| New benzoxazole derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: Design, synthesis, anti-proliferative evaluation, flowcytometric analysis, and in silico studies H Elkady, A Elwan, HA El-Mahdy, AS Doghish, A Ismail, MS Taghour, ... Journal of enzyme inhibition and medicinal chemistry 37 (1), 403-416, 2022 | 106 | 2022 |
| Discovery of thieno [2, 3-d] pyrimidine-based derivatives as potent VEGFR-2 kinase inhibitors and anti-cancer agents SA El-Metwally, MM Abou-El-Regal, IH Eissa, ABM Mehany, HA Mahdy, ... Bioorganic Chemistry 112, 104947, 2021 | 87 | 2021 |
| Design, synthesis, docking, ADMET studies, and anticancer evaluation of new 3-methylquinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers MM Alanazi, IH Eissa, NA Alsaif, AJ Obaidullah, WA Alanazi, AF Alasmari, ... Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 1760-1782, 2021 | 70 | 2021 |
| Design, synthesis, molecular docking and anti-proliferative evaluations of [1, 2, 4] triazolo [4, 3-a] quinoxaline derivatives as DNA intercalators and Topoisomerase II inhibitors K El-Adl, AGA El-Helby, H Sakr, A Elwan Bioorganic Chemistry 105, 104399, 2020 | 54 | 2020 |
| Discovery of new VEGFR-2 inhibitors based on bis([1, 2, 4]triazolo)[4,3-a:3',4'-c]quinoxaline derivatives as anticancer agents and apoptosis inducers NA Alsaif, MS Taghour, MM Alanazi, AJ Obaidullah, AA Al-Mehizia, ... Journal of enzyme inhibition and medicinal chemistry 36 (1), 1093-1114, 2021 | 46 | 2021 |
| A multistage in silico study of natural potential inhibitors targeting SARS-CoV-2 main protease EB Elkaeed, IH Eissa, H Elkady, A Abdelalim, AM Alqaisi, AA Alsfouk, ... International Journal of Molecular Sciences 23 (15), 8407, 2022 | 41 | 2022 |
| Discovery of new 3-methylquinoxalines as potential anti-cancer agents and apoptosis inducers targeting VEGFR-2: design, synthesis, and in silico studies MM Alanazi, A Elwan, NA Alsaif, AJ Obaidullah, HM Alkahtani, ... Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 1732-1750, 2021 | 40 | 2021 |
| [1, 2, 4] Triazolo [4, 3-a] quinoxaline and [1, 2, 4] triazolo [4, 3-a] quinoxaline-1-thiol-derived DNA intercalators: design, synthesis, molecular docking, in silico ADMET … K El-Adl, AGA El-Helby, H Sakr, A Elwan New journal of chemistry 45 (2), 881-897, 2021 | 39 | 2021 |
| Design, molecular docking and synthesis of some novel 4-acetyl-1-substituted-3,4-dihydroquinoxalin-2(1H)-one derivatives for anticonvulsant evaluation as AMPA … AGA El-Helby, RRA Ayyad, K El-Adl, H Sakr, AA Abd-Elrahman, IH Eissa, ... Medicinal Chemistry Research 25, 3030-3046, 2016 | 38 | 2016 |
| Modified benzoxazole-based VEGFR-2 inhibitors and apoptosis inducers: Design, synthesis, and anti-proliferative evaluation A Elwan, AE Abdallah, HA Mahdy, MA Dahab, MS Taghour, EB Elkaeed, ... Molecules 27 (15), 5047, 2022 | 33 | 2022 |
| Quinoxalin-2(1H)-one derived AMPA-receptor antagonists: Design, synthesis, molecular docking and anticonvulsant activity AGA El-Helby, RRA Ayyad, K El-Adl, A Elwan Medicinal Chemistry Research 26, 2967-2984, 2017 | 33 | 2017 |
| Benzoxazole derivatives as new VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, in silico studies, and antiproliferative evaluation MS Taghour, HA Mahdy, MH Gomaa, A Aglan, MG Eldeib, A Elwan, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 2063-2077, 2022 | 30 | 2022 |
| Anti-cancer and immunomodulatory evaluation of new nicotinamide derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: in vitro and in silico studies RG Yousef, A Elwan, IMM Gobaara, ABM Mehany, WM Eldehna, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 2206-2222, 2022 | 26 | 2022 |
| Design, synthesis and molecular docking of new [1, 2, 4] triazolo [4, 3-a] quinoxaline derivatives as anticancer agents targeting VEGFR-2 kinase NA Alsaif, A Elwan, MM Alanazi, AJ Obaidullah, WA Alanazi, AF Alasmari, ... Molecular Diversity 26 (4), 1915-1932, 2022 | 15 | 2022 |
| Structure‐Based virtual screening, docking, ADMET, molecular dynamics, and MM‐PBSA calculations for the discovery of potential natural SARS‐CoV‐2 helicase inhibitors from the … AM Metwaly, A Elwan, AAMM El-Attar, ST Al-Rashood, IH Eissa Journal of Chemistry 2022 (1), 7270094, 2022 | 15 | 2022 |
| Targeting VEGFR‐2 by new quinoxaline derivatives: Design, synthesis, antiproliferative assay, apoptosis induction, and in silico studies NA Alsaif, HA Mahdy, MM Alanazi, AJ Obaidullah, HM Alkahtani, ... Archiv der Pharmazie 355 (2), 2100359, 2022 | 14 | 2022 |
| Design, synthesis, in silico and in vitro studies of new immunomodulatory anticancer nicotinamide derivatives targeting VEGFR-2 RG Yousef, WM Eldehna, A Elwan, AS Abdelaziz, ABM Mehany, ... Molecules 27 (13), 4079, 2022 | 11 | 2022 |
| New theobromine derivatives inhibiting VEGFR-2: design, synthesis, antiproliferative, docking and molecular dynamics simulations HA Mahdy, H Elkady, MS Taghour, A Elwan, MA Dahab, MA Elkady, ... Future Medicinal Chemistry 15 (14), 1233-1250, 2023 | 10 | 2023 |
| Design, synthesis, molecular modeling and biological evaluation of novel Benzoxazole-Benzamide conjugates via a 2-Thioacetamido linker as potential anti … IH Eissa, R El-Haggar, MA Dahab, MF Ahmed, HA Mahdy, RI Alsantali, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 1587-1599, 2022 | 10 | 2022 |
| Semi-synthesized anticancer theobromine derivatives targeting VEGFR-2: in silico and in vitro evaluations MA Dahab, HA Mahdy, H Elkady, MS Taghour, A Elwan, MA Elkady, ... Journal of Biomolecular Structure and Dynamics 42 (8), 4214-4233, 2024 | 9 | 2024 |
