| MHC-linked LMP gene products specifically alter peptidase activities of the proteasome J Driscoll, MG Brown, D Finley, JJ Monaco Nature 365 (6443), 262-264, 1993 | 628 | 1993 |
| Structural and serological similarity of MHC-linked LMP and proteasome (multicatalytic proteinase) complexes MG Brown, J Driscoll, JJ Monaco Nature 353 (6342), 355-357, 1991 | 439 | 1991 |
| The proteasome (multicatalytic protease) is a component of the 1500-kDa proteolytic complex which degrades ubiquitin-conjugated proteins. J Driscoll, AL Goldberg Journal of Biological Chemistry 265 (9), 4789-4792, 1990 | 407 | 1990 |
| Proteasome subunits encoded in the MHC are not generally required for the processing of peptides bound by MHC class I molecules D Arnold, J Driscoll, M Androlewicz, E Hughes, P Cresswell, T Spies Nature 360 (6400), 171-174, 1992 | 270 | 1992 |
| Novel therapies emerging in oncology to target the TGF-β pathway D Kim, Malek, Choi, Ignatz-Hoover J Hematology & Oncology 14 (55), https://doi.org/10.1186/s13045-021-0105, 2021 | 244* | 2021 |
| Correlation of long non-coding RNA expression with metastasis, drug resistance and clinical outcome in cancer E Malek, S Jagannathan, JJ Driscoll Oncotarget 5 (18), 8027, 2014 | 216 | 2014 |
| Involvement of the proteasome in various degradative processes in mammalian cells. W Matthews, J Driscoll, K Tanaka, A Ichihara, AL Goldberg Proceedings of the National Academy of Sciences 86 (8), 2597-2601, 1989 | 202 | 1989 |
| Overall survival: still the gold standard: why overall survival remains the definitive end point in cancer clinical trials JJ Driscoll, O Rixe The Cancer Journal 15 (5), 401-405, 2009 | 175 | 2009 |
| Myeloid-derived suppressor cells: The green light for myeloma immune escape E Malek, M de Lima, JJ Letterio, BG Kim, JH Finke, JJ Driscoll, SA Giralt Blood reviews 30 (5), 341-348, 2016 | 142 | 2016 |
| Skeletal muscle proteasome can degrade proteins in an ATP-dependent process that does not require ubiquitin. J Driscoll, AL Goldberg Proceedings of the National Academy of Sciences 86 (3), 787-791, 1989 | 127 | 1989 |
| The sumoylation pathway is dysregulated in multiple myeloma and is associated with adverse patient outcome JJ Driscoll, D Pelluru, K Lefkimmiatis, M Fulciniti, RH Prabhala, PR Greipp, ... Blood, The Journal of the American Society of Hematology 115 (14), 2827-2834, 2010 | 126 | 2010 |
| Pharmacologic screens reveal metformin that suppresses GRP78-dependent autophagy to enhance the anti-myeloma effect of bortezomib S Jagannathan, MAY Abdel-Malek, E Malek, N Vad, T Latif, KC Anderson, ... Leukemia 29 (11), 2184-2191, 2015 | 115 | 2015 |
| Comparison of cell lines deficient in antigen presentation reveals a functional role for TAP-1 alone in antigen processing. R Gabathuler, G Reid, G Kolaitis, J Driscoll, WA Jefferies The Journal of experimental medicine 180 (4), 1415-1425, 1994 | 109 | 1994 |
| Molecular chaperone GRP78 enhances aggresome delivery to autophagosomes to promote drug resistance in multiple myeloma MAYA Malek, S Jagannathan, E Malek, DM Sayed, SA Elgammal, ... Oncotarget 6 (5), 3098, 2015 | 85 | 2015 |
| Hidradenocarcinomas: a brief review and future directions S Gauerke, JJ Driscoll Archives of pathology & laboratory medicine 134 (5), 781-785, 2010 | 84 | 2010 |
| A calcium-activated protease from Alzheimer's disease brain cleaves at the N-terminus of the amyloid β-protein CR Abraham, J Driscoll, H Potter, WE Van Nostrand, P Tempst Biochemical and biophysical research communications 174 (2), 790-796, 1991 | 79 | 1991 |
| MiR-29b replacement inhibits proteasomes and disrupts aggresome+ autophagosome formation to enhance the antimyeloma benefit of bortezomib S Jagannathan, N Vad, S Vallabhapurapu, KC Anderson, JJ Driscoll Leukemia 29 (3), 727-738, 2015 | 78 | 2015 |
| MHC-linked low-molecular mass polypeptide subunits define distinct subsets of proteasomes. Implications for divergent function among distinct proteasome subsets. MG Brown, J Driscoll, JJ Monaco Journal of immunology (Baltimore, Md.: 1950) 151 (3), 1193-1204, 1993 | 76 | 1993 |
| A controlled breakdown: antigen processing and the turnover of viral proteins J Driscoll, D Finley Cell 68 (5), 823-825, 1992 | 73 | 1992 |
| MicroRNA theragnostics for the clinical management of multiple myeloma N Ahmad, S Haider, S Jagannathan, E Anaissie, JJ Driscoll Leukemia 28 (4), 732-738, 2014 | 70 | 2014 |
Ehsan MalekAssociate Professor, Roswell Park Comprehensive Cancer CenterVerified email at RoswellPark.org
