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Genome engineering using the CRISPR-Cas9 system F Ran, PD Hsu, J Wright, V Agarwala, DA Scott, F Zhang Nature protocols 8 (11), 2281-2308, 2013 | 12524 | 2013 |
Development and applications of CRISPR-Cas9 for genome engineering PD Hsu, ES Lander, F Zhang Cell 157 (6), 1262-1278, 2014 | 6935 | 2014 |
DNA targeting specificity of RNA-guided Cas9 nucleases PD Hsu, DA Scott, JA Weinstein, FA Ran, S Konermann, V Agarwala, Y Li, ... Nature biotechnology 31 (9), 827-832, 2013 | 5610 | 2013 |
Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity FA Ran, PD Hsu, CY Lin, JS Gootenberg, S Konermann, AE Trevino, ... Cell 154 (6), 1380-1389, 2013 | 4332 | 2013 |
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex S Konermann, MD Brigham, AE Trevino, J Joung, OO Abudayyeh, ... Nature 517 (7536), 583-588, 2015 | 3065 | 2015 |
Crystal structure of Cas9 in complex with guide RNA and target DNA H Nishimasu, FA Ran, PD Hsu, S Konermann, SI Shehata, N Dohmae, ... Cell 156 (5), 935-949, 2014 | 2467 | 2014 |
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells X Wu, DA Scott, AJ Kriz, AC Chiu, PD Hsu, DB Dadon, AW Cheng, ... Nature biotechnology 32 (7), 670-676, 2014 | 1192 | 2014 |
Optical control of mammalian endogenous transcription and epigenetic states S Konermann, MD Brigham, AE Trevino, PD Hsu, M Heidenreich, L Cong, ... Nature 500 (7463), 472-476, 2013 | 1085 | 2013 |
Transcriptome engineering with RNA-targeting type VI-D CRISPR effectors S Konermann, P Lotfy, NJ Brideau, J Oki, MN Shokhirev, PD Hsu Cell 173 (3), 665-676. e14, 2018 | 1082 | 2018 |
Engineering of systems, methods and optimized guide compositions for sequence manipulation F Zhang, L Cong, P Hsu, RAN Fei US Patent 8,906,616, 2014 | 600* | 2014 |
Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus W Yang, N Shen, DQ Ye, Q Liu, Y Zhang, XX Qian, N Hirankarn, D Ying, ... PLoS genetics 6 (2), e1000841, 2010 | 462 | 2010 |
Structure and engineering of Francisella novicida Cas9 H Hirano, JS Gootenberg, T Horii, OO Abudayyeh, M Kimura, PD Hsu, ... Cell 164 (5), 950-961, 2016 | 404 | 2016 |
Methods for optimizing CRISPR-Cas9 genome editing specificity J Tycko, VE Myer, PD Hsu Molecular cell 63 (3), 355-370, 2016 | 361 | 2016 |
Crispr-cas component systems, methods and compositions for sequence manipulation F Zhang, L Cong, DBT Cox, P Hsu, LIN Shuailiang, RAN Fei, RJ Platt, ... US Patent App. 14/105,035, 2014 | 302 | 2014 |
Test performance evaluation of SARS-CoV-2 serological assays JD Whitman, J Hiatt, CT Mowery, BR Shy, R Yu, TN Yamamoto, U Rathore, ... Nature biotechnology 38 (10), 1174, 2020 | 269 | 2020 |
Evaluation of SARS-CoV-2 serology assays reveals a range of test performance JD Whitman, J Hiatt, CT Mowery, BR Shy, R Yu, TN Yamamoto, U Rathore, ... Nature biotechnology 38 (10), 1174-1183, 2020 | 256 | 2020 |
Delivery and specificity of CRISPR/Cas9 genome editing technologies for human gene therapy JL Gori, PD Hsu, ML Maeder, S Shen, GG Welstead, D Bumcrot Human gene therapy 26 (7), 443-451, 2015 | 256 | 2015 |
Structural basis for the RNA-guided ribonuclease activity of CRISPR-Cas13d C Zhang, S Konermann, NJ Brideau, P Lotfy, X Wu, SJ Novick, ... Cell 175 (1), 212-223. e17, 2018 | 251 | 2018 |
CRISPR-Cas component systems, methods and compositions for sequence manipulation F Zhang, DO BIKARD, L Cong, DBT Cox, P Hsu, W Jiang, LIN Shauiliang, ... | 231 | 2015 |