Microscale bioprocess optimisation M Micheletti, GJ Lye Current opinion in biotechnology 17 (6), 611-618, 2006 | 199 | 2006 |
Fluid mixing in shaken bioreactors: Implications for scale-up predictions from microlitre-scale microbial and mammalian cell cultures M Micheletti, T Barrett, SD Doig, F Baganz, MS Levy, JM Woodley, GJ Lye Chemical Engineering Science 61 (9), 2939-2949, 2006 | 165 | 2006 |
A multidisciplinary approach toward the rapid and preparative-scale biocatalytic synthesis of chiral amino alcohols: a concise transketolase-/ω-transaminase-mediated synthesis … MEB Smith, BH Chen, EG Hibbert, U Kaulmann, K Smithies, JL Galman, ... Organic Process Research & Development 14 (1), 99-107, 2010 | 104 | 2010 |
Particle concentration and mixing characteristics of moderate-to-dense solid− liquid suspensions M Micheletti, L Nikiforaki, KC Lee, M Yianneskis Industrial & engineering chemistry research 42 (24), 6236-6249, 2003 | 104 | 2003 |
On the fluid dynamics of a laboratory scale single-use stirred bioreactor AOO Odeleye, DTJ Marsh, MD Osborne, GJ Lye, M Micheletti Chemical engineering science 111, 299-312, 2014 | 71 | 2014 |
On the measurement and scaling of mixing time in orbitally shaken bioreactors G Rodriguez, T Anderlei, M Micheletti, M Yianneskis, A Ducci Biochemical engineering journal 82, 10-21, 2014 | 66 | 2014 |
On spatial and temporal variations and estimates of energy dissipation in stirred reactors M Micheletti, S Baldi, SL Yeoh, A Ducci, G Papadakis, KC Lee, ... Chemical Engineering Research and Design 82 (9), 1188-1198, 2004 | 65 | 2004 |
Mixing time and kinetic energy measurements in a shaken cylindrical bioreactor G Rodriguez, W Weheliye, T Anderlei, M Micheletti, M Yianneskis, A Ducci Chemical Engineering Research and Design 91 (11), 2084-2097, 2013 | 63 | 2013 |
How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology? MJT Carrondo, PM Alves, N Carinhas, J Glassey, F Hesse, OW Merten, ... Biotechnology Journal 7 (12), 1522-1529, 2012 | 52 | 2012 |
Microscale process evaluation of recombinant biocatalyst libraries: application to Baeyer–Villiger monooxygenase catalysed lactone synthesis C Ferreira-Torres, M Micheletti, GJ Lye Bioprocess and biosystems engineering 28, 83-93, 2005 | 50 | 2005 |
α, α'-dihydroxy ketones and 2-amino-1, 3-diols: synthetic and process strategies using biocatalysts H C Hailes, P A Dalby, G J Lye, F Baganz, M Micheletti, N Szita, J M Ward Current Organic Chemistry 14 (17), 1883-1893, 2010 | 44 | 2010 |
Hydrodynamic and oxygen mass transfer studies in a three-phase (air–water–ionic liquid) stirred tank bioreactor D Torres-Martínez, R Melgarejo-Torres, M Gutiérrez-Rojas, ... Biochemical engineering journal 45 (3), 209-217, 2009 | 43 | 2009 |
Study of fluid velocity characteristics in stirred solid-liquid suspensions with a refractive index matching technique M Micheletti, M Yianneskis Proceedings of the Institution of Mechanical Engineers, Part E: Journal of …, 2004 | 35 | 2004 |
Establishing the scalable manufacture of primary human T‐cells in an automated stirred‐tank bioreactor E Costariol, M Rotondi, A Amini, CJ Hewitt, AW Nienow, TRJ Heathman, ... Biotechnology and bioengineering 116 (10), 2488-2502, 2019 | 30 | 2019 |
Microscale methods to rapidly evaluate bioprocess options for increasing bioconversion yields: application to the ω-transaminase synthesis of chiral amines M Halim, L Rios-Solis, M Micheletti, JM Ward, GJ Lye Bioprocess and biosystems engineering 37, 931-941, 2014 | 27 | 2014 |
Transformation of biopharmaceutical manufacturing through single-use technologies: Current state, remaining challenges, and future development JJ Samaras, M Micheletti, W Ding Annual Review of Chemical and Biomolecular Engineering 13, 73-97, 2022 | 23 | 2022 |
Mode decomposition and Lagrangian structures of the flow dynamics in orbitally shaken bioreactors WH Weheliye, N Cagney, G Rodriguez, M Micheletti, A Ducci Physics of Fluids 30 (3), 2018 | 21 | 2018 |
An efficient approach to bioconversion kinetic model generation based on automated microscale experimentation integrated with model driven experimental design BH Chen, M Micheletti, F Baganz, JM Woodley, GJ Lye Chemical engineering science 64 (2), 403-409, 2009 | 21 | 2009 |
An automated microscale platform for evaluation and optimization of oxidative bioconversion processes JZ Baboo, JL Galman, GJ Lye, JM Ward, HC Hailes, M Micheletti Biotechnology progress 28 (2), 392-405, 2012 | 19 | 2012 |
Characterisation of osteogenic and vascular responses of hMSCs to Ti-Co doped phosphate glass microspheres using a microfluidic perfusion platform C Peticone, DDS Thompson, N Dimov, B Jevans, N Glass, M Micheletti, ... Journal of tissue engineering 11, 2041731420954712, 2020 | 18 | 2020 |