| Speciation and structure of ferriprotoporphyrin IX in aqueous solution: spectroscopic and diffusion measurements demonstrate dimerization, but not μ-oxo dimer formation KA de Villiers, CH Kaschula, TJ Egan, HM Marques JBIC Journal of Biological Inorganic Chemistry 12 (1), 101-117, 2007 | 182 | 2007 |
| Haemozoin (β-haematin) biomineralization occurs by self-assembly near the lipid/water interface TJ Egan, JYJ Chen, KA de Villiers, TE Mabotha, KJ Naidoo, KK Ncokazi, ... FEBS letters 580 (21), 5105-5110, 2006 | 174 | 2006 |
| The crystal structure of halofantrine–ferriprotoporphyrin IX and the mechanism of action of arylmethanol antimalarials KA de Villiers, HM Marques, TJ Egan Journal of inorganic biochemistry 102 (8), 1660-1667, 2008 | 147 | 2008 |
| Speciation of ferriprotoporphyrin IX in aqueous and mixed aqueous solution is controlled by solvent identity, pH, and salt concentration C Asher, KA de Villiers, TJ Egan Inorganic chemistry 48 (16), 7994-8003, 2009 | 99 | 2009 |
| Crystallization of synthetic haemozoin (β-haematin) nucleated at the surface of lipid particles AN Hoang, KK Ncokazi, KA de Villiers, DW Wright, TJ Egan Dalton Transactions 39 (5), 1235-1244, 2010 | 94 | 2010 |
| The single crystal X-ray structure of β-hematin DMSO solvate grown in the presence of chloroquine, a β-hematin growth-rate inhibitor J Gildenhuys, T Roex, TJ Egan, KA de Villiers Journal of the American Chemical Society 135 (3), 1037-1047, 2013 | 83 | 2013 |
| Iron (III) protoporphyrin IX complexes of the antimalarial cinchona alkaloids quinine and quinidine KA de Villiers, J Gildenhuys, T le Roex ACS chemical biology 7 (4), 666-671, 2012 | 81 | 2012 |
| Recent advances in the discovery of haem-targeting drugs for malaria and schistosomiasis KA De Villiers, TJ Egan Molecules 14 (8), 2868-2887, 2009 | 68 | 2009 |
| Solvent-induced effects: self-association of positively charged π systems E Buisine, K De Villiers, TJ Egan, C Biot Journal of the American Chemical Society 128 (37), 12122-12128, 2006 | 55 | 2006 |
| Discriminating the intraerythrocytic lifecycle stages of the malaria parasite using synchrotron FT-IR microspectroscopy and an artificial neural network GT Webster, KA De Villiers, TJ Egan, S Deed, L Tilley, MJ Tobin, ... Analytical chemistry 81 (7), 2516-2524, 2009 | 51 | 2009 |
| Discriminating the intraerythrocytic lifecycle stages of the malaria parasite using synchrotron FT-IR microspectroscopy and an artificial neural network GT Webster, KA De Villiers, TJ Egan, S Deed, L Tilley, MJ Tobin, ... Analytical chemistry 81 (7), 2516-2524, 2009 | 51 | 2009 |
| Oriented nucleation of β-hematin crystals induced at various interfaces: Relevance to hemozoin formation KA de Villiers, M Osipova, TE Mabotha, I Solomonov, Y Feldman, K Kjaer, ... Crystal Growth and Design 9 (1), 626-632, 2008 | 32 | 2008 |
| Hemozoin inhibiting 2-phenylbenzimidazoles active against malaria parasites FP L'abbate, R Müller, R Openshaw, JM Combrinck, KA de Villiers, ... European journal of medicinal chemistry 159, 243-254, 2018 | 29 | 2018 |
| Alkoxide coordination of iron (III) protoporphyrin IX by antimalarial quinoline methanols: a key interaction observed in the solid-state and solution J Gildenhuys, CJ Sammy, R Müller, VA Streltsov, T le Roex, D Kuter, ... Dalton Transactions 44 (38), 16767-16777, 2015 | 24 | 2015 |
| The Effects of Quinoline and Non-quinoline Inhibitors on the Kinetics of Lipid-mediated β-Hematin Crystallization SM Fitzroy, J Gildenhuys, T Olivier, NO Tshililo, D Kuter, KA de Villiers Langmuir 33 (30), 7529-7537, 2017 | 19 | 2017 |
| Insights into the initial stages of lipid-mediated haemozoin nucleation D Kuter, R Mohunlal, SM Fitzroy, C Asher, PJ Smith, TJ Egan, ... CrystEngComm 18 (27), 5177-5187, 2016 | 19 | 2016 |
| Three 4-aminoquinolines of antimalarial interest SA Bourne, K De Villiers, TJ Egan Acta Crystallographica Section C: Crystal Structure Communications 62 (2 …, 2006 | 10 | 2006 |
| Design, Synthesis, and Evaluation of Novel Ferroquine and Phenylequine Analogues as Potential Antiplasmodial Agents L Jacobs, C de Kock, KA de Villiers, PJ Smith, VJ Smith, WAL van Otterlo, ... ChemMedChem 10 (12), 2099-2110, 2015 | 7 | 2015 |
| Iron (III) Protoporphyrin IX and Hemozoin: Key Targets in the Chemotherapy of Malaria KA de Villiers, TJ Egan Handbook of Porphyrin Science (Volume 27) With Applications to Chemistry …, 2014 | 6 | 2014 |
| Differential speciation of ferriprotoporphyrin IX in the presence of free base and diprotic 4-aminoquinoline antimalarial drugs J Gildenhuys, R Müller, T le Roex, KA de Villiers Solid State Sciences 65, 95-99, 2017 | 3 | 2017 |
