Interplay between metabolic identities in the intestinal crypt supports stem cell function MJ Rodríguez-Colman, M Schewe, M Meerlo, E Stigter, J Gerrits, ... Nature 543 (7645), 424-427, 2017 | 460 | 2017 |
TGFβ-induced metabolic reprogramming during epithelial-to-mesenchymal transition in cancer W Hua, P Ten Dijke, S Kostidis, M Giera, M Hornsveld Cellular and Molecular Life Sciences 77, 2103-2123, 2020 | 182 | 2020 |
Re-evaluating the role of FOXOs in cancer M Hornsveld, TB Dansen, PW Derksen, BMT Burgering Seminars in cancer biology 50, 90-100, 2018 | 161 | 2018 |
Mammary-specific inactivation of E-cadherin and p53 impairs functional gland development and leads to pleomorphic invasive lobular carcinoma in mice PWB Derksen, TM Braumuller, E van der Burg, M Hornsveld, E Mesman, ... Disease models & mechanisms 4 (3), 347-358, 2011 | 149 | 2011 |
The hallmarks of cancer from a redox perspective M Hornsveld, TB Dansen Antioxidants & redox signaling 25 (6), 300-325, 2016 | 110 | 2016 |
Genes involved in centrosome-independent mitotic spindle assembly in Drosophila S2 cells S Moutinho-Pereira, N Stuurman, O Afonso, M Hornsveld, P Aguiar, ... Proceedings of the National Academy of Sciences 110 (49), 19808-19813, 2013 | 80 | 2013 |
FOXO transcription factors both suppress and support breast cancer progression M Hornsveld, LMM Smits, M Meerlo, M Van Amersfoort, ... Cancer research 78 (9), 2356-2369, 2018 | 74 | 2018 |
Assessment of functional phosphatidylinositol 3-kinase pathway activity in cancer tissue using forkhead box-O target gene expression in a knowledge-based computational model H Van Ooijen, M Hornsveld, C Dam-de Veen, R Velter, M Dou, ... The American journal of pathology 188 (9), 1956-1972, 2018 | 56 | 2018 |
FOXO s support the metabolic requirements of normal and tumor cells by promoting IDH 1 expression P Charitou, M Rodriguez‐Colman, J Gerrits, M van Triest, ... EMBO reports 16 (4), 456-466, 2015 | 49 | 2015 |
Restraining FOXO3-dependent transcriptional BMF activation underpins tumour growth and metastasis of E-cadherin-negative breast cancer M Hornsveld, M Tenhagen, RA Van de Ven, AMM Smits, MH Van Triest, ... Cell Death & Differentiation 23 (9), 1483-1492, 2016 | 47 | 2016 |
A FOXO-dependent replication checkpoint restricts proliferation of damaged cells M Hornsveld, FM Feringa, L Krenning, J van den Berg, LMM Smits, ... Cell Reports 34 (4), 2021 | 12 | 2021 |
Nonhuman primate adenoviruses of the human adenovirus B species are potent and broadly acting oncolytic vector candidates STF Bots, V Kemp, SJ Cramer, DJM van den Wollenberg, M Hornsveld, ... Human Gene Therapy 33 (5-6), 275-289, 2022 | 10 | 2022 |
Dynamic visualization of TGF-β/SMAD3 transcriptional responses in single living cells DL Marvin, L You, L Bornes, M van Dinther, N Peters, H Dang, SK Hakuno, ... Cancers 14 (10), 2508, 2022 | 9 | 2022 |
A novel pancreatic cancer mini-tumor model to study desmoplasia and myofibroblastic cancer-associated fibroblast differentiation TJ Harryvan, L Hawinkels, A Inderson, JE van Hooft, P Micke, ... Gastro Hep Advances 1 (4), 678-681, 2022 | 9 | 2022 |
Metabolic Reprogramming of Mammary Epithelial Cells during TGF-β-Induced Epithelial-to-Mesenchymal Transition W Hua, S Kostidis, O Mayboroda, M Giera, M Hornsveld, P Ten Dijke Metabolites 11 (9), 626, 2021 | 9 | 2021 |
Gastrointestinal cancer-associated fibroblasts expressing Junctional Adhesion Molecule-A are amenable to infection by oncolytic reovirus TJ Harryvan, M Golo, N Dam, MJA Schoonderwoerd, EA Farshadi, ... Cancer Gene Therapy 29 (12), 1918-1929, 2022 | 6 | 2022 |
SKOR1 mediates FER kinase-dependent invasive growth of breast cancer cells LM Sluimer, E Bullock, MAK Rätze, L Enserink, C Overbeeke, ... Journal of Cell Science 136 (3), jcs260243, 2023 | 4 | 2023 |
Abstract LB435: Large panel organoid drug testing combined with biomarker analysis: Unveiling prospects for mechanism of action identification and preclinical patient … L Xue, L Wijler, M Hornsveld, S Guo, L Price, M Putker, L Bourre Cancer Research 84 (7_Supplement), LB435-LB435, 2024 | | 2024 |
Mini-tumors: Pre-clinical HCI assays to screen anti-cancer drugs in the context of organoids, cancer-associated fibroblasts and immune cells M Hornsveld, G Odenkirchen, C van Dort, JG Mateos, S de Man, ... Cancer Research 83 (7_Supplement), 579-579, 2023 | | 2023 |
High content screening of ovarian organoid models to accelerate anti-cancer drug discovery M Hornsveld, M Madej, JG Mateos, G Goverse, M Putker, E Spanjaard, ... European Journal of Cancer 174, S114, 2022 | | 2022 |