Ligand substitutions between ruthenium–cymene compounds can control protein versus DNA targeting and anticancer activity Z Adhireksan, GE Davey, P Campomanes, M Groessl, CM Clavel, H Yu, ... Nature communications 5 (1), 3462, 2014 | 320 | 2014 |
Antiproliferative activity of chelating N, O-and N, N-ruthenium (II) arene functionalised poly (propyleneimine) dendrimer scaffolds P Govender, AK Renfrew, CM Clavel, PJ Dyson, B Therrien, GS Smith Dalton Transactions 40 (5), 1158-1167, 2011 | 172 | 2011 |
Naphthalimide-tagged ruthenium–arene anticancer complexes: combining coordination with intercalation KJ Kilpin, CM Clavel, F Edafe, PJ Dyson Organometallics 31 (20), 7031-7039, 2012 | 163 | 2012 |
Modulating the anticancer activity of ruthenium (II)–arene complexes CM Clavel, E Paunescu, P Nowak-Sliwinska, AW Griffioen, R Scopelliti, ... Journal of medicinal chemistry 58 (8), 3356-3365, 2015 | 109 | 2015 |
Exploring the versatility of cycloplatinated thiosemicarbazones as antitumor and antiparasitic agents P Chellan, KM Land, A Shokar, A Au, SH An, CM Clavel, PJ Dyson, ... Organometallics 31 (16), 5791-5799, 2012 | 94 | 2012 |
Ruthenium (II) arene PTA (RAPTA) complexes: impact of enantiomerically pure chiral ligands KJ Kilpin, SM Cammack, CM Clavel, PJ Dyson Dalton Transactions 42 (6), 2008-2014, 2013 | 83 | 2013 |
Cytotoxicity of ruthenium–arene complexes containing β-ketoamine ligands R Pettinari, C Pettinari, F Marchetti, CM Clavel, R Scopelliti, PJ Dyson Organometallics 32 (1), 309-316, 2013 | 78 | 2013 |
Discovery of a highly tumor-selective organometallic ruthenium (II)–arene complex CM Clavel, E Paunescu, P Nowak-Sliwinska, AW Griffioen, R Scopelliti, ... Journal of medicinal chemistry 57 (8), 3546-3558, 2014 | 77 | 2014 |
Neutral and cationic multinuclear half-sandwich rhodium and iridium complexes coordinated to poly (propyleneimine) dendritic scaffolds: Synthesis and cytotoxicity R Payne, P Govender, B Therrien, CM Clavel, PJ Dyson, GS Smith Journal of Organometallic Chemistry 729, 20-27, 2013 | 77 | 2013 |
Thermoresponsive organometallic arene ruthenium complexes for tumour targeting CM Clavel, E Păunescu, P Nowak-Sliwinska, PJ Dyson Chemical Science 5 (3), 1097-1101, 2014 | 70 | 2014 |
Thiolato gold (I) complexes containing water-soluble phosphane ligands: a characterization of their chemical and biological properties E Vergara, E Cerrada, C Clavel, A Casini, M Laguna Dalton Transactions 40 (41), 10927-10935, 2011 | 67 | 2011 |
Synthesis, structure, and antiproliferative activity of ruthenium (II) arene complexes with N, O-chelating pyrazolone-based β-ketoamine ligands R Pettinari, F Marchetti, C Pettinari, A Petrini, R Scopelliti, CM Clavel, ... Inorganic Chemistry 53 (24), 13105-13111, 2014 | 63 | 2014 |
The influence of RAPTA moieties on the antiproliferative activity of peripheral-functionalised poly (salicylaldiminato) metallodendrimers P Govender, LC Sudding, CM Clavel, PJ Dyson, B Therrien, GS Smith Dalton Transactions 42 (4), 1267-1277, 2013 | 63 | 2013 |
Synthesis, characterization and in vitro anticancer activity of highly cytotoxic trithiolato diruthenium complexes of the type [(η6-p-MeC6H4iPr)2Ru2(μ2-SR1)2(μ2-SR2)]+ … F Giannini, J Furrer, G Suess-Fink, CM Clavel, PJ Dyson Journal of Organometallic Chemistry 744, 41-48, 2013 | 58 | 2013 |
Thermoresponsive chlorambucil derivatives for tumour targeting CM Clavel, O Zava, F Schmitt, BH Kenzaoui, AA Nazarov, ... Angewandte Chemie 31 (123), 7262-7265, 2011 | 33 | 2011 |
Antiangiogenic and Anticancer Properties of Bifunctional Ruthenium(II)–p-Cymene Complexes: Influence of Pendant Perfluorous Chains P Nowak-Sliwinska, CM Clavel, E Păunescu, MT Te Winkel, ... Molecular pharmaceutics 12 (8), 3089-3096, 2015 | 31 | 2015 |
Evaluation of the in vitro anticancer activity of cyclometalated half-sandwich rhodium and iridium complexes coordinated to naphthaldimine-based poly (propyleneimine) dendritic … LC Sudding, R Payne, P Govender, F Edafe, CM Clavel, PJ Dyson, ... Journal of Organometallic Chemistry 774, 79-85, 2014 | 30 | 2014 |
Synthesis, Characterisation and In Vitro Anticancer Activity of Hexanuclear Thiolato‐Bridged Arene Ruthenium Metalla‐Prisms MA Furrer, A Garci, E Denoyelle‐Di‐Muro, P Trouillas, F Giannini, J Furrer, ... Chemistry–A European Journal 19 (9), 3198-3203, 2013 | 30 | 2013 |
Anticancer Organometallic Osmium(II)‐p‐cymene Complexes E Păunescu, P Nowak‐Sliwinska, CM Clavel, R Scopelliti, AW Griffioen, ... ChemMedChem 10 (9), 1539-1547, 2015 | 26 | 2015 |
In vivo evaluation of small-molecule thermoresponsive anticancer drugs potentiated by hyperthermia CM Clavel, P Nowak-Sliwinska, E Păunescu, AW Griffioen, PJ Dyson Chemical Science 6 (5), 2795-2801, 2015 | 25 | 2015 |