Hariharan Easwaran
Hariharan Easwaran
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Cancer epigenetics: tumor heterogeneity, plasticity of stem-like states, and drug resistance
H Easwaran, HC Tsai, SB Baylin
Molecular cell 54 (5), 716-727, 2014
Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands
HM O'Hagan, W Wang, S Sen, CDS Shields, SS Lee, YW Zhang, ...
Cancer cell 20 (5), 606-619, 2011
Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers
H Li, KB Chiappinelli, AA Guzzetta, H Easwaran, RWC Yen, R Vatapalli, ...
Oncotarget 5 (3), 587, 2014
Alterations of immune response of non-small cell lung cancer with azacytidine
J Wrangle, W Wang, A Koch, H Easwaran, HP Mohammad, F Vendetti, ...
Oncotarget 4 (11), 2067, 2013
A DNA hypermethylation module for the stem/progenitor cell signature of cancer
H Easwaran, SE Johnstone, L Van Neste, J Ohm, T Mosbruger, Q Wang, ...
Genome research 22 (5), 837-849, 2012
Proteogenomic characterization of pancreatic ductal adenocarcinoma
L Cao, C Huang, DC Zhou, Y Hu, TM Lih, SR Savage, K Krug, DJ Clark, ...
Cell 184 (19), 5031-5052. e26, 2021
Methyl CpG–binding proteins induce large-scale chromatin reorganization during terminal differentiation
A Brero, HP Easwaran, D Nowak, I Grunewald, T Cremer, H Leonhardt, ...
The Journal of cell biology 169 (5), 733-743, 2005
Epigenetic therapy inhibits metastases by disrupting premetastatic niches
Z Lu, J Zou, S Li, MJ Topper, Y Tao, H Zhang, X Jiao, W Xie, X Kong, ...
Nature 579 (7798), 284-290, 2020
Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer
W Zhang, SC Glöckner, M Guo, EO Machida, DH Wang, H Easwaran, ...
Cancer research 68 (8), 2764-2772, 2008
Replication‐independent chromatin loading of Dnmt1 during G2 and M phases
HP Easwaran, L Schermelleh, H Leonhardt, MC Cardoso
EMBO reports 5 (12), 1181-1186, 2004
Chronic cigarette smoke-induced epigenomic changes precede sensitization of bronchial epithelial cells to single-step transformation by KRAS mutations
M Vaz, SY Hwang, I Kagiampakis, J Phallen, A Patil, HM O'Hagan, ...
Cancer cell 32 (3), 360-376. e6, 2017
Prognostic value of CpG island methylator phenotype among colorectal cancer patients: a systematic review and meta-analysis
YY Juo, FM Johnston, DY Zhang, HH Juo, H Wang, EP Pappou, T Yu, ...
Annals of Oncology 25 (12), 2314-2327, 2014
Trapped in action: direct visualization of DNA methyltransferase activity in living cells
L Schermelleh, F Spada, HP Easwaran, K Zolghadr, JB Margot, ...
Nature methods 2 (10), 751-756, 2005
Abnormal DNA Methylation of CD133 in Colorectal and Glioblastoma Tumors
JM Yi, HC Tsai, SC Glöckner, S Lin, JE Ohm, H Easwaran, CD James, ...
Cancer research 68 (19), 8094-8103, 2008
Harnessing the potential of epigenetic therapy to target solid tumors
N Ahuja, H Easwaran, SB Baylin
The Journal of clinical investigation 124 (1), 56-63, 2014
MS-qFRET: a quantum dot-based method for analysis of DNA methylation
VJ Bailey, H Easwaran, Y Zhang, E Griffiths, SA Belinsky, JG Herman, ...
Genome research 19 (8), 1455-1461, 2009
Acetylation enhances TET2 function in protecting against abnormal DNA methylation during oxidative stress
YW Zhang, Z Wang, W Xie, Y Cai, L Xia, H Easwaran, J Luo, RWC Yen, ...
Molecular cell 65 (2), 323-335, 2017
Aging-like spontaneous epigenetic silencing facilitates Wnt activation, stemness, and BrafV600E-induced tumorigenesis
Y Tao, B Kang, DA Petkovich, YR Bhandari, J In, G Stein-O'Brien, X Kong, ...
Cancer cell 35 (2), 315-328. e6, 2019
DNMT1 modulates gene expression without its catalytic activity partially through its interactions with histone-modifying enzymes
EG Clements, HP Mohammad, BR Leadem, H Easwaran, Y Cai, ...
Nucleic acids research 40 (10), 4334-4346, 2012
Epigenetic regulation of gene expression in cancer: techniques, resources and analysis
LT Kagohara, GL Stein-O’Brien, D Kelley, E Flam, HC Wick, LV Danilova, ...
Briefings in functional genomics 17 (1), 49-63, 2018
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