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James Brannigan
James Brannigan
York Structural Biology Laboratory
Verified email at york.ac.uk
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Cited by
Year
A protein catalytic framework with an N-terminal nucleophile is capable of self-activation
JA Brannigan, G Dodson, HJ Duggleby, PCE Moody, JL Smith, ...
Nature 378 (6555), 416-419, 1995
8231995
Crystal structure of a DExx box DNA helicase
HS Subramanya, LE Bird, JA Brannigan, DB Wigley
Nature 384 (6607), 379-383, 1996
5421996
Horizontal transfer of penicillin-binding protein genes in penicillin-resistant clinical isolates of Streptococcus pneumoniae.
CG Dowson, A Hutchison, JA Brannigan, RC George, D Hansman, ...
Proceedings of the National Academy of Sciences 86 (22), 8842-8846, 1989
5261989
N-myristoyltransferase inhibitors as new leads to treat sleeping sickness
JA Frearson, S Brand, SP McElroy, LAT Cleghorn, O Smid, L Stojanovski, ...
Nature 464 (7289), 728-732, 2010
3162010
Protein engineering 20 years on
JA Brannigan, AJ Wilkinson
Nature Reviews Molecular Cell Biology 3 (12), 964-970, 2002
2712002
Global profiling of co- and post-translationally N-myristoylated proteomes in human cells
E Thinon, RA Serwa, M Broncel, JA Brannigan, U Brassat, MH Wright, ...
Nature communications 5 (1), 4919, 2014
2432014
Recruitment of a penicillin-binding protein gene from Neisseria flavescens during the emergence of penicillin resistance in Neisseria meningitidis.
BG Spratt, QY Zhang, DM Jones, A Hutchison, JA Brannigan, CG Dowson
Proceedings of the National Academy of Sciences 86 (22), 8988-8992, 1989
2211989
Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach
MH Wright, B Clough, MD Rackham, K Rangachari, JA Brannigan, ...
Nature chemistry 6 (2), 112-121, 2014
2132014
Crystal structures of penicillin acylase enzyme-substrate complexes: structural insights into the catalytic mechanism
CE McVey, MA Walsh, GG Dodson, KS Wilson, JA Brannigan
Journal of molecular biology 313 (1), 139-150, 2001
1982001
Phosphorylated aspartate in the structure of a response regulator protein
RJ Lewis, JA Brannigan, K Muchová, I Barák, AJ Wilkinson
Journal of molecular biology 294 (1), 9-15, 1999
1921999
Structural and functional analysis of a conjugated bile salt hydrolase from Bifidobacterium longum reveals an evolutionary relationship with penicillin V acylase
RS Kumar, JA Brannigan, AA Prabhune, AV Pundle, GG Dodson, ...
Journal of Biological Chemistry 281 (43), 32516-32525, 2006
1612006
Pentapeptide regulation of aspartyl-phosphate phosphatases
M Perego, JA Brannigan
Peptides 22 (10), 1541-1547, 2001
1482001
Penicillin V acylase crystal structure reveals new Ntn-hydrolase family members
CG Suresh, AV Pundle, H SivaRaman, KN Rao, JA Brannigan, CE McVey, ...
Nature structural biology 6 (5), 414-416, 1999
1461999
Insertion of an extra amino acid is the main cause of the low affinity of penicillin‐binding protein 2 in penicillin‐resistant strains of Neisseria gonorrhoeae
JA Brannigan, IA Tirodimos, QY Zhang, CG Dowson, BG Spratt
Molecular microbiology 4 (6), 913-919, 1990
1311990
Ligand-induced conformational change in penicillin acylase
SH Done, JA Brannigan, PCE Moody, RE Hubbard
Journal of molecular biology 284 (2), 463-475, 1998
1251998
Crystal structure of GerE, the ultimate transcriptional regulator of spore formation in Bacillus subtilis
VMA Ducros, RJ Lewis, CS Verma, EJ Dodson, G Leonard, ...
Journal of Molecular Biology 306 (4), 759-771, 2001
1212001
Characterisation of Bacillus stearothermophilus PcrA helicase: Evidence against an active rolling mechanism
LE Bird, JA Brannigan, HS Subramanya, DB Wigley
Nucleic acids research 26 (11), 2686-2693, 1998
1211998
An evolutionary link between sporulation and prophage induction in the structure of a repressor: anti-repressor complex
RJ Lewis, JA Brannigan, WA Offen, I Smith, AJ Wilkinson
Journal of molecular biology 283 (5), 907-912, 1998
1201998
N-myristoyltransferase from Leishmania donovani: structural and functional characterisation of a potential drug target for visceral leishmaniasis
JA Brannigan, BA Smith, Z Yu, AM Brzozowski, MR Hodgkinson, A Maroof, ...
Journal of molecular biology 396 (4), 985-999, 2010
1182010
Water networks can determine the affinity of ligand binding to proteins
JF Darby, AP Hopkins, S Shimizu, SM Roberts, JA Brannigan, ...
Journal of the American Chemical Society 141 (40), 15818-15826, 2019
1072019
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