Coexistence of passive and carrier-mediated processes in drug transport K Sugano, M Kansy, P Artursson, A Avdeef, S Bendels, L Di, GF Ecker, ... Nature reviews Drug discovery 9 (8), 597-614, 2010 | 729 | 2010 |
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes F Wohnsland, B Faller Journal of medicinal chemistry 44 (6), 923-930, 2001 | 637 | 2001 |
Alkylamides from Echinacea are a new class of cannabinomimetics: cannabinoid type 2 receptor-dependent and-independent immunomodulatory effects S Raduner, A Majewska, JZ Chen, XQ Xie, J Hamon, B Faller, ... Journal of Biological Chemistry 281 (20), 14192-14206, 2006 | 374 | 2006 |
PAMPA—critical factors for better predictions of absorption A Avdeef, S Bendels, L Di, B Faller, M Kansy, K Sugano, Y Yamauchi Journal of pharmaceutical sciences 96 (11), 2893-2909, 2007 | 272 | 2007 |
Modeling promiscuity based on in vitro safety pharmacology profiling data K Azzaoui, J Hamon, B Faller, S Whitebread, E Jacoby, A Bender, ... ChemMedChem: Chemistry Enabling Drug Discovery 2 (6), 874-880, 2007 | 210 | 2007 |
Drug permeability profiling using cell-free permeation tools: Overview and applications P Berben, A Bauer-Brandl, M Brandl, B Faller, GE Flaten, AC Jacobsen, ... European Journal of Pharmaceutical Sciences 119, 219-233, 2018 | 207 | 2018 |
Computational approaches to determine drug solubility B Faller, P Ertl Advanced drug delivery reviews 59 (7), 533-545, 2007 | 198 | 2007 |
Evidence-based approach to assess passive diffusion and carrier-mediated drug transport L Di, P Artursson, A Avdeef, GF Ecker, B Faller, H Fischer, JB Houston, ... Drug discovery today 17 (15-16), 905-912, 2012 | 196 | 2012 |
Passive lipoidal diffusion and carrier-mediated cell uptake are both important mechanisms of membrane permeation in drug disposition D Smith, P Artursson, A Avdeef, L Di, GF Ecker, B Faller, JB Houston, ... Molecular pharmaceutics 11 (6), 1727-1738, 2014 | 149 | 2014 |
4‐[3, 5‐Bis (2‐hydroxyphenyl)‐1, 2, 4‐triazol‐1‐yl]‐benzoic acid: a novel efficient and selective iron (III) complexing agent U Heinz, K Hegetschweiler, P Acklin, B Faller, R Lattmann, HP Schnebli Angewandte Chemie International Edition 38 (17), 2568-2570, 1999 | 148 | 1999 |
Artificial membrane assays to assess permeability B Faller Current drug metabolism 9 (9), 886-892, 2008 | 120 | 2008 |
Metabolic soft spot identification and compound optimization in early discovery phases using MetaSite and LC-MS/MS validation M Trunzer, B Faller, A Zimmerlin Journal of medicinal chemistry 52 (2), 329-335, 2009 | 118 | 2009 |
What is modulating solubility in simulated intestinal fluids? G Ottaviani, DJ Gosling, C Patissier, S Rodde, L Zhou, B Faller European journal of pharmaceutical sciences 41 (3-4), 452-457, 2010 | 117 | 2010 |
The Identification of Indacaterol as an Ultralong-Acting Inhaled β2-Adrenoceptor Agonist F Baur, D Beattie, D Beer, D Bentley, M Bradley, I Bruce, SJ Charlton, ... Journal of medicinal chemistry 53 (9), 3675-3684, 2010 | 115 | 2010 |
Heparin-induced conformational change and activation of mucus proteinase inhibitor B Faller, Y Mely, D Gerard, JG Bieth Biochemistry 31 (35), 8285-8290, 1992 | 104 | 1992 |
CYP3A time-dependent inhibition risk assessment validated with 400 reference drugs A Zimmerlin, M Trunzer, B Faller Drug Metabolism and Disposition 39 (6), 1039-1046, 2011 | 93 | 2011 |
ICL670A: preclinical profile H Nick, A Wong, P Acklin, B Faller, Y Jin, R Lattmann, T Sergejew, ... Iron Chelation Therapy, 185-203, 2002 | 93 | 2002 |
Heparin strongly decreases the rate of inhibition of neutrophil elastase by alpha 1-proteinase inhibitor KJ Frommherz, B Faller, JG Bieth Journal of Biological Chemistry 266 (23), 15356-15362, 1991 | 93 | 1991 |
Finasteride: A slow-binding 5. alpha.-reductase inhibitor B Faller, D Farley, H Nick Biochemistry 32 (21), 5705-5710, 1993 | 88 | 1993 |
New approach to measure protein binding based on a parallel artificial membrane assay and human serum albumin E Lázaro, PJ Lowe, X Briand, B Faller Journal of medicinal chemistry 51 (7), 2009-2017, 2008 | 77 | 2008 |