Design, synthesis, molecular modeling and biological evaluation of novel 1H-pyrazolo [3, 4-b] pyridine derivatives as potential anticancer agents IH Eissa, AM El-Naggar, MA El-Hashash Bioorganic chemistry 67, 43-56, 2016 | 127 | 2016 |
Eco-friendly synthesis of novel cyanopyridine derivatives and their anticancer and PIM-1 kinase inhibitory activities KAM Abouzid, GH Al-Ansary, AM El-Naggar European journal of medicinal chemistry 134, 357-365, 2017 | 74 | 2017 |
Design, synthesis, and SAR studies of novel 4-methoxyphenyl pyrazole and pyrimidine derivatives as potential dual tyrosine kinase inhibitors targeting both EGFR and VEGFR-2 AM El-Naggar, AMA Hassan, EB Elkaeed, MS Alesawy, AA Al‐Karmalawy Bioorganic Chemistry 123, 105770, 2022 | 65 | 2022 |
Design, eco-friendly synthesis, molecular modeling and anticancer evaluation of thiazol-5 (4 H)-ones as potential tubulin polymerization inhibitors targeting the colchicine … AM El-Naggar, IH Eissa, A Belal, AA El-Sayed RSC advances 10 (5), 2791-2811, 2020 | 65 | 2020 |
Synthesis, characterization and molecular docking studies of thiouracil derivatives as potent thymidylate synthase inhibitors and potential anticancer agents AM El-Naggar, MM Abou-El-Regal, SA El-Metwally, FF Sherbiny, IH Eissa Molecular diversity 21 (4), 967-983, 2017 | 65 | 2017 |
Design, efficient synthesis, docking studies, and anticancer evaluation of new quinoxalines as potential intercalative Topo II inhibitors and apoptosis inducers EM Abbass, AK Khalil, MM Mohamed, IH Eissa, AM El-Naggar Bioorganic chemistry 104, 104255, 2020 | 63 | 2020 |
Design and discovery of novel quinoxaline derivatives as dual DNA intercalators and topoisomerase II inhibitors IH Eissa, AM El-Naggar, NEA Abd El-Sattar, ASA Youssef Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2018 | 59 | 2018 |
Design, synthesis of new pyrimidine derivatives as anticancer and antimicrobial agents MM Mohamed, AK Khalil, EM Abbass, AM El-Naggar Synthetic Communications 47 (16), 1441-1457, 2017 | 49 | 2017 |
Design, synthesis and in silico studies of new quinazolinone derivatives as antitumor PARP-1 inhibitors SK Ramadan, EZ Elrazaz, KAM Abouzid, AM El-Naggar RSC advances 10 (49), 29475-29492, 2020 | 48 | 2020 |
Novel thiazole derivatives of medicinal potential: synthesis and modeling NEA Abdel-Sattar, AM El-Naggar, MSA Abdel-Mottaleb Journal of Chemistry 2017 (1), 4102796, 2017 | 42 | 2017 |
Metal salt-catalyzed diazocoupling of 3-substituted-1H-pyrazol-2-in-5-ones in aqueous medium AMES Ali Kh. Khalil, Mohamed A. Hassan, , Mohamed M. Mohamed Dyes and Pigments 66 (3), 241-245, 2005 | 42 | 2005 |
Synthesis, spectroscopic characterization and computational chemical study of 5-cyano-2-thiouracil derivatives as potential antimicrobial agents SA Rizk, AM El-Naggar, AA El-Badawy Journal of Molecular Structure 1155, 720-733, 2018 | 40 | 2018 |
Eco-friendly sequential one-pot synthesis, molecular docking, and anticancer evaluation of arylidene-hydrazinyl-thiazole derivatives as CDK2 inhibitors AM El-Naggar, MA El-Hashash, EB Elkaeed Bioorganic Chemistry 108, 104615, 2021 | 38 | 2021 |
Design, synthesis, and biological evaluation of novel pyrazole, oxazole, and pyridine derivatives as potential anticancer agents using mixed chalcone MH Ahmed, MA El‐Hashash, MI Marzouk, AM El‐Naggar Journal of Heterocyclic Chemistry 56 (1), 114-123, 2019 | 38 | 2019 |
Design, synthesis, anticancer evaluation and docking studies of new pyrimidine derivatives as potent thymidylate synthase inhibitors LHT Amin, TZ Shawer, AM El-Naggar, HMA El-Sehrawi Bioorganic Chemistry 91, 103159, 2019 | 37 | 2019 |
β‐Lactam Synthesis through Diodomethane Addition to Amide Dianions A Zidan, J Garrec, M Cordier, AM El‐Naggar, NEA Abd El‐Sattar, AK Ali, ... Angewandte Chemie 129 (40), 12347-12351, 2017 | 31 | 2017 |
Efficient synthesis of some pyrimidine and thiazolidine derivatives bearing quinoline scaffold under microwave irradiation AM El-Naggar, SK Ramadan Synthetic Communications 50 (14), 2188-2198, 2020 | 28 | 2020 |
An Efficient One‐Pot Synthesis of New Coumarin Derivatives as Potent Anticancer Agents under Microwave Irradiation AM El‐Naggar, MM Hemdan, SR Atta‐Allah Journal of Heterocyclic Chemistry 54 (6), 3519-3526, 2017 | 26 | 2017 |
Eco‐friendly synthesis of novel pyrimidine derivatives as potential anticancer agents EM Abbass, AK Khalil, AM El‐Naggar Journal of Heterocyclic Chemistry, 2020 | 25 | 2020 |
Synthesis of new oxadiazol-phthalazinone derivatives with anti-proliferative activity; molecular docking, pro-apoptotic, and enzyme inhibition profile MH Hekal, AM El-Naggar, FSMA El-Azm, WM El-Sayed RSC advances 10 (7), 3675-3688, 2020 | 25 | 2020 |