Huong Le
Huong Le
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Multivariate analysis of cell culture bioprocess data—lactate consumption as process indicator
H Le, S Kabbur, L Pollastrini, Z Sun, K Mills, K Johnson, G Karypis, WS Hu
Journal of biotechnology 162 (2-3), 210-223, 2012
Mining manufacturing data for discovery of high productivity process characteristics
S Charaniya, H Le, H Rangwala, K Mills, K Johnson, G Karypis, WS Hu
Journal of biotechnology 147 (3-4), 186-197, 2010
Global insights into the Chinese hamster and CHO cell transcriptomes
N Vishwanathan, A Yongky, KC Johnson, HY Fu, NM Jacob, H Le, ...
Biotechnology and bioengineering 112 (5), 965-976, 2015
Dynamic gene expression for metabolic engineering of mammalian cells in culture
H Le, N Vishwanathan, A Kantardjieff, I Doo, M Srienc, X Zheng, N Somia, ...
Metabolic engineering 20, 212-220, 2013
Cell line development for biomanufacturing processes: recent advances and an outlook
H Le, N Vishwanathan, NM Jacob, M Gadgil, WS Hu
Biotechnology letters 37, 1553-1564, 2015
Human germline heterozygous gain-of-function STAT6 variants cause severe allergic disease
M Sharma, D Leung, M Momenilandi, LCW Jones, L Pacillo, AE James, ...
Journal of Experimental Medicine 220 (5), e20221755, 2023
Transcriptome dynamics of transgene amplification in Chinese hamster ovary cells
N Vishwanathan, H Le, NM Jacob, YS Tsao, SW Ng, B Loo, Z Liu, ...
Biotechnology and bioengineering 111 (3), 518-528, 2014
Advancing biopharmaceutical process science through transcriptome analysis
N Vishwanathan, H Le, T Le, WS Hu
Current opinion in biotechnology 30, 113-119, 2014
Assuring clonality on the beacon digital cell line development platform
K Le, C Tan, H Le, J Tat, E Zasadzinska, J Diep, R Zastrow, C Chen, ...
Biotechnology Journal 15 (1), 1900247, 2020
Accelerating patient access to novel biologics using stable pool‐derived product for non‐clinical studies and single clone‐derived product for clinical studies
TP Munro, K Le, H Le, L Zhang, J Stevens, N Soice, SA Benchaar, ...
Biotechnology Progress 33 (6), 1476-1482, 2017
Integration of systems biology in cell line and process development for biopharmaceutical manufacturing
C Chen, H Le, CT Goudar
Biochemical Engineering Journal 107, 11-17, 2016
An automated RNA‐Seq analysis pipeline to identify and visualize differentially expressed genes and pathways in CHO cells
C Chen, H Le, CT Goudar
Biotechnology Progress 31 (5), 1150-1162, 2015
Evaluation of two public genome references for chinese hamster ovary cells in the context of rna‐seq based gene expression analysis
C Chen, H Le, CT Goudar
Biotechnology and Bioengineering 114 (7), 1603-1613, 2017
Augmenting Chinese hamster genome assembly by identifying regions of high confidence
N Vishwanathan, AA Bandyopadhyay, HY Fu, M Sharma, KC Johnson, ...
Biotechnology Journal 11 (9), 1151-1157, 2016
An evaluation of public genomic references for mapping RNA‐Seq data from Chinese hamster ovary cells
H Le, C Chen, CT Goudar
Biotechnology and Bioengineering 112 (11), 2412-2416, 2015
From chemostats to high‐density perfusion: the progression of continuous mammalian cell cultivation
HE Wong, C Chen, H Le, CT Goudar
Journal of Chemical Technology & Biotechnology 97 (9), 2297-2304, 2022
Methods for estimating the probability of clonality in cell line development
C Chen, K Le, H Le, K Daris, N Soice, J Stevens, CT Goudar
Biotechnology Journal 15 (2), 1900289, 2020
Continuous processing in upstream operations
H Le, H Chen, CT Goudar
Chemical engineering progress 111 (12), 32-37, 2015
Microfluidic chip‐based single‐cell cloning to accelerate biologic production timelines
J Diep, H Le, K Le, E Zasadzinska, J Tat, P Yam, R Zastrow, N Gomez, ...
Biotechnology Progress 37 (6), e3192, 2021
Transcriptome data analysis for cell culture processes
M Castro-Melchor, H Le, WS Hu
Genomics and Systems Biology of Mammalian Cell Culture, 27-70, 2012
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