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Prashant Thakkar
Prashant Thakkar
Weill Cornell Medicine
Verified email at med.cornell.edu
Title
Cited by
Cited by
Year
DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria
LS Shock, PV Thakkar, EJ Peterson, RG Moran, SM Taylor
Proceedings of the National Academy of Sciences 108 (9), 3630-3635, 2011
5572011
Identification of low abundance microbiome in clinical samples using whole genome sequencing
C Zhang, K Cleveland, F Schnoll-Sussman, B McClure, M Bigg, P Thakkar, ...
Genome biology 16, 1-16, 2015
922015
Multicenter, randomized phase II study of neoadjuvant pembrolizumab plus chemotherapy and chemoradiotherapy in esophageal adenocarcinoma (EAC).
MA Shah, K Almhanna, S Iqbal, P Thakkar, BJ Schneider, R Yantiss, Y Wu, ...
Journal of Clinical Oncology 39 (15_suppl), 4005-4005, 2021
262021
Microtubule engagement with taxane is altered in taxane-resistant gastric cancer
G Galletti, C Zhang, A Gjyrezi, K Cleveland, J Zhang, S Powell, ...
Clinical Cancer Research 26 (14), 3771-3783, 2020
212020
Impact of antibiotic use on response to treatment with immune checkpoint inhibitors.
U Khan, C Peña, J Brouwer, K Hoffman, AR Choudhury, C Zhang, ...
Journal of Clinical Oncology 37 (4_suppl), 143-143, 2019
142019
A comparison of homogenization vs. enzymatic lysis for microbiome profiling in clinical endoscopic biopsy tissue samples
C Zhang, PV Thakkar, SE Powell, P Sharma, S Vennelaganti, D Betel, ...
Frontiers in Microbiology 9, 3246, 2019
112019
Multicenter phase II study of cabazitaxel in advanced gastroesophageal cancer: association of HER2 expression and M2-Like tumor-associated macrophages with patient outcome
MA Shah, P Enzinger, AH Ko, AJ Ocean, PA Philip, PV Thakkar, ...
Clinical Cancer Research 26 (18), 4756-4766, 2020
92020
CLIP-170S is a microtubule+ TIP variant that confers resistance to taxanes by impairing drug-target engagement
PV Thakkar, K Kita, U Del Castillo, G Galletti, N Madhukar, EV Navarro, ...
Developmental cell 56 (23), 3264-3275. e7, 2021
52021
Understanding associations among local microbiome, immune response, and efficacy of immunotherapy in esophageal cancer
C Zhang, PV Thakkar, P Sharma, S Vennelaganti, D Betel, MA Shah
Cancer Research 79 (13_Supplement), 2826-2826, 2019
32019
Cediranib reverses taxane resistance in CLIP-170S expressing gastric cancer
WG Stone, U Castillo, PV Thakkar, MA Shah, P Giannakakou
Cancer Research 83 (7_Supplement), 1742-1742, 2023
12023
Imatinib overrides taxane resistance by selective inhibition of novel CLIP1 variant obstructing the microtubule pore
K Kita, PV Thakkar, G Galletti, N Madhukar, EV Navarro, I Barasoain, ...
bioRxiv, 838334, 2019
12019
Understanding the association of gut microbiota and tumor microenvironment in gastric and esophageal cancer
PV Thakkar, C Zhang, P Sharma, S Vennelaganti, D Betel, MA Shah
Cancer Research 78 (13_Supplement), 5128-5128, 2018
12018
Elucidation of mechanisms generating 5-hydroxymethylcytosine (5hmC) in mammalian mitochondria
PV Thakkar
Virginia Commonwealth University, 2013
12013
A novel mitochondrial isoform of mammalian DNA methyltransferase 1
LM Shock, PV Thakkar, EJ Peterson, RG Moran, SM Taylor
Cancer Research 70 (8_Supplement), 4803-4803, 2010
12010
Gastric Cancer Tumor Immune Microenvironment Landscape: Clinical Implications for Patient Outcome and Response to PD-1 Immune Checkpoint Blockade
M Shah, S Sarkar, D Melikhova, P Thakkar, O Kudryashova, N Shin, ...
2024
Immunoblot Analysis from Single Cells Using Milo™ Single-Cell Western Platform
PV Thakkar
Single Cell Analysis: Methods and Protocols, 201-214, 2024
2024
Variants of CLIP-170 associated with taxane resistance in tumors
PV Thakkar, K Kita, U del Castillo, WG Stone, G Galletti, N Madhukar, ...
Cancer Research 82 (12_Supplement), 2623-2623, 2022
2022
Tumor immune microenvironment based molecular functional clustering reveals a prognostic signature that predicts overall survival in patients with gastric cancer
PV Thakkar, O Kudryashova, D Melikhova, N Samarina, S Degryse, ...
Cancer Research 81 (13_Supplement), 3182-3182, 2021
2021
Systems biology identifies Gleevec as a specific inhibitor of CLIP-170S, a novel+ TIP isoform, which causes taxane resistance in cancer cells and patients by obstructing the …
PV Thakkar, K Kita, G Galletti, N Madhukar, EV Navarro, K Cleveland, ...
Cancer Research 80 (16_Supplement), 641-641, 2020
2020
Single cell RNA sequencing of esophageal adenocarcinoma before and after chemotherapy alone and with pembrolizumab identifies novel tumor immune microenvironment alterations
PV Thakkar, S Sarkar, C Zhang, D Elmonshed, E Futamura, D Betel, ...
Cancer Research 80 (16_Supplement), 975-975, 2020
2020
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