| Discovery, design, and synthesis of anti-metastatic lead phenylmethylene hydantoins inspired by marine natural products M Mudit, M Khanfar, A Muralidharan, S Thomas, GV Shah, ... Bioorganic & medicinal chemistry 17 (4), 1731-1738, 2009 | 96 | 2009 |
| Pachycladins A−E, Prostate Cancer Invasion and Migration Inhibitory Eunicellin-Based Diterpenoids from the Red Sea Soft Coral Cladiella pachyclados HM Hassan, MA Khanfar, AY Elnagar, R Mohammed, LA Shaala, ... Journal of natural products 73 (5), 848-853, 2010 | 90 | 2010 |
| Discovery of novel GSK-3β inhibitors with potent in vitro and in vivo activities and excellent brain permeability using combined ligand-and structure-based virtual screening MA Khanfar, RA Hill, A Kaddoumi, KA El Sayed Journal of medicinal chemistry 53 (24), 8534-8545, 2010 | 81 | 2010 |
| Latrunculin A and Its C-17-O-Carbamates Inhibit Prostate Tumor Cell Invasion and HIF-1 Activation in Breast Tumor Cells KAE Sayed, MA Khanfar, HM Shallal, A Muralidharan, B Awate, ... Journal of natural products 71 (3), 396-402, 2008 | 78 | 2008 |
| Rational design and semisynthesis of betulinic acid analogues as potent topoisomerase inhibitors FMA Bar, MA Khanfar, AY Elnagar, H Liu, AM Zaghloul, FA Badria, ... Journal of natural products 72 (9), 1643-1650, 2009 | 77 | 2009 |
| Marine sponge-derived sipholane triterpenoids reverse P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cells I Abraham, S Jain, CP Wu, MA Khanfar, Y Kuang, CL Dai, Z Shi, X Chen, ... Biochemical pharmacology 80 (10), 1497-1506, 2010 | 74 | 2010 |
| Olive oil‐derived oleocanthal as potent inhibitor of mammalian target of rapamycin: biological evaluation and molecular modeling studies MA Khanfar, SK Bardaweel, MR Akl, KA El Sayed Phytotherapy research 29 (11), 1776-1782, 2015 | 71 | 2015 |
| Design and pharmacophore modeling of biaryl methyl eugenol analogs as breast cancer invasion inhibitors FMA Bar, MA Khanfar, AY Elnagar, FA Badria, AM Zaghloul, KF Ahmad, ... Bioorganic & medicinal chemistry 18 (2), 496-507, 2010 | 60 | 2010 |
| Elaborate ligand-based modeling coupled with multiple linear regression and k nearest neighbor QSAR analyses unveiled new nanomolar mTOR inhibitors MA Khanfar, MO Taha Journal of chemical information and modeling 53 (10), 2587-2612, 2013 | 58 | 2013 |
| The marine natural-derived inhibitors of glycogen synthase kinase-3β phenylmethylene hydantoins: In vitro and in vivo activities and pharmacophore modeling MA Khanfar, BA Asal, M Mudit, A Kaddoumi, KA El Sayed Bioorganic & medicinal chemistry 17 (16), 6032-6039, 2009 | 58 | 2009 |
| Multiple targeting approaches on histamine H3 receptor antagonists MA Khanfar, A Affini, K Lutsenko, K Nikolic, S Butini, H Stark Frontiers in neuroscience 10, 190179, 2016 | 53 | 2016 |
| Pharmacophore modeling, homology modeling, and in silico screening reveal mammalian target of rapamycin inhibitory activities for sotalol, glyburide, metipranolol … MA Khanfar, MM AbuKhader, S Alqtaishat, MO Taha Journal of molecular Graphics and Modelling 42, 39-49, 2013 | 52 | 2013 |
| New Pim-1 kinase inhibitor from the co-culture of two sponge-associated actinomycetes SS El-Hawary, AM Sayed, R Mohammed, MA Khanfar, ME Rateb, ... Frontiers in Chemistry 6, 538, 2018 | 44 | 2018 |
| Semisynthetic latrunculin derivatives as inhibitors of metastatic breast cancer: biological evaluations, preliminary structure–activity relationship and molecular modeling studies MA Khanfar, DTA Youssef, KA El Sayed ChemMedChem: Chemistry Enabling Drug Discovery 5 (2), 274-285, 2010 | 43 | 2010 |
| The use of docking-based comparative intermolecular contacts analysis to identify optimal docking conditions within glucokinase and to discover of new GK activators MO Taha, M Habash, MA Khanfar Journal of computer-aided molecular design 28, 509-547, 2014 | 42 | 2014 |
| Identification of a small molecule class to enhance cell-cell adhesion and attenuate prostate tumor growth and metastasis GV Shah, A Muralidharan, S Thomas, M Gokulgandhi, M Mudit, M Khanfar, ... Molecular cancer therapeutics 8 (3), 509-520, 2009 | 42 | 2009 |
| Bioactive natural, biocatalytic, and semisynthetic tobacco cembranoids HN Baraka, MA Khanfar, JC Williams, EM El-Giar, KA El Sayed Planta medica 77 (05), 467-476, 2011 | 33 | 2011 |
| Discovery of novel urokinase plasminogen activator (uPA) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis MA Al-Sha’er, MA Khanfar, MO Taha Journal of molecular modeling 20, 1-15, 2014 | 32 | 2014 |
| The Veratrum alkaloids jervine, veratramine, and their analogues as prostate cancer migration and proliferation inhibitors: biological evaluation and … MA Khanfar, KA El Sayed Medicinal Chemistry Research 22, 4775-4786, 2013 | 32 | 2013 |
| Discovery of nanomolar phosphoinositide 3-kinase gamma (PI3Kγ) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis MO Taha, MA Al-Sha'er, MA Khanfar, AH Al-Nadaf European journal of medicinal chemistry 84, 454-465, 2014 | 31 | 2014 |
Khalid El SayedUniversity of Louisiana-MonroeVerified email at ulm.edu
