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Mohammad A. Ghattas
Mohammad A. Ghattas
Professor of Medicinal Chemistry & Drug Design, Al Ain University of Science and Technology
Verified email at aau.ac.ae - Homepage
Title
Cited by
Cited by
Year
Anti-inflammatory drug approach: synthesis and biological evaluation of novel pyrazolo [3, 4-d] pyrimidine compounds
N Atatreh, AM Youssef, MA Ghattas, M Al Sorkhy, S Alrawashdeh, ...
Bioorganic chemistry 86, 393-400, 2019
452019
Discovery of new butyrylcholinesterase inhibitors via structure-based virtual screening
N Atatreh, S Al Rawashdah, SS Al Neyadi, SM Abuhamdah, MA Ghattas
Journal of Enzyme Inhibition and Medicinal Chemistry 34 (1), 1373-1379, 2019
402019
Druggability analysis and classification of protein tyrosine phosphatase active sites
MA Ghattas, N Raslan, A Sadeq, M Al Sorkhy, N Atatreh
Drug design, development and therapy, 3197-3209, 2016
392016
Antibacterial activity and mechanism of action of the benzazole acrylonitrile-based compounds: In vitro, spectroscopic, and docking studies
SS AlNeyadi, AA Salem, MA Ghattas, N Atatreh, IM Abdou
European Journal of Medicinal Chemistry 136, 270-282, 2017
382017
Identification of new inhibitors of Mdm2–p53 interaction via pharmacophore and structure-based virtual screening
N Atatreh, MA Ghattas, SK Bardaweel, SA Rawashdeh, MA Sorkhy
Drug design, development and therapy, 3741-3752, 2018
352018
Characterization of human serum albumin's interactions with safranal and crocin using multi-spectroscopic and molecular docking techniques
AA Salem, M Lotfy, A Amin, MA Ghattas
Biochemistry and biophysics reports 20, 100670, 2019
342019
Src family kinase inhibitor Saracatinib (AZD0530) impairs oxaliplatin uptake in colorectal cancer cells and blocks organic cation transporters
CJ Morrow, M Ghattas, C Smith, H Bönisch, RA Bryce, DM Hickinson, ...
Cancer research 70 (14), 5931-5941, 2010
282010
Allosteric binding sites of the SARS-CoV-2 main protease: potential targets for broad-spectrum anti-coronavirus agents
L Alzyoud, MA Ghattas, N Atatreh
Drug Design, Development and Therapy 16, 2463, 2022
202022
Effects of antihistamines on the function of human α7-nicotinic acetylcholine receptors
B Sadek, SS Khanian, A Ashoor, T Prytkova, MA Ghattas, N Atatreh, ...
European journal of pharmacology 746, 308-316, 2015
202015
Glucosamine enhances paracetamol bioavailability by reducing its metabolism
NA Qinna, MH Shubbar, KZ Matalka, N Al-Jbour, MA Ghattas, AA Badwan
Journal of pharmaceutical sciences 104 (1), 257-265, 2015
202015
A de novo mutation in the X-linked PAK3 gene is the underlying cause of intellectual disability and macrocephaly in monozygotic twins
J Hertecant, M Komara, A Nagi, O Al-Zaabi, W Fathallah, H Cui, Y Yang, ...
European Journal of Medical Genetics 60 (4), 212-216, 2017
182017
Anti-cancer activity and molecular docking of some pyrano [3, 2‑c] quinoline analogues
AM Saeed, IM Abdou, AA Salem, MA Ghattas, N Atatreh, SS AlNeyadi
Open Journal of Medicinal Chemistry 10 (1), 1-14, 2020
152020
Analysis of Enoyl‐Acyl carrier protein reductase structure and interactions yields an efficient virtual screening approach and suggests a potential allosteric site
MA Ghattas, RA Mansour, N Atatreh, RA Bryce
Chemical biology & drug design 87 (1), 131-142, 2016
152016
How do small molecule aggregates inhibit enzyme activity? A molecular dynamics study
MA Ghattas, S Al Rawashdeh, N Atatreh, RA Bryce
Journal of Chemical Information and Modeling 60 (8), 3901-3909, 2020
142020
Design, synthesis, in vitro antibacterial activity, and docking studies of new rhodanine derivatives
A Abusetta, J Alumairi, MY Alkaabi, R Al Ajeil, AA Shkaidim, D Akram, ...
Open Journal of Medicinal Chemistry 10 (1), 15-34, 2020
142020
Structure-based assessment and druggability classification of protein–protein interaction sites
L Alzyoud, RA Bryce, M Al Sorkhy, N Atatreh, MA Ghattas
Scientific Reports 12 (1), 7975, 2022
132022
Using filters in virtual screening: A comprehensive guide to minimize errors and maximize efficiency
RE Mahgoub, N Atatreh, MA Ghattas
Annual Reports in Medicinal Chemistry 59, 99-136, 2022
132022
Protein tyrosine phosphatases: Ligand interaction analysis and optimisation of virtual screening
MA Ghattas, N Atatreh, EV Bichenkova, RA Bryce
Journal of Molecular Graphics and Modelling 52, 114-123, 2014
132014
Controlled release of pyrimidine compound using polymeric coated ZIF-8 metal-organic framework as glucagon-like peptide-1 receptor agonist carrier
SS AlNeyadi, N Amir, MA Ghattas, N Atatreh, SS Alketbi, RA Ajeil, A Adem
Molecules 25 (18), 4313, 2020
112020
Non-selective inhibition of cyclooxygenase enzymes by aminoacetylenic isoindoline 1, 3-diones
N A Qinna, Z A Muhi-eldeen, M Ghattas, T M Alhussainy, J Al-Qaisi, ...
Inflammation & Allergy-Drug Targets (Formerly Current Drug Targets …, 2012
112012
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