MiR-34a targeting of Notch ligand delta-like 1 impairs CD15+/CD133+ tumor-propagating cells and supports neural differentiation in medulloblastoma P de Antonellis, C Medaglia, E Cusanelli, I Andolfo, L Liguori, G De Vita, ... PloS one 6 (9), e24584, 2011 | 192 | 2011 |
Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d (TGGGGT)] 4 L Martino, A Virno, B Pagano, A Virgilio, S Di Micco, A Galeone, ... Journal of the American Chemical Society 129 (51), 16048-16056, 2007 | 186 | 2007 |
A new modified thrombin binding aptamer containing a 5′–5′ inversion of polarity site L Martino, A Virno, A Randazzo, A Virgilio, V Esposito, C Giancola, ... Nucleic acids research 34 (22), 6653-6662, 2006 | 110 | 2006 |
8-Methyl-2′-deoxyguanosine incorporation into parallel DNA quadruplex structures A Virgilio, V Esposito, A Randazzo, L Mayol, A Galeone Nucleic acids research 33 (19), 6188-6195, 2005 | 78 | 2005 |
Transferrin-conjugated SNALPs encapsulating 2′-O-methylated miR-34a for the treatment of multiple myeloma I Scognamiglio, MT Di Martino, V Campani, A Virgilio, A Galeone, A Gullà, ... BioMed research international 2014, 2014 | 60 | 2014 |
Effects of 8-methylguanine on structure, stability and kinetics of formation of tetramolecular quadruplexes PLT Tran, A Virgilio, V Esposito, G Citarella, JL Mergny, A Galeone Biochimie 93 (3), 399-408, 2011 | 55 | 2011 |
Human AP-endonuclease (Ape1) activity on telomeric G4 structures is modulated by acetylatable lysine residues in the N-terminal sequence S Burra, D Marasco, MC Malfatti, G Antoniali, A Virgilio, V Esposito, ... DNA repair 73, 129-143, 2019 | 50 | 2019 |
Design, synthesis, biophysical and biological studies of trisubstituted naphthalimides as G-quadruplex ligands A Peduto, B Pagano, C Petronzi, A Massa, V Esposito, A Virgilio, ... Bioorganic & medicinal chemistry 19 (21), 6419-6429, 2011 | 48 | 2011 |
Ptaquiloside, the major carcinogen of bracken fern, in the pooled raw milk of healthy sheep and goats: an underestimated, global concern of food safety A Virgilio, A Sinisi, V Russo, S Gerardo, A Santoro, A Galeone, ... Journal of agricultural and food chemistry 63 (19), 4886-4892, 2015 | 47 | 2015 |
Strand directionality affects cation binding and movement within tetramolecular G-quadruplexes P Šket, A Virgilio, V Esposito, A Galeone, J Plavec Nucleic Acids Research 40 (21), 11047-11057, 2012 | 47 | 2012 |
Site-specific replacement of the thymine methyl group by fluorine in thrombin binding aptamer significantly improves structural stability and anticoagulant activity A Virgilio, L Petraccone, V Vellecco, M Bucci, M Varra, C Irace, ... Nucleic Acids Research 43 (22), 10602-10611, 2015 | 45 | 2015 |
Site specific replacements of a single loop nucleoside with a dibenzyl linker may switch the activity of TBA from anticoagulant to antiproliferative M Scuotto, E Rivieccio, A Varone, D Corda, M Bucci, V Vellecco, G Cirino, ... Nucleic Acids Research 43 (16), 7702-7716, 2015 | 45 | 2015 |
A straightforward modification in the thrombin binding aptamer improving the stability, affinity to thrombin and nuclease resistance V Esposito, M Scuotto, A Capuozzo, R Santamaria, M Varra, L Mayol, ... Organic & Biomolecular Chemistry 12 (44), 8840-8843, 2014 | 43 | 2014 |
Effects of abasic sites on structural, thermodynamic and kinetic properties of quadruplex structures V Esposito, L Martino, G Citarella, A Virgilio, L Mayol, C Giancola, ... Nucleic acids research 38 (6), 2069-2080, 2010 | 43 | 2010 |
MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines P de Antonellis, L Liguori, A Falanga, M Carotenuto, V Ferrucci, I Andolfo, ... Naunyn-Schmiedeberg's archives of pharmacology 386, 287-302, 2013 | 41 | 2013 |
Effects of the introduction of inversion of polarity sites in the quadruplex forming oligonucleotide TGGGT V Esposito, A Virgilio, A Pepe, G Oliviero, L Mayol, A Galeone Bioorganic & medicinal chemistry 17 (5), 1997-2001, 2009 | 41 | 2009 |
The insertion of two 8-methyl-2′-deoxyguanosine residues in tetramolecular quadruplex structures: trying to orientate the strands A Virgilio, V Esposito, G Citarella, A Pepe, L Mayol, A Galeone Nucleic Acids Research 40 (1), 461-475, 2012 | 40 | 2012 |
A topological classification of G-quadruplex structures V Esposito, A Galeone, L Mayol, G Oliviero, A Virgilio, L Randazzo Nucleosides, Nucleotides and Nucleic Acids 26 (8-9), 1155-1159, 2007 | 39 | 2007 |
A new class of DNA quadruplexes formed by oligodeoxyribonucleotides containing a 3′-3′ or 5′-5′ inversion of polarity site V Esposito, A Virgilio, A Randazzo, A Galeone, L Mayol Chemical communications, 3953-3955, 2005 | 35 | 2005 |
miR-125b upregulates miR-34a and sequentially activates stress adaption and cell death mechanisms in multiple myeloma G Misso, MR Zarone, A Lombardi, A Grimaldi, AM Cossu, C Ferri, ... Molecular Therapy-Nucleic Acids 16, 391-406, 2019 | 33 | 2019 |