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Rikke Hahn Kofoed
Rikke Hahn Kofoed
Post doctoral fellow, Aarhus University and Aarhus University Hospital, Denmark
Bestätigte E-Mail-Adresse bei sri.utoronto.ca
Titel
Zitiert von
Zitiert von
Jahr
Alpha‐synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation
C Betzer, LB Lassen, A Olsen, RH Kofoed, L Reimer, E Gregersen, ...
EMBO reports 19 (5), e44617, 2018
1052018
ELISA method to detect α-synuclein oligomers in cell and animal models
LB Lassen, E Gregersen, AK Isager, C Betzer, RH Kofoed, PH Jensen
PloS one 13 (4), e0196056, 2018
662018
Focused ultrasound as a novel strategy for noninvasive gene delivery to retinal Müller glia
Y Touahri, R Dixit, RH Kofoed, K Mikloska, EJ Park, R Raeisossadati, ...
Theranostics 10 (7), 2982, 2020
282020
Strategy to enhance transgene expression in proximity of amyloid plaques in a mouse model of Alzheimer's disease
D Weber-Adrian, RH Kofoed, JWY Chan, J Silburt, Z Noroozian, S Kügler, ...
Theranostics 9 (26), 8127, 2019
252019
Inflammation kinase PKR phosphorylates α-synuclein and causes α-synuclein-dependent cell death
L Reimer, LB Vesterager, C Betzer, J Zheng, LD Nielsen, RH Kofoed, ...
Neurobiology of disease 115, 17-28, 2018
252018
PKR kinase directly regulates tau expression and Alzheimer's disease‐related tau phosphorylation
L Reimer, C Betzer, RH Kofoed, C Volbracht, K Fog, C Kurhade, E Nilsson, ...
Brain Pathology 31 (1), 103-119, 2021
232021
Ultrasound delivery of a TrkA agonist confers neuroprotection to Alzheimer-associated pathologies
K Xhima, K Markham-Coultes, R Hahn Kofoed, HU Saragovi, K Hynynen, ...
Brain 145 (8), 2806-2822, 2022
222022
Polo-like kinase 2 modulates α-synuclein protein levels by regulating its mRNA production
RH Kofoed, J Zheng, N Ferreira, S Lykke-Andersen, M Salvi, C Betzer, ...
Neurobiology of disease 106, 49-62, 2017
222017
Efficacy of gene delivery to the brain using AAV and ultrasound depends on serotypes and brain areas
RH Kofoed, CL Dibia, K Noseworthy, K Xhima, N Vacaresse, K Hynynen, ...
Journal of Controlled Release 351, 667-680, 2022
202022
Systemic AAV6-synapsin-GFP administration results in lower liver biodistribution, compared to AAV1&2 and AAV9, with neuronal expression following ultrasound-mediated brain delivery
D Weber-Adrian, RH Kofoed, J Silburt, Z Noroozian, K Shah, A Burgess, ...
Scientific Reports 11 (1), 1934, 2021
142021
Glycogen synthase kinase 3 β activity is essential for Polo-like kinase 2-and Leucine-rich repeat kinase 2-mediated regulation of α-synuclein
RH Kofoed, C Betzer, N Ferreira, PH Jensen
Neurobiology of Disease 136, 104720, 2020
142020
Transgene distribution and immune response after ultrasound delivery of rAAV9 and PHP. B to the brain in a mouse model of amyloidosis
RH Kofoed, S Heinen, J Silburt, S Dubey, CL Dibia, M Maes, EM Simpson, ...
Molecular Therapy-Methods & Clinical Development 23, 390-405, 2021
132021
Viral alpha-synuclein knockdown prevents spreading synucleinopathy
S Menon, RH Kofoed, F Nabbouh, K Xhima, Y Al-Fahoum, T Langman, ...
Brain Communications 3 (4), fcab247, 2021
92021
Investigation of RNA synthesis using 5-bromouridine labelling and immunoprecipitation
RH Kofoed, C Betzer, S Lykke-Andersen, E Molska, PH Jensen
JoVE (Journal of Visualized Experiments), e57056, 2018
62018
The engineered AAV2-HBKO promotes non-invasive gene delivery to large brain regions beyond ultrasound targeted sites
RH Kofoed, K Noseworthy, K Wu, S Sivadas, L Stanek, B Elmer, ...
Molecular Therapy-Methods & Clinical Development 27, 167-184, 2022
52022
Using focused ultrasound to modulate microglial structure and function
S Grewal, E Gonçalves de Andrade, RH Kofoed, PM Matthews, I Aubert, ...
Frontiers in Cellular Neuroscience 17, 1290628, 2023
12023
Sonoselective delivery using ultrasound and microbubbles combined with intravenous rAAV9 CLDN5-GFP does not increase endothelial gene expression
RH Kofoed, EM Simpson, K Hynynen, I Aubert
Gene Therapy 30 (12), 807-811, 2023
12023
The Impact of Serotypes and Anatomical Regions on the Efficacy of Focused Ultrasound-Mediated AAV Delivery to the Brain
RH Kofoed, K Noseworthy, C Dibia, N Vacaresse, K Hynynen, I Aubert
MOLECULAR THERAPY 29 (4), 180-180, 2021
12021
The Use of Co-immunoprecipitation to Study Conformation-Specific Protein Interactions of Oligomeric α-Synuclein Aggregates
C Betzer, RH Kofoed, PH Jensen
Co-Immunoprecipitation Methods for Brain Tissue, 23-36, 2019
12019
Science around the world
P Antas, A Cleveland, P Contessotto, R Schaffrath
Trends in molecular medicine, 2024
2024
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