Abhinav Tiwari
Abhinav Tiwari
Pfizer
بريد إلكتروني تم التحقق منه على rice.edu
عنوان
عدد مرات الاقتباسات
عدد مرات الاقتباسات
السنة
Bistable responses in bacterial genetic networks: designs and dynamical consequences
A Tiwari, JCJ Ray, J Narula, OA Igoshin
Mathematical biosciences 231 (1), 76-89, 2011
652011
The interplay of multiple feedback loops with post-translational kinetics results in bistability of mycobacterial stress response
A Tiwari, G Balázsi, ML Gennaro, OA Igoshin
Physical biology 7 (3), 036005, 2010
582010
Tunable protease-activatable virus nanonodes
J Judd, ML Ho, A Tiwari, EJ Gomez, C Dempsey, K Van Vliet, OA Igoshin, ...
ACS nano 8 (5), 4740-4746, 2014
392014
Coupling between feedback loops in autoregulatory networks affects bistability range, open-loop gain and switching times
A Tiwari, OA Igoshin
Physical biology 9 (5), 055003, 2012
332012
Is there a case for selectively promiscuous anticancer drugs?
A Fernández, A Crespo, A Tiwari
Drug discovery today 14 (1-2), 1-5, 2009
332009
Mathematical model of a gene regulatory network reconciles effects of genetic perturbations on hematopoietic stem cell emergence
J Narula, CJ Williams, A Tiwari, J Marks-Bluth, JE Pimanda, OA Igoshin
Developmental biology 379 (2), 258-269, 2013
222013
The Role of Aggregates of Therapeutic Protein Products in Immunogenicity: An Evaluation by Mathematical Modeling
L Yin, X Chen, A Tiwari, P Vicini, TP Hickling
Journal of Immunology Research, 2015
182015
A mechanistic PK/PD model for two anti-IL13 antibodies explains the difference in total IL-13 accumulation observed in clinical studies
A Tiwari, M Kasaian, AC Heatherington, HM Jones, F Hua
MAbs 8 (5), 983-990, 2016
122016
Unraveling the regulatory connections between two controllers of breast cancer cell fate
J Lee, A Tiwari, V Shum, GB Mills, MA Mancini, OA Igoshin, G Balázsi
Nucleic acids research 42 (11), 6839-6849, 2014
102014
Developability of Biotherapeutics: computational approaches
S Kumar, SK Singh
CRC Press, 2015
82015
Role of autoregulation and relative synthesis of operon partners in alternative sigma factor networks
J Narula, A Tiwari, OA Igoshin
PLoS computational biology 12 (12), e1005267, 2016
52016
Optimal affinity of a monoclonal antibody: guiding principles using mechanistic modeling
A Tiwari, AK Abraham, JM Harrold, A Zutshi, P Singh
The AAPS journal 19 (2), 510-519, 2017
42017
Assessing the Impact of Tissue Target Concentration Data on Uncertainty in In Vivo Target Coverage Predictions
A Tiwari, H Luo, X Chen, P Singh, I Bhattacharya, P Jasper, JE Tolsma, ...
CPT: pharmacometrics & systems pharmacology 5 (10), 565-574, 2016
42016
Application of Mechanistic Pharmacokinetic–Pharmacodynamic Modeling toward the Development of Biologics
P Singh, A Tiwari, AK Abraham, A Zutshi
Developability of Biotherapeutics: Computational Approaches, 109, 2015
32015
Importance of feedback and feedforward loops to adaptive immune response modeling
A Rahman, A Tiwari, J Narula, T Hickling
CPT: pharmacometrics & systems pharmacology 7 (10), 621-628, 2018
12018
Comparing Model Performance in Characterizing the PK/PD of the Anti‐Myostatin Antibody Domagrozumab
A Tiwari, I Bhattacharya, PLS Chan, L Harnisch
Clinical and translational science 13 (1), 125-136, 2020
2020
POPULATION PHARMACOKINETIC MODELING OF PF-06823859, AN ANTI-IFN beta ANTIBODY, IN HEALTHY SUBJECTS.
A Tiwari, NJ Rath, S Tarabar, K Johnson, BS Oemar
CLINICAL PHARMACOLOGY & THERAPEUTICS 103, S89-S90, 2018
2018
Predicting clinical immunogenicity for biotherapeutics using a systems model of the immune response
A Tiwari, Z Zhang, J Pappas, I Bhattacharya, C Lepsy, X Chen, ...
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 44, S17-S18, 2017
2017
Role of stoichiometry and implicit negative feedback in sigma factor regulation
J Narula, A Tiwari, OA Igoshin
bioRxiv, 032359, 2015
2015
Uncovering Mechanisms of Bistability and Ultrasensitivity in Bacterial Stress Response
A Tiwari
https://scholarship.rice.edu/bitstream/handle/1911/77560 …, 2013
2013
يتعذر على النظام إجراء العملية في الوقت الحالي. عاود المحاولة لاحقًا.
مقالات 1–20