| Sphingosine kinase 1: A new modulator of hypoxia inducible factor 1α during hypoxia in human cancer cells I Ader, L Brizuela, P Bouquerel, B Malavaud, O Cuvillier Cancer research 68 (20), 8635-8642, 2008 | 173 | 2008 |
| Revisiting the Hallmarks of Aging to Identify Markers of Biological Age F Guerville, PDS Barreto, I Ader, S Andrieu, Casteilla, C Dray, N Fazilleau, ... JPAD- Journal of prevention of Alzheimers disease 7 (1), 56-64, 2020 | 100 | 2020 |
| Human adipose stromal-vascular fraction self-organizes to form vascularized adipose tissue in 3D cultures S Muller, I Ader, J Creff, H Leménager, P Achard, L Casteilla, L Sensebé, ... Scientific reports 9 (1), 7250, 2019 | 98 | 2019 |
| When the sphingosine kinase 1/sphingosine 1-phosphate pathway meets hypoxia signaling: new targets for cancer therapy I Ader, B Malavaud, O Cuvillier Cancer research 69 (9), 3723-3726, 2009 | 96 | 2009 |
| RhoB controls the 24 kDa FGF-2-induced radioresistance in HeLa cells by preventing post-mitotic cell death I Ader, C Toulas, F Dalenc, C Delmas, J Bonnet, E Cohen-Jonathan, ... Oncogene 21 (39), 5998-6006, 2002 | 92 | 2002 |
| The sphingosine kinase‐1 survival pathway is a molecular target for the tumor‐suppressive tea and wine polyphenols in prostate cancer L Brizuela, A Dayon, N Doumerc, I Ader, M Golzio, JC Izard, Y Hara, ... The FASEB Journal 24 (10), 3882-3894, 2010 | 90 | 2010 |
| Activation of sphingosine kinase-1 in cancer: implications for therapeutic targeting O Cuvillier, I Ader, P Bouquerel, L Brizuela, B Malavaud, C Mazerolles, ... Current molecular pharmacology 3 (2), 53-65, 2010 | 80 | 2010 |
| Osteoblast-derived sphingosine 1-phosphate to induce proliferation and confer resistance to therapeutics to bone metastasis-derived prostate cancer cells L Brizuela, C Martin, P Jeannot, I Ader, C Gstalder, G Andrieu, M Bocquet, ... Molecular oncology 8 (7), 1181-1195, 2014 | 78 | 2014 |
| The radioprotective effect of the 24 kDa FGF-2 isoform in HeLa cells is related to an increased expression and activity of the DNA dependent protein kinase (DNA-PK) catalytic … I Ader, C Muller, J Bonnet, G Favre, E Cohen-Jonathan, B Salles, ... Oncogene 21 (42), 6471-6479, 2002 | 78 | 2002 |
| First evidence of sphingosine 1-phosphate lyase protein expression and activity downregulation in human neoplasm: implication for resistance to therapeutics in prostate cancer L Brizuela, I Ader, C Mazerolles, M Bocquet, B Malavaud, O Cuvillier Molecular cancer therapeutics 11 (9), 1841-1851, 2012 | 76 | 2012 |
| Inhibition of Rho pathways induces radiosensitization and oxygenation in human glioblastoma xenografts I Ader, C Delmas, J Bonnet, P Rochaix, G Favre, C Toulas, ... Oncogene 22 (55), 8861-8869, 2003 | 76 | 2003 |
| Essential role for SphK1/S1P signaling to regulate hypoxia-inducible factor 2α expression and activity in cancer P Bouquerel, C Gstalder, D Müller, J Laurent, L Brizuela, RA Sabbadini, ... Oncogenesis 5 (3), e209-e209, 2016 | 75 | 2016 |
| Gem associates with Ezrin and acts via the Rho-GAP protein Gmip to down-regulate the Rho pathway A Hatzoglou, I Ader, A Splingard, J Flanders, E Saade, I Leroy, S Traver, ... Molecular biology of the cell 18 (4), 1242-1252, 2007 | 74 | 2007 |
| Inhibition of the GTPase Rac1 mediates the antimigratory effects of metformin in prostate cancer cells B Dirat, I Ader, M Golzio, F Massa, A Mettouchi, K Laurent, F Larbret, ... Molecular cancer therapeutics 14 (2), 586-596, 2015 | 61 | 2015 |
| Farnesylated RhoB inhibits radiation-induced mitotic cell death and controls radiation-induced centrosome overduplication J Milia, F Teyssier, F Dalenc, I Ader, C Delmas, A Pradines, ... cell death and differentiation 12, 492-501, 2005 | 57 | 2005 |
| Synthesis, structures, and selective toxicity to cancer cells of gold (I) complexes involving N-heterocyclic carbene ligands L Boselli, I Ader, M Carraz, C Hemmert, O Cuvillier, H Gornitzka European journal of medicinal chemistry 85, 87-94, 2014 | 55 | 2014 |
| Increased expression of a COOH‐truncated nucleophosmin resulting from alternative splicing is associated with cellular resistance to ionizing radiation in HeLa cells F Dalenc, J Drouet, I Ader, C Delmas, P Rochaix, G Favre, ... International journal of cancer 100 (6), 662-668, 2002 | 54 | 2002 |
| FTY720 (Fingolimod) inhibits HIF1 and HIF2 signaling, promotes vascular remodeling, and chemosensitizes in renal cell carcinoma animal model C Gstalder, I Ader, O Cuvillier Molecular cancer therapeutics 15 (10), 2465-2474, 2016 | 53 | 2016 |
| Hypoxia, therapeutic resistance, and sphingosine 1-phosphate O Cuvillier, I Ader, P Bouquerel, L Brizuela, C Gstalder, B Malavaud Advances in cancer research 117, 117-141, 2013 | 46 | 2013 |
| The farnesyltransferase inhibitor FTI-277 suppresses the 24-kDa FGF2-induced radioresistance in HeLa cells expressing wild-type RAS E Cohen-Jonathan, C Toulas, I Ader, S Monteil, C Allal, J Bonnet, ... Radiation research 152 (4), 404-411, 1999 | 46 | 1999 |
