| The Hsp70 chaperone network. R Rosenzweig, NB Nillegoda, MP Mayer, B Bukau Nature Reviews Molecular Cell Biology, 2019 | 907 | 2019 |
| Human Hsp70 disaggregase reverses Parkinson’s-linked α-synuclein amyloid fibrils X Gao, M Carroni, C Nussbaum-Krammer, A Mogk, NB Nillegoda, ... Molecular cell 59 (5), 781-793, 2015 | 390 | 2015 |
| Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation NB Nillegoda, J Kirstein, A Szlachcic, M Berynskyy, A Stank, F Stengel, ... Nature 524 (7564), 247-251, 2015 | 359 | 2015 |
| Metazoan Hsp70 machines use Hsp110 to power protein disaggregation H Rampelt, J Kirstein‐Miles, NB Nillegoda, K Chi, SR Scholz, RI Morimoto, ... The EMBO journal 31 (21), 4221-4235, 2012 | 341 | 2012 |
| A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins J Jones, K Wu, Y Yang, C Guerrero, N Nillegoda, ZQ Pan, L Huang Journal of proteome research 7 (3), 1274-1287, 2008 | 192 | 2008 |
| Molecular dissection of amyloid disaggregation by human HSP70 AS Wentink, NB Nillegoda, J Feufel, G Ubartaitė, CP Schneider, ... Nature 587 (7834), 483-488, 2020 | 175 | 2020 |
| Ubr1 and Ubr2 function in a quality control pathway for degradation of unfolded cytosolic proteins NB Nillegoda, MA Theodoraki, AK Mandal, KJ Mayo, HY Ren, R Sultana, ... Molecular biology of the cell 21 (13), 2102-2116, 2010 | 169 | 2010 |
| HSP40 proteins use class-specific regulation to drive HSP70 functional diversity O Faust, M Abayev-Avraham, AS Wentink, M Maurer, NB Nillegoda, ... Nature 587 (7834), 489-494, 2020 | 152 | 2020 |
| Hsp70 displaces small heat shock proteins from aggregates to initiate protein refolding S Zwirowski, A Kłosowska, I Obuchowski, NB Nillegoda, A Piróg, ... The EMBO Journal 36 (6), 783-796, 2017 | 150 | 2017 |
| Function, evolution, and structure of J-domain proteins HH Kampinga, C Andreasson, A Barducci, ME Cheetham, D Cyr, ... Cell Stress and Chaperones 24, 7-15, 2019 | 142 | 2019 |
| Metazoan Hsp70-based protein disaggregases: emergence and mechanisms NB Nillegoda, B Bukau Frontiers in molecular biosciences 2, 57, 2015 | 130 | 2015 |
| Protein Disaggregation in Multicellular Organisms NB Nillegoda, AS Wentink, B Bukau Trends in Biochemical Sciences, doi.org/10.1016/j.tibs.2018.02.003, 2018 | 123 | 2018 |
| Cdc37 has distinct roles in protein kinase quality control that protect nascent chains from degradation and promote posttranslational maturation AK Mandal, P Lee, JA Chen, N Nillegoda, A Heller, S DiStasio, H Oen, ... Journal of Cell Biology 176 (3), 319-328, 2007 | 121 | 2007 |
| A network of ubiquitin ligases is important for the dynamics of misfolded protein aggregates in yeast MA Theodoraki, NB Nillegoda, J Saini, AJ Caplan Journal of Biological Chemistry 287 (28), 23911-23922, 2012 | 78 | 2012 |
| Evolution of an intricate J-protein network driving protein disaggregation in eukaryotes NB Nillegoda, A Stank, D Malinverni, N Alberts, A Szlachcic, A Barducci, ... eLIFE 6 (e24560), e24560, 2017 | 76 | 2017 |
| Hsp110 chaperones control client fate determination in the Hsp70–Hsp90 chaperone system AK Mandal, PA Gibney, NB Nillegoda, MA Theodoraki, AJ Caplan, ... Molecular biology of the cell 21 (9), 1439-1448, 2010 | 69 | 2010 |
| In vivo properties of the disaggregase function of J-proteins and Hsc70 in C. elegans stress and aging J Kirstein, K Arnsburg, A Scior, A Szlachcic, DL Guilbride, RI Morimoto, ... Aging Cell 16 (6), 1414-1424, 2017 | 64 | 2017 |
| Functional diversity between HSP70 paralogs caused by variable interactions with specific co-chaperones D Serlidaki, MAWH van Waarde, L Rohland, AS Wentink, SL Dekker, ... Journal of Biological Chemistry 295 (21), 7301-7316, 2020 | 51 | 2020 |
| Substrate binding by the yeast Hsp110 nucleotide exchange factor and molecular chaperone, Sse1, is not obligate for its biological activities VM Garcia, NB Nillegoda, B Bukau, KA Morano Molecular Biology of the Cell 28 (15), 2066-2075, 2017 | 39 | 2017 |
| Ydj1 protects nascent protein kinases from degradation and controls the rate of their maturation AK Mandal, NB Nillegoda, JA Chen, AJ Caplan Molecular and cellular biology 28 (13), 4434-4444, 2008 | 38 | 2008 |
Avrom J. CaplanPace UniversityVerified email at pace.edu
