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Andrew I. Webb
Andrew I. Webb
Associate Professor - The Walter and Eliza Hall Institute
Verified email at wehi.edu.au
Title
Cited by
Cited by
Year
The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism
JM Murphy, PE Czabotar, JM Hildebrand, IS Lucet, JG Zhang, ...
Immunity 39 (3), 443-453, 2013
11202013
Linear ubiquitination prevents inflammation and regulates immune signalling
B Gerlach, SM Cordier, AC Schmukle, CH Emmerich, E Rieser, TL Haas, ...
Nature 471 (7340), 591-596, 2011
9582011
Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
JM Hildebrand, MC Tanzer, IS Lucet, SN Young, SK Spall, P Sharma, ...
Proceedings of the National Academy of Sciences 111 (42), 15072-15077, 2014
5452014
CIS is a potent checkpoint in NK cell–mediated tumor immunity
RB Delconte, TB Kolesnik, LF Dagley, J Rautela, W Shi, EM Putz, ...
Nature immunology 17 (7), 816-824, 2016
3272016
Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation
SL Masters, V Lagou, I Jéru, PJ Baker, L Van Eyck, DA Parry, D Lawless, ...
Science translational medicine 8 (332), 332ra45-332ra45, 2016
2972016
A type III effector antagonizes death receptor signalling during bacterial gut infection
JS Pearson, C Giogha, SY Ong, CL Kennedy, M Kelly, KS Robinson, ...
Nature 501 (7466), 247-251, 2013
2802013
Lack of prominent peptide–major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations
SJ Turner, K Kedzierska, H Komodromou, NL La Gruta, MA Dunstone, ...
Nature immunology 6 (4), 382-389, 2005
1782005
EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation
JS Pearson, C Giogha, S Mühlen, U Nachbur, CLL Pham, Y Zhang, ...
Nature microbiology 2 (4), 1-10, 2017
1752017
Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis
EJ Petrie, JJ Sandow, AV Jacobsen, BJ Smith, MDW Griffin, IS Lucet, ...
Nature communications 9 (1), 2422, 2018
1662018
A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production
U Nachbur, CA Stafford, A Bankovacki, Y Zhan, LM Lindqvist, BK Fiil, ...
Nature communications 6 (1), 6442, 2015
1262015
VDAC2 enables BAX to mediate apoptosis and limit tumor development
HS Chin, MX Li, IKL Tan, RL Ninnis, B Reljic, K Scicluna, LF Dagley, ...
Nature communications 9 (1), 4976, 2018
1202018
Necroptosis signalling is tuned by phosphorylation of MLKL residues outside the pseudokinase domain activation loop
MC Tanzer, A Tripaydonis, AI Webb, SN Young, LN Varghese, C Hall, ...
Biochemical Journal 471 (2), 255-265, 2015
1042015
A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1
J Le Nours, NA Gherardin, SH Ramarathinam, W Awad, F Wiede, ...
Science 366 (6472), 1522-1527, 2019
1012019
Lectin switching during dengue virus infection
W Dejnirattisai, AI Webb, V Chan, A Jumnainsong, A Davidson, ...
Journal of Infectious Diseases 203 (12), 1775-1783, 2011
982011
RIPLET, and not TRIM25, is required for endogenous RIG‐I‐dependent antiviral responses
TJ Hayman, AC Hsu, TB Kolesnik, LF Dagley, J Willemsen, MD Tate, ...
Immunology and cell biology 97 (9), 840-852, 2019
872019
Enrichment of extracellular vesicles from human synovial fluid using size exclusion chromatography
AD Foers, S Chatfield, LF Dagley, BJ Scicluna, AI Webb, L Cheng, AF Hill, ...
Journal of extracellular vesicles 7 (1), 1490145, 2018
852018
Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue
AI Webb, MA Dunstone, W Chen, MI Aguilar, Q Chen, H Jackson, ...
Journal of Biological Chemistry 279 (22), 23438-23446, 2004
822004
Viral MLKL homologs subvert necroptotic cell death by sequestering cellular RIPK3
EJ Petrie, JJ Sandow, WIL Lehmann, LY Liang, D Coursier, SN Young, ...
Cell reports 28 (13), 3309-3319. e5, 2019
812019
Human Bcl-2 antisense therapy for lymphomas
FE Cotter, A Webb, P Clarke, D Cunningham
Clinical Trials of Genetic Therapy with Antisense DNA and DNA Vectors, 169-189, 2020
802020
Structure of Plasmodium falciparum Rh5–CyRPA–Ripr invasion complex
W Wong, R Huang, S Menant, C Hong, JJ Sandow, RW Birkinshaw, ...
Nature 565 (7737), 118-121, 2019
802019
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