| The expanding universe of p53 targets D Menendez, A Inga, MA Resnick Nature reviews Cancer 9 (10), 724-737, 2009 | 633 | 2009 |
| A highly specific SpCas9 variant is identified by in vivo screening in yeast A Casini, M Olivieri, G Petris, C Montagna, G Reginato, G Maule, ... Nature biotechnology 36 (3), 265-271, 2018 | 307 | 2018 |
| Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence A Inga, F Storici, TA Darden, MA Resnick Molecular and cellular biology 22 (24), 8612-8625, 2002 | 214 | 2002 |
| The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis B Leroy, JL Fournier, C Ishioka, P Monti, A Inga, G Fronza, T Soussi Nucleic acids research 41 (D1), D962-D969, 2013 | 178 | 2013 |
| Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity MA Resnick, A Inga Proceedings of the National Academy of Sciences 100 (17), 9934-9939, 2003 | 173 | 2003 |
| p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements P Campomenosi, P Monti, A Aprile, A Abbondandolo, T Frebourg, B Gold, ... Oncogene 20 (27), 3573-3579, 2001 | 163 | 2001 |
| Noncanonical DNA motifs as transactivation targets by wild type and mutant p53 JJ Jordan, D Menendez, A Inga, M Nourredine, D Bell, MA Resnick PLoS genetics 4 (6), e1000104, 2008 | 125 | 2008 |
| The ribonucleic complex HuR-MALAT1 represses CD133 expression and suppresses epithelial–mesenchymal transition in breast cancer E Latorre, S Carelli, I Raimondi, V D'Agostino, I Castiglioni, C Zucal, ... Cancer research 76 (9), 2626-2636, 2016 | 104 | 2016 |
| A loss-of-function mutation in the binding domain of HAND1 predicts hypoplasia of the human hearts SM Reamon-Buettner, Y Ciribilli, A Inga, J Borlak Human molecular genetics 17 (10), 1397-1405, 2008 | 104 | 2008 |
| Conserved pseudoknots in lncRNA MEG3 are essential for stimulation of the p53 pathway T Uroda, E Anastasakou, A Rossi, JM Teulon, JL Pellequer, P Annibale, ... Molecular cell 75 (5), 982-995. e9, 2019 | 98 | 2019 |
| The biological impact of the human master regulator p53 can be altered by mutations that change the spectrum and expression of its target genes D Menendez, A Inga, MA Resnick Molecular and cellular biology 26 (6), 2297-2308, 2006 | 95 | 2006 |
| More targets, more pathways and more clues for mutant p53 S Garritano, A Inga, F Gemignani, S Landi Oncogenesis 2 (7), e54-e54, 2013 | 90 | 2013 |
| Functionally distinct polymorphic sequences in the human genome that are targets for p53 transactivation DJ Tomso, A Inga, D Menendez, GS Pittman, MR Campbell, F Storici, ... Proceedings of the National Academy of Sciences 102 (18), 6431-6436, 2005 | 88 | 2005 |
| A SNP in the flt-1 promoter integrates the VEGF system into the p53 transcriptional network D Menendez, O Krysiak, A Inga, B Krysiak, MA Resnick, G Schönfelder Proceedings of the National Academy of Sciences 103 (5), 1406-1411, 2006 | 86 | 2006 |
| Identification of a core TP53 transcriptional program with highly distributed tumor suppressive activity Z Andrysik, MD Galbraith, AL Guarnieri, S Zaccara, KD Sullivan, A Pandey, ... Genome research 27 (10), 1645-1657, 2017 | 85 | 2017 |
| Functional evolution of the p53 regulatory network through its target response elements AG Jegga, A Inga, D Menendez, BJ Aronow, MA Resnick Proceedings of the National Academy of Sciences 105 (3), 944-949, 2008 | 77 | 2008 |
| Tumour p53 mutations exhibit promoter selective dominance over wild type p53 P Monti, P Campomenosi, Y Ciribilli, R Iannone, A Inga, A Abbondandolo, ... Oncogene 21 (11), 1641-1648, 2002 | 75 | 2002 |
| Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes P Monti, C Perfumo, A Bisio, Y Ciribilli, P Menichini, D Russo, ... Molecular Cancer Research 9 (3), 271-279, 2011 | 71 | 2011 |
| A functional genetic study identifies HAND1 mutations in septation defects of the human heart SM Reamon-Buettner, Y Ciribilli, I Traverso, B Kuhls, A Inga, J Borlak Human molecular genetics 18 (19), 3567-3578, 2009 | 70 | 2009 |
| Altered-function p53 missense mutations identified in breast cancers can have subtle effects on transactivation JJ Jordan, A Inga, K Conway, S Edmiston, LA Carey, L Wu, MA Resnick Molecular cancer research 8 (5), 701-716, 2010 | 68 | 2010 |
