Richard Orton
Richard Orton
CVR Bioinformatics, MRC-University of Glasgow Centre for Virus Research
Verified email at - Homepage
Cited by
Cited by
Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway
RJ Orton, OE Sturm, V Vyshemirsky, M Calder, DR Gilbert, W Kolch
Biochemical Journal 392 (2), 249-261, 2005
Consensus statement: virus taxonomy in the age of metagenomics
P Simmonds, MJ Adams, M Benkő, M Breitbart, JR Brister, EB Carstens, ...
Nature Reviews Microbiology 15 (3), 161-168, 2017
Virus taxonomy: the database of the International Committee on Taxonomy of Viruses (ICTV)
EJ Lefkowitz, DM Dempsey, RC Hendrickson, RJ Orton, SG Siddell, ...
Nucleic acids research 46 (D1), D708-D717, 2018
Cell fate decisions are specified by the dynamic ERK interactome
A Von Kriegsheim, D Baiocchi, M Birtwistle, D Sumpton, W Bienvenut, ...
Nature cell biology 11 (12), 1458-1464, 2009
Late Ebola virus relapse causing meningoencephalitis: a case report
M Jacobs, A Rodger, DJ Bell, S Bhagani, I Cropley, A Filipe, RJ Gifford, ...
The Lancet 388 (10043), 498-503, 2016
The mammalian MAPK/ERK pathway exhibits properties of a negative feedback amplifier
OE Sturm, R Orton, J Grindlay, M Birtwistle, V Vyshemirsky, D Gilbert, ...
Science signaling 3 (153), ra90-ra90, 2010
Whole genome sequencing reveals local transmission patterns of Mycobacterium bovis in sympatric cattle and badger populations
R Biek, A O'Hare, D Wright, T Mallon, C McCormick, RJ Orton, ...
PLoS Pathog 8 (11), e1003008, 2012
Computational methodologies for modelling, analysis and simulation of signalling networks
D Gilbert, H Fuss, X Gu, R Orton, S Robinson, V Vyshemirsky, MJ Kurth, ...
Briefings in Bioinformatics 7 (4), 339-353, 2006
Analysis of signalling pathways using continuous time Markov chains
M Calder, V Vyshemirsky, D Gilbert, R Orton
Transactions on Computational Systems Biology VI, 44-67, 2006
Fundamental properties of the mammalian innate immune system revealed by multispecies comparison of type I interferon responses
AE Shaw, J Hughes, Q Gu, A Behdenna, JB Singer, T Dennis, RJ Orton, ...
PLoS biology 15 (12), e2004086, 2017
A structured approach for the engineering of biochemical network models, illustrated for signalling pathways
R Breitling, D Gilbert, M Heiner, R Orton
Briefings in bioinformatics 9 (5), 404-421, 2008
Analysis of signalling pathways using the PRISM model checker
M Calder, V Vyshemirsky, D Gilbert, R Orton
University of Edinburgh, 2005
Computational modelling of cancerous mutations in the EGFR/ERK signalling pathway
RJ Orton, ME Adriaens, A Gormand, OE Sturm, W Kolch, DR Gilbert
BMC systems biology 3 (1), 1-17, 2009
Risk factors for bovine tuberculosis at the national level in Great Britain
PR Bessell, R Orton, PCL White, MR Hutchings, RR Kao
BMC Veterinary Research 8 (1), 51, 2012
Predicting reservoir hosts and arthropod vectors from evolutionary signatures in RNA virus genomes
SA Babayan, RJ Orton, DG Streicker
Science 362 (6414), 577-580, 2018
50 years of the International Committee on Taxonomy of Viruses: progress and prospects
MJ Adams, EJ Lefkowitz, AMQ King, B Harrach, RL Harrison, NJ Knowles, ...
Archives of virology 162 (5), 1441-1446, 2017
Estimating epidemiological parameters for bovine tuberculosis in British cattle using a Bayesian partial-likelihood approach
A O'Hare, RJ Orton, PR Bessell, RR Kao
Proceedings of the Royal Society B: Biological Sciences 281 (1783), 20140248, 2014
Use of bacterial whole-genome sequencing to investigate local persistence and spread in bovine tuberculosis
H Trewby, D Wright, EL Breadon, SJ Lycett, TR Mallon, C McCormick, ...
Epidemics 14, 26-35, 2016
Distinguishing low frequency mutations from RT-PCR and sequence errors in viral deep sequencing data
RJ Orton, CF Wright, MJ Morelli, DJ King, DJ Paton, DP King, DT Haydon
BMC genomics 16 (1), 229, 2015
Next-generation sequencing in veterinary medicine: how can the massive amount of information arising from high-throughput technologies improve diagnosis, control, and†…
S Van Borm, S BelŠk, G Freimanis, A Fusaro, F Granberg, D HŲper, ...
Veterinary infection biology: molecular diagnostics and high-throughput†…, 2015
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