متابعة
gustavo leone
gustavo leone
Professor of Biochemistry, medical college of wisconsin
بريد إلكتروني تم التحقق منه على mcw.edu
عنوان
عدد مرات الاقتباسات
عدد مرات الاقتباسات
السنة
Emerging roles of E2Fs in cancer: an exit from cell cycle control
HZ Chen, SY Tsai, G Leone
Nature reviews cancer 9 (11), 785-797, 2009
10652009
Distinct roles for E2F proteins in cell growth control and apoptosis
J DeGregori, G Leone, A Miron, L Jakoi, JR Nevins
Proceedings of the National Academy of Sciences 94 (14), 7245-7250, 1997
9141997
The E2F1–3 transcription factors are essential for cellular proliferation
L Wu, C Timmers, B Maiti, HI Saavedra, L Sang, GT Chong, F Nuckolls, ...
Nature 414 (6862), 457-462, 2001
7612001
Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis
S Ishida, E Huang, H Zuzan, R Spang, G Leone, M West, JR Nevins
Molecular and cellular biology 21 (14), 4684-4699, 2001
7272001
Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F
G Leone, J DeGregori, R Sears, L Jakoi, JR Nevins
Nature 387 (6631), 422-426, 1997
6281997
Pten in stromal fibroblasts suppresses mammary epithelial tumours
AJ Trimboli, CZ Cantemir-Stone, F Li, JA Wallace, A Merchant, N Creasap, ...
Nature 461 (7267), 1084-1091, 2009
6052009
The broken cycle: E2F dysfunction in cancer
LN Kent, G Leone
Nature Reviews Cancer 19 (6), 326-338, 2019
5792019
Ras enhances Myc protein stability
R Sears, G Leone, J DeGregori, JR Nevins
Molecular cell 3 (2), 169-179, 1999
5631999
Direct evidence for epithelial-mesenchymal transitions in breast cancer
AJ Trimboli, K Fukino, A De Bruin, G Wei, L Shen, SM Tanner, N Creasap, ...
Cancer research 68 (3), 937-945, 2008
4842008
E2F3 activity is regulated during the cell cycle and is required for the induction of S phase
G Leone, J DeGregori, Z Yan, L Jakoi, S Ishida, RS Williams, JR Nevins
Genes & development 12 (14), 2120-2130, 1998
4671998
Extra-embryonic function of Rb is essential for embryonic development and viability
L Wu, A De Bruin, HI Saavedra, M Starovic, A Trimboli, Y Yang, J Opavska, ...
Nature 421 (6926), 942-947, 2003
4432003
Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320
A Bronisz, J Godlewski, JA Wallace, AS Merchant, MO Nowicki, ...
Nature cell biology 14 (2), 159-167, 2012
3282012
Myc requires distinct E2F activities to induce S phase and apoptosis
G Leone, R Sears, E Huang, R Rempel, F Nuckolls, CH Park, ...
Molecular cell 8 (1), 105-113, 2001
3252001
The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state
EJ Smith, G Leone, J DeGregori, L Jakoi, JR Nevins
Molecular and cellular biology, 1996
3231996
Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells
Z Yan, J DeGregori, R Shohet, G Leone, B Stillman, JR Nevins, ...
Proceedings of the National Academy of Sciences 95 (7), 3603-3608, 1998
3191998
Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation
A De Bruin, B Maiti, L Jakoi, C Timmers, R Buerki, G Leone
Journal of Biological Chemistry 278 (43), 42041-42049, 2003
3102003
E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity.
J DeGregori, G Leone, K Ohtani, A Miron, JR Nevins
Genes & development 9 (23), 2873-2887, 1995
2931995
E2f1–3 switch from activators in progenitor cells to repressors in differentiating cells
JL Chong, PL Wenzel, MT Sáenz-Robles, V Nair, A Ferrey, JP Hagan, ...
Nature 462 (7275), 930-934, 2009
2822009
Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer
Z Qamri, A Preet, MW Nasser, CE Bass, G Leone, SH Barsky, RK Ganju
Molecular cancer therapeutics 8 (11), 3117-3129, 2009
2712009
Role of the Rb/E2F pathway in cell growth control
JR Nevins, G Leone, J DeGregori, L Jakoi
Journal of cellular physiology 173 (2), 233-236, 1997
2691997
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مقالات 1–20