| Nrf2-deficient female mice develop lupus-like autoimmune nephritis K Yoh, K Itoh, A Enomoto, A Hirayama, N Yamaguchi, M Kobayashi, ... Kidney international 60 (4), 1343-1353, 2001 | 425 | 2001 |
| Hyperglycemia induces oxidative and nitrosative stress and increases renal functional impairment in Nrf2‐deficient mice K Yoh, A Hirayama, K Ishizaki, A Yamada, M Takeuchi, S Yamagishi, ... Genes to Cells 13 (11), 1159-1170, 2008 | 249 | 2008 |
| A novel nonenzymatic pathway for the generation of nitric oxide by the reaction of hydrogen peroxide and D-or L-arginine S Nagase, K Takemura, A Ueda, A Hirayama, K Aoyagi, M Kondoh, ... Biochemical and biophysical research communications 233 (1), 150-153, 1997 | 232 | 1997 |
| The ROS scavenging and renal protective effects of pH-responsive nitroxide radical-containing nanoparticles T Yoshitomi, A Hirayama, Y Nagasaki Biomaterials 32 (31), 8021-8028, 2011 | 153 | 2011 |
| Nrf2 regulates the sensitivity of death receptor signals by affecting intracellular glutathione levels N Morito, K Yoh, K Itoh, A Hirayama, A Koyama, M Yamamoto, ... Oncogene 22 (58), 9275-9281, 2003 | 144 | 2003 |
| Redox regulation in radiation-induced cytochrome c release from mitochondria of human lung carcinoma A549 cells A Ogura, S Oowada, Y Kon, A Hirayama, H Yasui, S Meike, S Kobayashi, ... Cancer letters 277 (1), 64-71, 2009 | 120 | 2009 |
| pH-sensitive radical-containing-nanoparticle (RNP) for the L-band-EPR imaging of low pH circumstances T Yoshitomi, R Suzuki, T Mamiya, H Matsui, A Hirayama, Y Nagasaki Bioconjugate Chemistry 20 (9), 1792-1798, 2009 | 110 | 2009 |
| EPR imaging of reducing activity in Nrf2 transcriptional factor-deficient mice A Hirayama, K Yoh, S Nagase, A Ueda, K Itoh, N Morito, K Hirayama, ... Free Radical Biology and Medicine 34 (10), 1236-1242, 2003 | 95 | 2003 |
| Association of ecNOS gene polymorphisms with end stage renal diseases S Nagase, H Suzuki, Y Wang, S Kikuchi, A Hirayama, A Ueda, K Takada, ... Guanidino Compounds in Biology and Medicine, 113-118, 2003 | 89 | 2003 |
| Newly synthesized radical-containing nanoparticles enhance neuroprotection after cerebral ischemia-reperfusion injury A Marushima, K Suzuki, Y Nagasaki, T Yoshitomi, K Toh, H Tsurushima, ... Neurosurgery 68 (5), 1418-1426, 2011 | 86 | 2011 |
| Therapeutic efficacy of the Qing Dai in patients with intractable ulcerative colitis H Suzuki, T Kaneko, Y Mizokami, T Narasaka, S Endo, H Matsui, ... World journal of gastroenterology: WJG 19 (17), 2718, 2013 | 83 | 2013 |
| PPAR‐γ activator pioglitazone prevents age‐related atrial fibrillation susceptibility by improving antioxidant capacity and reducing apoptosis in a rat model D Xu, N Murakoshi, M Igarashi, A Hirayama, Y Ito, Y Seo, H Tada, ... Journal of Cardiovascular Electrophysiology 23 (2), 209-217, 2012 | 83 | 2012 |
| Neurovascular unit protection from cerebral ischemia–reperfusion injury by radical-containing nanoparticles in mice H Hosoo, A Marushima, Y Nagasaki, A Hirayama, H Ito, S Puentes, ... Stroke 48 (8), 2238-2247, 2017 | 72 | 2017 |
| In vivo imaging of oxidative stress in ischemia-reperfusion renal injury using electron paramagnetic resonance A Hirayama, S Nagase, A Ueda, T Oteki, K Takada, M Obara, M Inoue, ... American Journal of Physiology-Renal Physiology 288 (3), F597-F603, 2005 | 69 | 2005 |
| Inhibition of neutrophil superoxide production by uremic concentrations of guanidino compounds A Hirayama, AA Noronha-Dutra, MP Gordge, GH Neild, JS Hothersall Journal of the American Society of Nephrology 11 (4), 684-689, 2000 | 57 | 2000 |
| S-nitrosothiols are stored by platelets and released during platelet–neutrophil interactions A Hirayama, AA Noronha-Dutra, MP Gordge, GH Neild, JS Hothersall Nitric Oxide 3 (2), 95-104, 1999 | 54 | 1999 |
| Redox-active injectable gel using thermo-responsive nanoscale polyion complex flower micelle for noninvasive treatment of local inflammation ML Pua, T Yoshitomi, P Chonpathompikunlert, A Hirayama, Y Nagasaki Journal of controlled release 172 (3), 914-920, 2013 | 53 | 2013 |
| Hemodialysis does not influence the peroxidative state already present in uremia A Hirayama, S Nagase, M Gotoh, K Takemura, C Tomida, A Ueda, ... Nephron 86 (4), 436-440, 2000 | 52 | 2000 |
| Favorable effect of hemodialysis on decreased serum antioxidant activity in hemodialysis patients demonstrated by electron spin resonance. S Nagase, K Aoyagi, A Hirayama, M Gotoh, A Ueda, C Tomida, ... Journal of the American Society of Nephrology 8 (7), 1157-1163, 1997 | 51 | 1997 |
| Spherical carbon adsorbent (AST-120) protects deterioration of renal function in chronic kidney disease rats through inhibition of reactive oxygen species production from … S Owada, T Maeba, Y Sugano, A Hirayama, A Ueda, S Nagase, S Goto, ... Nephron Experimental Nephrology 115 (4), e101-e111, 2010 | 46 | 2010 |
