|Sulindac Selectively Inhibits Colon Tumor Cell Growth by Activating the cGMP/PKG Pathway to Suppress Wnt/β-Catenin SignalingPDE5 Inhibition Selectively Inhibits Colon Tumor …|
N Li, Y Xi, HN Tinsley, E Gurpinar, BD Gary, B Zhu, Y Li, X Chen, ...
Molecular cancer therapeutics 12 (9), 1848-1859, 2013
|Therapeutically targeting glypican-2 via single-domain antibody-based chimeric antigen receptors and immunotoxins in neuroblastoma|
N Li, H Fu, SM Hewitt, DS Dimitrov, M Ho
Proceedings of the National Academy of Sciences 114 (32), E6623-E6631, 2017
|Glypicans as cancer therapeutic targets|
N Li, W Gao, YF Zhang, M Ho
Trends in cancer 4 (11), 741-754, 2018
|Colon Tumor Cell Growth–Inhibitory Activity of Sulindac Sulfide and Other Nonsteroidal Anti-Inflammatory Drugs Is Associated with Phosphodiesterase 5 InhibitionSulindac …|
HN Tinsley, BD Gary, J Thaiparambil, N Li, W Lu, Y Li, YY Maxuitenko, ...
Cancer Prevention Research 3 (10), 1303-1313, 2010
|A Novel Sulindac Derivative that Potently Suppresses Colon Tumor Cell Growth by Inhibiting cGMP Phosphodiesterase and β-Catenin Transcriptional ActivitycGMP PDE Inhibition by a …|
JD Whitt, N Li, HN Tinsley, X Chen, W Zhang, Y Li, BD Gary, AB Keeton, ...
Cancer prevention research 5 (6), 822-833, 2012
|Persistent polyfunctional chimeric antigen receptor T cells that target glypican 3 eliminate orthotopic hepatocellular carcinomas in mice|
D Li, N Li, YF Zhang, H Fu, M Feng, D Schneider, L Su, X Wu, J Zhou, ...
Gastroenterology 158 (8), 2250-2265. e20, 2020
|A Frizzled‐Like Cysteine‐Rich Domain in Glypican‐3 Mediates Wnt Binding and Regulates Hepatocellular Carcinoma Tumor Growth in Mice|
N Li, L Wei, X Liu, H Bai, Y Ye, D Li, N Li, U Baxa, Q Wang, L Lv, Y Chen, ...
Hepatology 70 (4), 1231-1245, 2019
|Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and β-catenin-dependent TCF transcriptional activity|
N Li, K Lee, Y Xi, B Zhu, BD Gary, V Ramírez-Alcántara, E Gurpinar, ...
Oncogene 34 (12), 1499-1509, 2015
|Glypican‐3‐specific antibody drug conjugates targeting hepatocellular carcinoma|
Y Fu, DJ Urban, RR Nani, YF Zhang, N Li, H Fu, H Shah, AP Gorka, ...
Hepatology 70 (2), 563-576, 2019
|β-catenin nuclear translocation in colorectal cancer cells is suppressed by PDE10A inhibition, cGMP elevation, and activation of PKG|
K Lee, AS Lindsey, N Li, B Gary, J Andrews, AB Keeton, GA Piazza
Oncotarget 7 (5), 5353, 2016
|A Novel Sulindac Derivative Inhibits Lung Adenocarcinoma Cell Growth through Suppression of Akt/mTOR Signaling and Induction of AutophagyNovel Sulindac Analog Induces Autophagy …|
E Gurpinar, WE Grizzle, JJ Shacka, BJ Mader, N Li, NA Piazza, S Russo, ...
Molecular cancer therapeutics 12 (5), 663-674, 2013
|Suppression of β-catenin/TCF transcriptional activity and colon tumor cell growth by dual inhibition of PDE5 and 10|
N Li, X Chen, B Zhu, V Ramírez-Alcántara, JC Canzoneri, K Lee, S Sigler, ...
Oncotarget 6 (29), 27403, 2015
|The role of glypicans in cancer progression and therapy|
N Li, MR Spetz, M Ho
Journal of Histochemistry & Cytochemistry 68 (12), 841-862, 2020
|Novel non-cyclooxygenase inhibitory derivatives of naproxen for colorectal cancer chemoprevention|
T Aboul-Fadl, SS Al-Hamad, K Lee, N Li, BD Gary, AB Keeton, GA Piazza, ...
Medicinal Chemistry Research 23 (9), 4177-4188, 2014
|Phosphodiesterase 10A is overexpressed in lung tumor cells and inhibitors selectively suppress growth by blocking β-catenin and MAPK signaling|
B Zhu, A Lindsey, N Li, K Lee, V Ramirez-Alcantara, JC Canzoneri, ...
Oncotarget 8 (41), 69264, 2017
|Shed antigen-induced blocking effect on CAR-T cells targeting Glypican-3 in Hepatocellular Carcinoma|
L Sun, F Gao, Z Gao, L Ao, N Li, S Ma, M Jia, N Li, P Lu, B Sun, M Ho, ...
Journal for immunotherapy of cancer 9 (4), 2021
|CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice|
N Li, MB Torres, MR Spetz, R Wang, L Peng, M Tian, CM Dower, ...
Cell Reports Medicine 2 (6), 100297, 2021
|Advances in immunotherapeutic targets for childhood cancers: A focus on glypican-2 and B7-H3|
N Li, MR Spetz, D Li, M Ho
Pharmacology & Therapeutics 223, 107892, 2021
|GPC1-targeted immunotoxins inhibit pancreatic tumor growth in mice via depletion of short-lived GPC1 and downregulation of Wnt signaling|
J Pan, N Li, A Renn, H Zhu, L Chen, M Shen, MD Hall, M Qian, I Pastan, ...
Molecular Cancer Therapeutics 21 (6), 960-973, 2022
|Preclinical testing of chimeric antigen receptor T cells in neuroblastoma mouse models|
N Li, R Nguyen, CJ Thiele, M Ho
STAR protocols 2 (4), 100942, 2021