| Cancer epigenetics: tumor heterogeneity, plasticity of stem-like states, and drug resistance H Easwaran, HC Tsai, SB Baylin Molecular cell 54 (5), 716-727, 2014 | 897 | 2014 |
| Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands HM O'Hagan, W Wang, S Sen, CDS Shields, SS Lee, YW Zhang, ... Cancer cell 20 (5), 606-619, 2011 | 524 | 2011 |
| Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers H Li, KB Chiappinelli, AA Guzzetta, H Easwaran, RWC Yen, R Vatapalli, ... Oncotarget 5 (3), 587, 2014 | 400 | 2014 |
| Alterations of immune response of non-small cell lung cancer with azacytidine J Wrangle, W Wang, A Koch, H Easwaran, HP Mohammad, F Vendetti, ... Oncotarget 4 (11), 2067, 2013 | 376 | 2013 |
| A DNA hypermethylation module for the stem/progenitor cell signature of cancer H Easwaran, SE Johnstone, L Van Neste, J Ohm, T Mosbruger, Q Wang, ... Genome research 22 (5), 837-849, 2012 | 273 | 2012 |
| Methyl CpG–binding proteins induce large-scale chromatin reorganization during terminal differentiation A Brero, HP Easwaran, D Nowak, I Grunewald, T Cremer, H Leonhardt, ... The Journal of cell biology 169 (5), 733-743, 2005 | 263 | 2005 |
| Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer W Zhang, SC Glockner, M Guo, EO Machida, DH Wang, H Easwaran, ... Cancer research 68 (8), 2764-2772, 2008 | 221 | 2008 |
| Epigenetic therapy inhibits metastases by disrupting premetastatic niches Z Lu, J Zou, S Li, MJ Topper, Y Tao, H Zhang, X Jiao, W Xie, X Kong, ... Nature 579 (7798), 284-290, 2020 | 202 | 2020 |
| Replication‐independent chromatin loading of Dnmt1 during G2 and M phases HP Easwaran, L Schermelleh, H Leonhardt, MC Cardoso EMBO reports 5 (12), 1181-1186, 2004 | 194 | 2004 |
| Prognostic value of CpG island methylator phenotype among colorectal cancer patients: a systematic review and meta-analysis YY Juo, FM Johnston, DY Zhang, HH Juo, H Wang, EP Pappou, T Yu, ... Annals of Oncology 25 (12), 2314-2327, 2014 | 168 | 2014 |
| Trapped in action: direct visualization of DNA methyltransferase activity in living cells L Schermelleh, F Spada, HP Easwaran, K Zolghadr, JB Margot, ... Nature methods 2 (10), 751-756, 2005 | 168 | 2005 |
| Abnormal DNA Methylation of CD133 in Colorectal and Glioblastoma Tumors JM Yi, HC Tsai, SC Glöckner, S Lin, JE Ohm, H Easwaran, CD James, ... Cancer research 68 (19), 8094-8103, 2008 | 164 | 2008 |
| Chronic Cigarette Smoke-Induced Epigenomic Changes Precede Sensitization of Bronchial Epithelial Cells to Single-Step Transformation by KRAS Mutations M Vaz, SY Hwang, I Kagiampakis, J Phallen, A Patil, HM O'Hagan, ... Cancer cell 32 (3), 360-376. e6, 2017 | 159 | 2017 |
| Harnessing the potential of epigenetic therapy to target solid tumors N Ahuja, H Easwaran, SB Baylin The Journal of clinical investigation 124 (1), 56-63, 2014 | 151 | 2014 |
| Proteogenomic characterization of pancreatic ductal adenocarcinoma L Cao, C Huang, DC Zhou, Y Hu, TM Lih, SR Savage, K Krug, DJ Clark, ... Cell 184 (19), 5031-5052. e26, 2021 | 149 | 2021 |
| MS-qFRET: a quantum dot-based method for analysis of DNA methylation VJ Bailey, H Easwaran, Y Zhang, E Griffiths, SA Belinsky, JG Herman, ... Genome research 19 (8), 1455-1461, 2009 | 145 | 2009 |
| Acetylation enhances TET2 function in protecting against abnormal DNA methylation during oxidative stress YW Zhang, Z Wang, W Xie, Y Cai, L Xia, H Easwaran, J Luo, RWC Yen, ... Molecular cell 65 (2), 323-335, 2017 | 124 | 2017 |
| DNMT1 modulates gene expression without its catalytic activity partially through its interactions with histone-modifying enzymes EG Clements, HP Mohammad, BR Leadem, H Easwaran, Y Cai, ... Nucleic acids research 40 (10), 4334-4346, 2012 | 124 | 2012 |
| Epigenetic regulation of gene expression in cancer: techniques, resources and analysis LT Kagohara, GL Stein-O’Brien, D Kelley, E Flam, HC Wick, LV Danilova, ... Briefings in functional genomics 17 (1), 49-63, 2018 | 109 | 2018 |
| Aging-like spontaneous epigenetic silencing facilitates Wnt activation, stemness, and BrafV600E-induced tumorigenesis Y Tao, B Kang, DA Petkovich, YR Bhandari, J In, G Stein-O'Brien, X Kong, ... Cancer cell 35 (2), 315-328. e6, 2019 | 104 | 2019 |
Stephen B. BaylinJohns Hopkins University, Van Andel Research InstituteVerified email at vai.org
