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Michael Tymianski
Michael Tymianski
University Health Network
Verified email at uhn.ca
Title
Cited by
Cited by
Year
Unruptured intracranial aneurysms—risk of rupture and risks of surgical intervention
International Study of Unruptured Intracranial Aneurysms Investigators
New England Journal of Medicine 339 (24), 1725-1733, 1998
16181998
Glutamate receptors, neurotoxicity and neurodegeneration
A Lau, M Tymianski
Pflügers Archiv-European Journal of Physiology 460, 525-542, 2010
14482010
Treatment of ischemic brain damage by perturbing NMDA receptor-PSD-95 protein interactions
M Aarts, Y Liu, L Liu, S Besshoh, M Arundine, JW Gurd, YT Wang, ...
Science 298 (5594), 846-850, 2002
12792002
Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity
M Arundine, M Tymianski
Cell calcium 34 (4-5), 325-337, 2003
11122003
Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein
R Sattler, Z Xiong, WY Lu, M Hafner, JF MacDonald, M Tymianski
Science 284 (5421), 1845-1848, 1999
11041999
NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo
Y Liu, TP Wong, M Aarts, A Rooyakkers, L Liu, TW Lai, DC Wu, J Lu, ...
Journal of Neuroscience 27 (11), 2846-2857, 2007
10232007
Calcium, ischemia and excitotoxicity
K Szydlowska, M Tymianski
Cell calcium 47 (2), 122-129, 2010
9972010
A key role for TRPM7 channels in anoxic neuronal death
M Aarts, K Iihara, WL Wei, ZG Xiong, M Arundine, W Cerwinski, ...
Cell 115 (7), 863-877, 2003
9632003
Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury
M Arundine, M Tymianski
Cellular and Molecular Life Sciences CMLS 61, 657-668, 2004
9072004
Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons
M Tymianski, MP Charlton, PL Carlen, CH Tator
Journal of Neuroscience 13 (5), 2085-2104, 1993
7681993
Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death
R Sattler, M Tymianski
Molecular neurobiology 24, 107-129, 2001
7522001
Molecular mechanisms of calcium-dependent excitotoxicity
R Sattler, M Tymianski
Journal of molecular medicine 78, 3-13, 2000
6542000
Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial
MD Hill, M Goyal, BK Menon, RG Nogueira, RA McTaggart, AM Demchuk, ...
The Lancet 395 (10227), 878-887, 2020
5532020
The natural history and predictive features of hemorrhage from brain arteriovenous malformations
L da Costa, MC Wallace, KG Ter Brugge, C O'Kelly, RA Willinsky, ...
Stroke 40 (1), 100-105, 2009
4962009
Normal and abnormal calcium homeostasis in neurons: a basis for the pathophysiology of traumatic and ischemic central nervous system injury
M Tymianski, CH Tator
Neurosurgery 38 (6), 1176-1195, 1996
4951996
Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain
DJ Cook, L Teves, M Tymianski
Nature 483 (7388), 213-217, 2012
4882012
Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain
SI Nikolaev, S Vetiska, X Bonilla, E Boudreau, S Jauhiainen, ...
New England Journal of Medicine 378 (3), 250-261, 2018
4442018
Safety and efficacy of NA-1 in patients with iatrogenic stroke after endovascular aneurysm repair (ENACT): a phase 2, randomised, double-blind, placebo-controlled trial
MD Hill, RH Martin, D Mikulis, JH Wong, FL Silver, G Milot, WM Clark, ...
The Lancet Neurology 11 (11), 942-950, 2012
4332012
Distinct influx pathways, not calcium load, determine neuronal vulnerability to calcium neurotoxicity
R Sattler, MP Charlton, M Hafner, M Tymianski
Journal of neurochemistry 71 (6), 2349-2364, 1998
3641998
Targeting NMDA receptors in stroke: new hope in neuroprotection
QJ Wu, M Tymianski
Molecular brain 11, 1-14, 2018
3362018
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