations relevant to personalized medicine
JD Holbrook, JS Parker, KT Gallagher, WS Halsey, AM Hughes, ...
Journal of translational medicine 9, 1-13, 2011
Effects of antenatal maternal depressive symptoms and socio-economic status on neonatal brain development are modulated by genetic risk
A Qiu, M Shen, C Buss, YS Chong, K Kwek, SM Saw, PD Gluckman, ...
Cerebral cortex 27 (5), 3080-3092, 2017
COMT haplotypes modulate associations of antenatal maternal anxiety and neonatal cortical morphology
A Qiu, TA Tuan, ML Ong, Y Li, H Chen, A Rifkin-Graboi, BFP Broekman, ...
American Journal of Psychiatry 172 (2), 163-172, 2015
Identification of genes for the ghrelin and motilin receptors and a novel related gene in fish, and stimulation of intestinal motility in zebrafish (Danio rerio) by ghrelin and …
C Olsson, JD Holbrook, G Bompadre, E Jönsson, CHV Hoyle, GJ Sanger, ...
General and Comparative Endocrinology 155 (1), 217-226, 2008
Characterisation of 5‐HT3C, 5‐HT3D and 5‐HT3E receptor subunits: evolution, distribution and function
JD Holbrook, CH Gill, N Zebda, JP Spencer, R Leyland, KH Rance, ...
Journal of neurochemistry 108 (2), 384-396, 2009
Genome-wide methylation analysis identifies differentially methylated CpG loci associated with severe obesity in childhood
RC Huang, ES Garratt, H Pan, Y Wu, EA Davis, SJ Barton, GC Burdge, ...
Epigenetics 10 (11), 995-1005, 2015
Novel region discovery method for Infinium 450K DNA methylation data reveals changes associated with aging in muscle and neuronal pathways
ML Ong, JD Holbrook
Aging cell 13 (1), 142-155, 2014
Maternal smoking during pregnancy induces persistent epigenetic changes into adolescence, independent of postnatal smoke exposure and is associated with cardiometabolic risk
S Rauschert, PE Melton, G Burdge, JM Craig, KM Godfrey, JD Holbrook, ...
Frontiers in genetics 10, 770, 2019
Global DNA hypermethylation in down syndrome placenta
S Jin, YK Lee, YC Lim, Z Zheng, XM Lin, DPY Ng, JD Holbrook, HY Law, ...
PLoS genetics 9 (6), e1003515, 2013
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