M.L. Hekkelman
M.L. Hekkelman
bioinformaticus, NKI
Verified email at
Cited by
Cited by
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfaces
H Venselaar, TAH Te Beek, RKP Kuipers, ML Hekkelman, G Vriend
BMC bioinformatics 11 (1), 1-10, 2010
A series of PDB related databases for everyday needs
RP Joosten, TAH Te Beek, E Krieger, ML Hekkelman, RWW Hooft, ...
Nucleic acids research 39 (suppl_1), D411-D419, 2010
WIWS: a protein structure bioinformatics Web service collection
ML Hekkelman, TAH te Beek, SR Pettifer, D Thorne, TK Attwood, G Vriend
Nucleic acids research 38 (suppl_2), W719-W723, 2010
Identification of novel functional TBP‐binding sites and general factor repertoires
S Denissov, M Van Driel, R Voit, M Hekkelman, T Hulsen, N Hernandez, ...
The EMBO journal 26 (4), 944-954, 2007
Homology modelling and spectroscopy, a never-ending love story
H Venselaar, RP Joosten, B Vroling, CAB Baakman, ML Hekkelman, ...
European Biophysics Journal 39 (4), 551-563, 2010
MRS: a fast and compact retrieval system for biological data
ML Hekkelman, G Vriend
Nucleic Acids Research 33 (suppl_2), W766-W769, 2005
The EMBRACE web service collection
S Pettifer, J Ison, M Kalaš, D Thorne, P McDermott, I Jonassen, A Liaquat, ...
Nucleic acids research 38 (suppl_2), W683-W688, 2010
A global Ramachandran score identifies protein structures with unlikely stereochemistry
OV Sobolev, PV Afonine, NW Moriarty, ML Hekkelman, RP Joosten, ...
Structure 28 (11), 1249-1258. e2, 2020
Signature, a web server for taxonomic characterization of sequence samples using signature genes
BE Dutilh, Y He, ML Hekkelman, MA Huynen
Nucleic acids research 36 (suppl_2), W470-W474, 2008
Homology-based loop modeling yields more complete crystallographic protein structures
B van Beusekom, K Joosten, ML Hekkelman, RP Joosten, A Perrakis
IUCrJ 5 (5), 585-594, 2018
AlphaFill: enriching the AlphaFold models with ligands and co-factors
ML Hekkelman, I de Vries, RP Joosten, A Perrakis
bioRxiv, 2021
Building and rebuilding N-glycans in protein structure models
B van Beusekom, N Wezel, ML Hekkelman, A Perrakis, P Emsley, ...
Acta Crystallographica Section D: Structural Biology 75 (4), 416-425, 2019
GeneE: gene and protein query expansion with disambiguation
MJ Schuemie, N Kang, ML Hekkelman, JA Kors
Bioinformatics 26 (1), 147-148, 2010
Functional radiogenetic profiling implicates ERCC6L2 in non-homologous end joining
P Francica, M Mutlu, VA Blomen, C Oliveira, Z Nowicka, A Trenner, ...
Cell reports 32 (8), 108068, 2020
West-Life: A virtual research environment for structural biology
C Morris, P Andreetto, L Banci, AMJJ Bonvin, G Chojnowski, L Del Cano, ...
Journal of Structural Biology: X 1, 100006, 2019
The cohesin acetylation cycle controls chromatin loop length through a PDS5A brake mechanism
MS van Ruiten, D van Gent, Á Sedeño Cacciatore, A Fauster, L Willems, ...
Nature structural & molecular biology, 1-6, 2022
LAHMA: structure analysis through local annotation of homology-matched amino acids
B van Beusekom, G Damaskos, ML Hekkelman, F Salgado-Polo, ...
Acta Crystallographica Section D: Structural Biology 77 (1), 28-40, 2021
Zero Ramachandran outliers does not guarantee a “good” model
O Sobolev, P Afonine, N Moriarty, M Hekkelman, R Joosten, A Perrakis, ...
Acta Crystallographica Section A: Foundations and Advances 76, a24-a24, 2020
3D-Beacons: Decreasing the gap between protein sequences and structures through a federated network of protein structure data resources
M Varadi, SS Nair, I Sillitoe, G Tauriello, S Anyango, S Bienert, C Borges, ...
bioRxiv, 2022
New restraints and validation approaches for nucleic acid structures in PDB-REDO
I de Vries, T Kwakman, XJ Lu, ML Hekkelman, M Deshpande, S Velankar, ...
Acta Crystallographica Section D: Structural Biology 77 (9), 2021
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